Plasma soluble CD 163 level as a marker of oesophageal varices in cirrhotic patients
Conclusion Serum soluble CD163 is a good noninvasive predictor for the presence of EVs and it may be used for grading of EVs. Its level does not change after esophageal varices eradication. Trial registration: IRB No: 00007589 FWA No: 00015712 The Ethics Committee of the faculty of medicine Alexandria University. (Source: Alexandria Journal of Medicine)
Source: Alexandria Journal of Medicine - April 14, 2018 Category: General Medicine Source Type: research

Neuronal and glial regeneration after focal cerebral ischemia in rat, an immunohistochemical and electron microscopical study
Conclusions We concluded that in spite of extensive proliferation; neuronal and glial regeneration occurs after MCAO only to a small extent. Revascularization seems to be an important initial step. The observed functional recovery of experimental animals may be due to neuronal plasticity in young rats rather than structural regeneration. (Source: Alexandria Journal of Medicine)
Source: Alexandria Journal of Medicine - April 14, 2018 Category: General Medicine Source Type: research

Impact of methylenetetrahydrofolate reductase (MTHFR) A1298C gene polymorphism on the outcome of methotrexate treatment in a sample of Egyptian rheumatoid arthritis patients
Conclusion: Our study proved that MTHFR A1298C SNP can predict clinical outcome of MTX treatment as regards treatment efficacy and toxicity in Egyptian rheumatoid arthritis patients. (Source: Alexandria Journal of Medicine)
Source: Alexandria Journal of Medicine - April 14, 2018 Category: General Medicine Source Type: research

Prevalence of pre-hypertension and hypertension and its related risk factors among undergraduate students in a Tertiary institution, Ghana
Conclusion The study revealed considerable prevalence rates of pre-hypertension and hypertension among undergraduate students, with significant risk factors such as obesity detected by BMI and WHtR. Gender as male was also significant for pre-hypertension and hypertension. Sound prevention and control programmes of hypertension should be devised among students, to improve their knowledge and lifestyle practices early in life. (Source: Alexandria Journal of Medicine)
Source: Alexandria Journal of Medicine - April 14, 2018 Category: General Medicine Source Type: research

Lateral ankle anatomical variants predisposing to peroneal tendon impingement
Conclusion The lateral ankle joint anatomical variants facilitate peroneal tendons injury, ending in chronic lateral joint instability. (Source: Alexandria Journal of Medicine)
Source: Alexandria Journal of Medicine - April 14, 2018 Category: General Medicine Source Type: research

The supracerebellar infratentorial approach in pineal region tumors: Technique and outcome in an underprivileged setting
Conclusion In Alexandria university, the supracerebellar infratentorial approach is considered a safe approach with minimal morbidity and no surgery related mortality. (Source: Alexandria Journal of Medicine)
Source: Alexandria Journal of Medicine - April 14, 2018 Category: General Medicine Source Type: research

Assessment of the onset of radiation-induced cardiac damage after radiotherapy of breast cancer patients
Conclusion the mean dose delivered to the heart is significantly higher in left-sided patients, and it was correlated to the total radiotherapy dose. One year after radiotherapy, ΔLVEF is possibly good marker of cardiotoxicity onset, however, the persistent elevation of both TnI and CK-MBRI could identify both patients with cardiotoxicity and patients that are thought to be in subclinical phase of cardiac damage. (Source: Alexandria Journal of Medicine)
Source: Alexandria Journal of Medicine - January 10, 2018 Category: General Medicine Source Type: research

Knowledge and practice of breast self-examination among sample of women in Shatra/Dhi-Qar/Iraq
Publication date: Available online 10 January 2018 Source:Alexandria Journal of Medicine Author(s): Salam Hussein Ewaid, Ali Muzahem Shanjar, Raghed Hadi Mahdi Objectives The knowledge and practice of breast self-examination (BSE) and breast cancer (BC) warning signs for the prevention purpose among females in Technical Institute of Shatra, Dhi-Qar Province, Iraq were investigated. Methods A cross-sectional survey by self-administered questionnaire prepared and 200 participants surveyed from January to March 2017 included 122 students, 45 teaching staff, and 33 employees. Results The results showed that 73% of stude...
Source: Alexandria Journal of Medicine - January 10, 2018 Category: General Medicine Source Type: research

Effect of metformin on Sirtuin-1 disorders associated with diabetes in male rats
Conclusion Lowered SIRT1 in diabetes was improved by the administration of Metformin. Consequently, the pathophysiological disorders associated with T2DM were improved. (Source: Alexandria Journal of Medicine)
Source: Alexandria Journal of Medicine - January 4, 2018 Category: General Medicine Source Type: research

Candidemia after cardiac surgery in Tehran, Iran: A retrospective analysis of 424 cases at two medical centers
Conclusions This study expands the knowledge of the epidemiology and trend of incidence of candidemia in cardiosurgical cases. The survey provides preliminary baseline data for the future monitoring of candidemia, and effective programs for controlling and preventive strategies against the disease in hospitals. (Source: Alexandria Journal of Medicine)
Source: Alexandria Journal of Medicine - December 7, 2017 Category: General Medicine Source Type: research

Zoonotic fungal diseases and animal ownership in Nigeria
Conclusion There is a need to raise awareness of the extent of health problems caused by zoonotic fungal diseases in Nigeria in order to better appreciate their burden and public health consequences, and also provide an integrated platform for development of effective prevention and control strategies. (Source: Alexandria Journal of Medicine)
Source: Alexandria Journal of Medicine - December 6, 2017 Category: General Medicine Source Type: research

Early prediction of iron deficiency in females in child bearing age in central Saudi Arabia
Publication date: Available online 6 December 2017 Source:Alexandria Journal of Medicine Author(s): Mysara M. Mogahed, Shereen Mohamed Abdelwahab (Source: Alexandria Journal of Medicine)
Source: Alexandria Journal of Medicine - December 6, 2017 Category: General Medicine Source Type: research

Comparing the efficiency of four diagnostic concentration techniques performed on the same group of intestinal parasites
Conclusion Tween, acetone and gasoline reagents are more stable, safer, less flammable and of lower cost than that of ether; and promise to be a useful alternative to ether- concentration. Our results demonstrated that the combined use of parasitological techniques is important for the diagnosis of all intestinal parasites. FTC and FGC techniques are superior for the diagnosis of helminth ova and protozoan cysts in stool, respectively. Additional studies are suggested, using a larger sample size and different parasites in the field. (Source: Alexandria Journal of Medicine)
Source: Alexandria Journal of Medicine - November 25, 2017 Category: General Medicine Source Type: research

Low cost detection of hepatitis C virus RNA in HCV infected patients by SYBR Green I real-time PCR
Conclusion This method is useful for rapid qualitative detection of HCV infection and particularly suitable for routine diagnostic applications. (Source: Alexandria Journal of Medicine)
Source: Alexandria Journal of Medicine - November 25, 2017 Category: General Medicine Source Type: research

Carpal tunnel syndrome in patients with and without diabetes mellitus in Upper Egypt: The impact of electrophysiological and ultrasonographical studies
Conclusion The CSA of median nerve is larger in CTS hands in both DM and non-DM patients. Mean electro-diagnostic parameters were not significant predictors of CTS in patients with diabetes. The combination of electrophysiological and ultrasonography provides diagnostic effective tools across the entire spectrum of CTS in diabetic and non-diabetic patients. Nevertheless, screening for DM in patients with CTS is not recommended. (Source: Alexandria Journal of Medicine)
Source: Alexandria Journal of Medicine - November 25, 2017 Category: General Medicine Source Type: research