Female scientist who turns down offer to work for free = whore... you can't make this $hit up
Mind officially blown.h/t IsisFor some reason (likely pertaining to my incompetence) Blogger isn't picking up the Yout00b clip for DNLees's response, but it's here so go watch.Oh, and this is one of the best responses to the emerging trend of expecting people to work for free (it's only writing, y'know...).UPDATE: The plot thickens... DNLee blogs for Scientific American, who appear to have removed her response from her blog feed. A look at Sci Am's list of partners reveals a mention for Biology Online, on whose behalf DNLee was being solicited by this Ofek fella. That's a bit dodgy, isn't it? (Source: Across the Bilayer)
Source: Across the Bilayer - October 12, 2013 Category: Medical Scientists Source Type: blogs
Understanding ion channels: The Cysteine Scanning Accessibility Method for eejits - Part The Third (whereupon I finally arrive at my point)
The Cysteine Scanning Accessibility Method involves the use of site-directed mutagenesis to substitute individual amino acids within a protein for Cys and then probing whether or not the introduced Cys side chain is subsequently accessible to water-soluble thiol-reactive agents. Conventionally, this involves generating a series of mutant ion channel subunits bearing single Cys point mutations at different amino acid positions along a stretch of the polypeptide. Each of these mutant subunits is then individually expressed into a model cell line (e.g. HEK293, or CHO) to form the functional mutant ion channels,...
Source: Across the Bilayer - October 8, 2013 Category: Medical Scientists Source Type: blogs
Linkage: "Don’t be that dude: Handy tips for the male academic" - by Tenure She Wrote
If people are looking at you like this, you may have said something insensitiveWorth a read. Although the title could just as easily have been left as, "Don’t be that dude: Handy tips for the male."Highlights:11. Learn about benevolent sexism 12. Learn what mansplaining is13. Learn what the tone argument is 14. Learn how to apologize when someone has called you out for inappropriate behavior. In re #14, I think social etiquette of the Old Skool variety actually pays off here. If a person registers offence at a remark one has made, it's just plain respectful and ...
Source: Across the Bilayer - October 2, 2013 Category: Medical Scientists Source Type: blogs
The Running Man
I'm often mistaken for Daniel Craig when I'm about town. True story.So... I went out for my usual run last night... 6 miles or so... Probably averaging 5 min/mile give-or-take... not my best, but not too shabby, all said and done...Okay, alright... it didn't go down quite like that. What I mean is that it wasn't really my "usual" run according to the conventional definition of the term "usual"; i.e. something that happens on a fairly regular temporal basis as opposed to just once in the last ten years.And, if we're going to be honest, it probably wasn't a full 6 miles. A little under 2 miles would be a more accurate e...
Source: Across the Bilayer - October 1, 2013 Category: Medical Scientists Tags: Irreducible absurdity Source Type: blogs
The Win Is Strong With This One, Padawans...
The Grauniad reports... Click pic for original articleBTW, Trekkies, how's that Transporter coming along? Bwa ha ha! Consider your tech Phot-owned*!* yeah, I kinda went there. Sorry :\ (Source: Across the Bilayer)
Source: Across the Bilayer - September 30, 2013 Category: Medical Scientists Tags: Science Source Type: blogs
Understanding ion channels: The Cysteine Scanning Accessibility Method for eejits - Part The Second (in which I ruggedly persevere in my efforts to avoid actually talking about the Cysteine Scanning Accessibility Method)
Figure 1. Thiol group of cysteine side chain can be covalently modified. Top shows the formation of a disulfide bond between two Cys side chains. Bottom shows covalent modification of a Cys side chain by MTSET+, a water-soluble thiol-reactive chemical.What's so hot about Cysteine?Short story: we can stick things to it.Long story: The amino acid Cysteine (Cys, or "C") contains a thiol group within its side chain, which can form covalent bonds with thiol-reactive and thiol group-containing molecules. In proteins, cysteine side chains that come into close proximity to on...
Source: Across the Bilayer - September 28, 2013 Category: Medical Scientists Tags: Science IonChannels Source Type: blogs
Scientific Setback #4256544338295531099994
When I sneeze, I always sneeze in pairs. It's a thing. A thing I had hitherto dismissed as an unserious, quirky, no-big-deal thing until just this last night when l sneezed with a mouthful of Listerine and disinfected my sinuses. "And it burns, burns, burns..." (Source: Across the Bilayer)
Source: Across the Bilayer - September 28, 2013 Category: Medical Scientists Source Type: blogs
Scienitific Setback #4256544338295531099994
When I sneeze, I always sneeze in pairs. It's a thing. A thing I had hitherto dismissed as an unserious, quirky, no-big-deal thing until just this last night when l sneezed with a mouthful of Listerine and disinfected my sinuses. "And it burns, burns, burns..." (Source: Across the Bilayer)
Source: Across the Bilayer - September 28, 2013 Category: Medical Scientists Source Type: blogs
Public Access Factor 9, Mr. Sulu
Michael Eisen is taking the colors and going over the top:"So what does NASA do to reward this outpouring of public interest (not to mention to $2.5 billion taxpayer dollars that made it possible)? They publish the first papers to arise from the project behind a Science magazine’s paywall...... in the interests of helping NASA and Science Magazine comply with US law, I am making copies of these papers freely available here"Take it to 'em, brother![h/t Drugmonkey] (Source: Across the Bilayer)
Source: Across the Bilayer - September 27, 2013 Category: Medical Scientists Source Type: blogs
Dulbecco's Modified Acoustic Medium
The other 50% of the blogosphere known to routinely wax lyrical on The Craft recently posted their current tune preferences for creating the optimum patch clamp environment.Here's what my transfected HEK293 cells are vibing to... Electronica for your bioelectronic explorations, yo:1 - In the Waiting Line - Zero 72 - Titanium - David Ghetta3 - Blue Jeans - Lana Del Rey (Kris Menace remix)4 - No light, no light - Florence + the Machine5 - Lights - Ellie Goulding (Bassnectar remix)6 - 3 Kilos - The Prodigy7 - Ecstasy - atb8 - Fire in Your New Shoes - Kaskade (feat. Martina of Dragonette)9 - Eye for an Eye - UNKLE10 ...
Source: Across the Bilayer - September 25, 2013 Category: Medical Scientists Source Type: blogs
Replicates and Repeats - what is the difference and is it significant
I recently excavated this nugget frommy ReadCube for reference purposes, and thought I'd post a link because it is a worthy read.The thing with Teh Scienze is that there is a not inconsiderable gap between the Popperian sphere of how it probably should be done, and the Kuhnian sphere of how it actually ends up being done. Scientists, particularly life scientists, regularly and quite violently abuse statistics. 'Tis true. Indeed, if statistics were living things, not a single one of us would get IRB approval to do the sorts of things we do to statistics on a regular basis. Madam, at best we're talking forcef...
Source: Across the Bilayer - September 24, 2013 Category: Medical Scientists Source Type: blogs
Humor doesn't get much darker than this...
(Source: Across the Bilayer)
Source: Across the Bilayer - September 24, 2013 Category: Medical Scientists Source Type: blogs
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(Source: Across the Bilayer)
Source: Across the Bilayer - September 24, 2013 Category: Medical Scientists Source Type: blogs
Coco reviewing video games... genius
(Source: Across the Bilayer)
Source: Across the Bilayer - September 20, 2013 Category: Medical Scientists Source Type: blogs
Grant writing/ghost writing... a new trend?
Fascinating discussion going on over at Drugmonkey's blog in re the use of professional grant writers at academic institutions. These folk are not uncommon in industry and at philanthropy-based non-profits from what I know, and are sometimes employed on an advisory basis within academic departments. However, one commenter employed as a grant writer at an academic institution appears to have more than a mere editing/advisory role, generating most of the proposal, and goings as far as to assist in troubleshoot experimental design: "I had a grant earlier this year with an Aim 3 done in a model that did not express the en...
Source: Across the Bilayer - September 19, 2013 Category: Medical Scientists Source Type: blogs
