Comparison between Single and Double Cleavage-Stage Embryo Transfers, Single and Double Blastocyst Transfers in a South East Asian In Vitro Fertilisation Centre.
CONCLUSION: We found that single blastocysts stage embryo transfer is associated with similar LBR and CPR compared to double blastocysts stage embryo transfer and DET, with lower MPRs, and should be offered as standard practice, where possible. PMID: 30578424 [PubMed - in process] (Source: Annals of the Academy of Medicine, Singapore)
Source: Annals of the Academy of Medicine, Singapore - November 1, 2018 Category: General Medicine Authors: Kwek LK, Saffari SE, Tan HH, Chan JK, Nada S Tags: Ann Acad Med Singapore Source Type: research

Identification and Measurement of Frailty: A Scoping Review of Published Research from Singapore.
CONCLUSION: Our scoping review provided a broad evidence synthesis of the underpinnings of research on frailty identification and measurement in Singapore. Consistently applying standard methods and approaches in frailty identification and measurement can support evidence-based practice and policies in Singapore. PMID: 30578425 [PubMed - in process] (Source: Annals of the Academy of Medicine, Singapore)
Source: Annals of the Academy of Medicine, Singapore - November 1, 2018 Category: General Medicine Authors: Bautista MAC, Malhotra R Tags: Ann Acad Med Singapore Source Type: research

Relapsing Course of Sulfasalazine-Induced Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Complicated by Alopecia Universalis and Vitiligo.
Abstract PMID: 30578426 [PubMed - in process] (Source: Annals of the Academy of Medicine, Singapore)
Source: Annals of the Academy of Medicine, Singapore - November 1, 2018 Category: General Medicine Authors: Lian BS, Busmanis I, Lee HY Tags: Ann Acad Med Singapore Source Type: research

Percutaneous Radiologically-Guided Gastrostomy (PRG): Safety, Efficacy and Trends in a Single Institution.
Abstract PMID: 30578427 [PubMed - in process] (Source: Annals of the Academy of Medicine, Singapore)
Source: Annals of the Academy of Medicine, Singapore - November 1, 2018 Category: General Medicine Authors: Low GZ, Too CW, Poh YY, Lo RH, Tan BS, Gogna A, Irani FG, Tay KH Tags: Ann Acad Med Singapore Source Type: research

Climate Change and Infectious Diseases: The Next 50 Years.
Abstract PMID: 30460966 [PubMed - in process] (Source: Annals of the Academy of Medicine, Singapore)
Source: Annals of the Academy of Medicine, Singapore - October 1, 2018 Category: General Medicine Authors: Dennis S, Fisher D Tags: Ann Acad Med Singapore Source Type: research

Antenatal Anxiety: Prevalence and Patterns in a Routine Obstetric Population.
CONCLUSION: Antenatal anxiety symptoms are common even in normal pregnancies, especially among women with depression and lower education. Our study indicates value in exploring diagnostic criteria and quantitative measures for antenatal anxiety. PMID: 30460967 [PubMed - in process] (Source: Annals of the Academy of Medicine, Singapore)
Source: Annals of the Academy of Medicine, Singapore - October 1, 2018 Category: General Medicine Authors: Chua TE, Bautista DC, Tan KH, Yeo G, Chen H Tags: Ann Acad Med Singapore Source Type: research

Five-Year Review of Patients Presenting with Non-Accidental Injury to a Children's Emergency Unit in Singapore.
CONCLUSION: Analysing these factors provide a better understanding of  the presentation of  NAI cases, including 'red flags' and vulnerable groups who should have better protection. PMID: 30460968 [PubMed - in process] (Source: Annals of the Academy of Medicine, Singapore)
Source: Annals of the Academy of Medicine, Singapore - October 1, 2018 Category: General Medicine Authors: Chew YR, Cheng MH, Goh MC, Shen L, Wong PC, Ganapathy S Tags: Ann Acad Med Singapore Source Type: research

Periorbital Cellulitis in Paediatric Emergency Medicine Department Patients.
Abstract PMID: 30460969 [PubMed - in process] (Source: Annals of the Academy of Medicine, Singapore)
Source: Annals of the Academy of Medicine, Singapore - October 1, 2018 Category: General Medicine Authors: James V, Mohamad Ikbal MF, Min NC, Chan YH, Ganapathy S Tags: Ann Acad Med Singapore Source Type: research

Bicycle-Related Injuries in Paediatric Patients.
Abstract PMID: 30460970 [PubMed - in process] (Source: Annals of the Academy of Medicine, Singapore)
Source: Annals of the Academy of Medicine, Singapore - October 1, 2018 Category: General Medicine Authors: Peter L, Hong CC, Daniel P, Aoyama R, Murphy D, Kuan WS Tags: Ann Acad Med Singapore Source Type: research

Papular Purpuric Glove and Socks Syndrome with Evolution into Pemphigus Vulgaris.
Abstract PMID: 30460971 [PubMed - in process] (Source: Annals of the Academy of Medicine, Singapore)
Source: Annals of the Academy of Medicine, Singapore - October 1, 2018 Category: General Medicine Authors: Phuan CZ, Tan LS, Tey HL Tags: Ann Acad Med Singapore Source Type: research

Patient-Surrogate Agreement in Advance Care Planning: Who Are the Surrogates and Are They Making the Right Decisions?
Abstract PMID: 30460972 [PubMed - in process] (Source: Annals of the Academy of Medicine, Singapore)
Source: Annals of the Academy of Medicine, Singapore - October 1, 2018 Category: General Medicine Authors: Toh HJ, Tan L, Sim LK, Low JA Tags: Ann Acad Med Singapore Source Type: research

Predicting Suicide and its Prevention.
Abstract PMID: 30324963 [PubMed - in process] (Source: Annals of the Academy of Medicine, Singapore)
Source: Annals of the Academy of Medicine, Singapore - September 1, 2018 Category: General Medicine Authors: Wong JC Tags: Ann Acad Med Singapore Source Type: research

Deliberate Self-Harm in Psychiatric Outpatients Aged 14-35 Years in Singapore.
CONCLUSION: There was a high prevalence of DSH in the psychiatric outpatient population. The risk factors identified in this study are consistent with those of international studies which point to their stability across cultures. PMID: 30324964 [PubMed - in process] (Source: Annals of the Academy of Medicine, Singapore)
Source: Annals of the Academy of Medicine, Singapore - September 1, 2018 Category: General Medicine Authors: Shahwan S, Abdin E, Zhang Y, Sambasivam R, Fauziana R, Mahesh M, Ong SH, Chong SA, Subramaniam M Tags: Ann Acad Med Singapore Source Type: research

Does Low Birth Weight Vary Geospatially in Singapore?
CONCLUSION: There was no evidence of clustering of LBW rates among planning areas in Singapore that would indicate inequitable distribution of health resources among planning areas. The 2 areas showing the highest rates of LBW infants were Outram and Bukit Merah. We recommend targeted health interventions and outreach programmes to encourage antenatal visits in these areas. PMID: 30324965 [PubMed - in process] (Source: Annals of the Academy of Medicine, Singapore)
Source: Annals of the Academy of Medicine, Singapore - September 1, 2018 Category: General Medicine Authors: Sasha SR, Saffari SE, Allen JC, Yeo GS, Tan KH Tags: Ann Acad Med Singapore Source Type: research

Cancer Immunotherapy - The Target is Precisely on The Cancer and Also Not.
Abstract In recent years, the impressive number of cancer immunotherapy drugs approved has been unprecedented-building on over a century of understanding on how the immune system combats cancer, and how cancer evades it. Leading the charge are the immune checkpoint inhibitor monoclonal antibodies, and adoptive cell therapy with chimeric- antigen-receptor (CAR)-T cell therapy. These breakthrough therapies have led to improved survival in patients with many advanced cancers. Some of the clinical outcomes have been striking, and may even be potentially curative in some terminal cancer patients. While immune c...
Source: Annals of the Academy of Medicine, Singapore - September 1, 2018 Category: General Medicine Authors: Koo SL, Wang WW, Toh HC Tags: Ann Acad Med Singapore Source Type: research