In Search of Better Prognostic Tools in CRC
David Kerr reports on a study of the prognostic value of four gene signatures in CRC. The results underscore the need to more effectively capture tumor heterogeneity to better individualize therapy. (Source: Medscape Oncology)
Source: Medscape Oncology - November 11, 2014 Category: Cancer & Oncology Authors: Medscape Source Type: podcasts

Confirmed: Abiraterone Ups Overall Survival in mCRPC
Drs Cora Sternberg and Stéphane Oudard highlight practice-changing data in prostate cancer, presented at ESMO 2014, including the long-awaited survival results of the COU-AA-302 study. (Source: Medscape Oncology)
Source: Medscape Oncology - October 13, 2014 Category: Cancer & Oncology Authors: Medscape Source Type: podcasts

Refining Sunitinib Use Extends Survival in RCC
Dr Bernard Escudier highlights the renal cancer presentations from ESMO 2014, focusing on data on gene signatures, new uses of old drugs, and promising combinations to improve survival. (Source: Medscape Oncology)
Source: Medscape Oncology - October 10, 2014 Category: Cancer & Oncology Authors: Medscape Source Type: podcasts

BRAF/MEK Increases Overall Survival in Melanoma
A tripling of response with nivolumab and the first study in which a BRAF/MEK combo increases overall survival are among the melanoma highlights at ESMO 2014, reported by Dr Antoni Ribas. (Source: Medscape Oncology)
Source: Medscape Oncology - October 9, 2014 Category: Cancer & Oncology Authors: Medscape Source Type: podcasts

The 'Fab Five' Rock Lymphoma
Dr Martin Dreyling reviews recent data in lymphoma indicating that the command performance of five biologic agents do all but lock the door on chemotherapy and throw away the key. (Source: Medscape Oncology)
Source: Medscape Oncology - October 9, 2014 Category: Cancer & Oncology Authors: Medscape Source Type: podcasts

Too Soon for Broad BRCA Screening
Dr Maurie Markman discusses the controversy surrounding routine BRCA screening for breast and ovarian cancer and suggests that it is too soon for widespread genetic screening. (Source: Medscape Oncology)
Source: Medscape Oncology - October 7, 2014 Category: Cancer & Oncology Authors: Medscape Source Type: podcasts

Positive Findings for HER2-Negative Breast Cancer
Drs Fabrice André and Gunter von Minckwitz review potentially practice-changing and practice-confirming studies in HER2+ and HER2- breast cancer, presented at ESMO 2014. (Source: Medscape Oncology)
Source: Medscape Oncology - October 6, 2014 Category: Cancer & Oncology Authors: Medscape Source Type: podcasts

Use 'TKI as Long as You Can' in NSCLC
Two studies presented at ESMO 2014 clarify the sequence of therapies after disease progression in EGFR-mutated non-small cell lung cancer. (Source: Medscape Oncology)
Source: Medscape Oncology - October 6, 2014 Category: Cancer & Oncology Authors: Medscape Source Type: podcasts

The Value of Multiplex Genotyping for Lung Cancer
Dr Mark Kris discusses the development of the Lung Cancer Mutation Consortium, a group of lung cancer specialists who sought to prove the value of multiplex genotyping. (Source: Medscape Oncology)
Source: Medscape Oncology - September 29, 2014 Category: Cancer & Oncology Authors: Medscape Source Type: podcasts

BRCA Screening: Good Sense or Gattaca Rising?
Does population screening for BRCA mutations portend a eugenics future, as in 'Gattaca,' or a practical means to reduce the risk for breast and ovarian cancer? Dr. Kathy Miller weighs the issues. (Source: Medscape Oncology)
Source: Medscape Oncology - September 24, 2014 Category: Cancer & Oncology Authors: Medscape Source Type: podcasts

Bevacizumab's Role in Late-Stage Cervical Cancer
Dr. Maurie Markman discusses the recent FDA approval of bevacizumab for recurrent or late-stage cervical cancer and weighs the benefits of the drug in this setting against its toxicity profile. (Source: Medscape Oncology)
Source: Medscape Oncology - September 24, 2014 Category: Cancer & Oncology Authors: Medscape Source Type: podcasts

ESMO Preview: Precision Medicine and Picasso
Dr. David Kerr previews the scientific program of ESMO 2014 and offers his top picks for key colorectal studies plus a few not-to-be-missed masterworks from Madrid's museums. (Source: Medscape Oncology)
Source: Medscape Oncology - September 22, 2014 Category: Cancer & Oncology Authors: Medscape Source Type: podcasts

Genotyping in Lung Cancer: New Opportunities, New Challenges
Dr Ronald Wharton reviews images from a patient with a bioprosthetic aortic valve and a mitral-valve ring annuloplasty. (Source: Medscape Oncology)
Source: Medscape Oncology - September 18, 2014 Category: Cancer & Oncology Authors: Medscape Source Type: podcasts

'Got It Right': Guidelines for HER2-Negative Breast Cancer
Dr. Kathy Miller says the ASCO guidelines for advanced HER2-negative breast cancer 'got it right,' focusing on HT, sequential chemo agents, and decisions made jointly by doctors and patients. (Source: Medscape Oncology)
Source: Medscape Oncology - September 10, 2014 Category: Cancer & Oncology Authors: Medscape Source Type: podcasts

'Fiasco' Over PSA Test Should Never Happen Again
It's all about the cost/benefit ratio in screening for prostate cancer, says Dr. Gerald Chodak, although many people continue to misunderstand the real numbers. (Source: Medscape Oncology)
Source: Medscape Oncology - August 29, 2014 Category: Cancer & Oncology Authors: Medscape Source Type: podcasts