Association between functional iron deficiency and reactive thrombocytosis in hospitalised patients: a case-control study
The association of deficiency in total body iron with an increased risk of reactive thrombocytosis is well known, but whether ‘functional iron deficiency’ is also associated with reactive thrombocytosis is unknown. This retrospective case-control study assessed the relationships between functional iron deficiency, reactive thrombocytosis and risk of thromboembolism. A total of 150 patients with reactive thrombocytosis (platelet count>400 x 109/l) and 343 controls (platelet count (Source: Anaesthesia and Intensive Care)
Source: Anaesthesia and Intensive Care - November 10, 2016 Category: Anesthesiology Source Type: research

Pharmacological agents for reducing the haemodynamic response to tracheal intubation in paediatric patients: a systematic review
The primary aim of this review was to assess the effect of pharmacological agents administered to attenuate the haemodynamic response to tracheal intubation in paediatric patients up to 16 years of age undergoing elective surgery. Secondary aims were to identify adverse effects related to these agents, and the agents ’ roles in decreasing arrhythmias. A systematic search was conducted for articles listed in PubMed, CINAHL or the Cochrane database between January 1980 and June 2014. We included randomised controlled trials where the stated aim of the study included observing the effects of pharmacological agent s on the h...
Source: Anaesthesia and Intensive Care - November 10, 2016 Category: Anesthesiology Source Type: research

Current limitations of the assessment of haemostasis in adult extracorporeal membrane oxygenation patients and the role of point-of-care testing
Haemostatic perturbations are commonly seen in extracorporeal membrane oxygenation (ECMO) patients and remain a clinical challenge, contributing significantly to morbidity and mortality. The approach to anticoagulation monitoring and the management of bleeding varies considerably across ECMO centres. Routine laboratory tests have their limitations in terms of turnaround time and specificity of information provided. Newer point-of-care testing (POCT) for coagulation may overcome these issues, as it provides information about the entire coagulation pathway from clot initiation to lysis. It is also possible to obtain qualitat...
Source: Anaesthesia and Intensive Care - November 10, 2016 Category: Anesthesiology Source Type: research

Anaesthetic implications of the changing management of patients with mucopolysaccharidosis
The mucopolysaccharidoses are a group of inherited metabolic disorders that are renowned for presenting clinical problems, particularly related to cardiac, airway, and skeletal abnormalities, in children during anaesthesia. The changing clinical management of the mucopolysaccharidoses can be described in three phases. An initial phase of accumulation and dissemination of knowledge about the management of this rare disease with a growing recognition that untreated Hurler syndrome and more severe forms of other phenotypes such as Hunter syndrome and Maroteaux –Lamy syndrome were associated with severe complications under a...
Source: Anaesthesia and Intensive Care - November 10, 2016 Category: Anesthesiology Source Type: research

Taken as read but not cited
(Source: Anaesthesia and Intensive Care)
Source: Anaesthesia and Intensive Care - November 10, 2016 Category: Anesthesiology Source Type: research