Evaluation of sensitivity and specificity of bone marrow trephine biopsy tests in an Indian teaching hospital
Conclusion BMB (aided with I.H.C) is a gold standard test for detecting different haematological and non hamatological disorders. In our study the sensitivity and specificity of BMB test was 84% and 90% respectively. When performed in association with BMA in the same sitting, significantly augments the chances of reaching a correct diagnosis. (Source: Alexandria Journal of Medicine)
Source: Alexandria Journal of Medicine - May 5, 2017 Category: Journals (General) Source Type: research
The effects of valproic acid on the mRNA expression of Natriuretic Peptide Receptor A and KQT-like subfamily Q-1 in human colon cancer cell lines
Conclusion The alteration of NPR-A and KCNQ1 genes were more ordered among SW-480 cancer cells. The expressional changes of KCNQ1 and NPR-A among VPA treated human colon cancer cells follow the same pattern in similar combinations. VPA could regulate the expression of KCNQ1 through altering the mRNA expression of NPR-A. (Source: Alexandria Journal of Medicine)
Source: Alexandria Journal of Medicine - April 28, 2017 Category: Journals (General) Source Type: research
Assessing prescriber ’s awareness of essential medicine list, hospital drug formulary and utilization of standard treatment guidelines in a tertiary healthcare facility in North-Central Nigeria
Publication date: Available online 26 April 2017 Source:Alexandria Journal of Medicine Author(s): Abdullahi Hassan, Gobir Abdulrazaq Abdullahi, Abubakar Aisha Ahmed, Adamu Sabiu, Uwaya John, Gwamna Ezekeil, Yahaya Aliyu Ibrahim (Source: Alexandria Journal of Medicine)
Source: Alexandria Journal of Medicine - April 26, 2017 Category: Journals (General) Source Type: research
Liver enzyme elevations in a cohort of HIV/AIDS patients on first-line antiretroviral therapy in Namibia: Findings and implications
Conclusions First line ART commonly induces mild self-limiting liver enzyme elevation in Namibian HIV patients especially in the first 3months. Consequently, there is a need to monitor ALT levels for at least 3months after initiation mainly in high risk patients to reduce side-effect concerns. This is already happening. (Source: Alexandria Journal of Medicine)
Source: Alexandria Journal of Medicine - April 13, 2017 Category: Journals (General) Source Type: research
Protective role of Spondias mombin leaf and Cola acuminata seed extracts against scopolamine-induced cognitive dysfunction
This study sought to investigate the protective effect of hydroethanolic leaf extract of Spondias mombin (SM) and Cola acuminata seed extract (CA) against scopolamine-induced cognitive dysfunction. SM or CA (50, 100 or 200mg/kg, p.o.) or SM+CA (50mg/kg, p.o.) was administered to rats for 3 consecutive days. One hour post-treatment on day 3, scopolamine (3mg/kg i.p) was administered and 5min later, the Y-maze test or Morris water maze test (MWM; days 3–7) was conducted. The rat’s brains were isolated for the estimation of oxidative-nitritive stress status following the MWM task. The antioxidant capacity of SM and CA was...
Source: Alexandria Journal of Medicine - April 10, 2017 Category: Journals (General) Source Type: research
