Thermophilic Microbes in Environmental and Industrial Biotechnology
Biotechnology of ThermophilesThe existence of life at high temperatures is quiet fascinating. At elevated temperatures, only microorganisms are capable of growth and survival. Many thermophilic microbial genera have been isolated from man-made (washing machines, factory effluents, waste streams and acid mine effluents) and natural (volcanic areas, geothermal areas, terrestrial hot springs, submarine hydrothermal vents, ... (Source: Springer Biomedical Sciences titles)
Source: Springer Biomedical Sciences titles - March 30, 2013 Category: Biomedical Science Tags: Biomedicine (general) Source Type: news

The Principles of Clinical Cytogenetics
(Source: Springer Biomedical Sciences titles)
Source: Springer Biomedical Sciences titles - March 28, 2013 Category: Biomedical Science Tags: Cytogenetics Source Type: news

Application of Near Infrared Spectroscopy in Biomedicine
series:Handbook of Modern BiophysicsIn keeping with the style of the Handbook of Modern Biophysics, this fourth volume, Application of Near-Infrared Spectroscopy in Biomedicine, balances the need for physical science/mathematics formalism with a demand for biomedical perspectives. Each chapter divides the presentation into two major parts: the first establishes the conceptual framework and describes the instrumentation or ... (Source: Springer Biomedical Sciences titles)
Source: Springer Biomedical Sciences titles - March 27, 2013 Category: Biomedical Science Tags: Biomedicine (general) Source Type: news

Multiple Origins of Sex Differences in Brain
Neuroendocrine Functions and their Pathologiesseries:Research and Perspectives in Endocrine InteractionsIn theoretical terms, sex differences in brain and behavior offer the possibility of fascinating scientific studies on a range of molecular phenomena such as DNA methylation, chromatin protein modification, non-coding DNA, resulting in important neuroanatomical and neurochemical effects. However, this general subject has been treated with much hyperbole. Historically, sex differences were ... (Source: Springer Biomedical Sciences titles)
Source: Springer Biomedical Sciences titles - March 3, 2013 Category: Biomedical Science Tags: Neurosciences Source Type: news

Tight Junctions in Cancer Metastasis
series:Cancer Metastasis - Biology and TreatmentThere has been a dramatic increase in knowledge of tight junctions in the past decade. The molecular structure of tight junctions, cellular functions and the pathophysiological roles of tight junctions are becoming clear. Of the most important functions, the role of the cellular structure in cancer spread and drug delivery are increasingly realised. It is now clear that there are fundamental ... (Source: Springer Biomedical Sciences titles)
Source: Springer Biomedical Sciences titles - March 3, 2013 Category: Biomedical Science Tags: Biomedicine (general) Source Type: news

Biophysics for Therapeutic Protein Development
series:Biophysics for the Life SciencesThe last few decades have seen the genesis of protein therapeutics, such that these large molecule based drugs comprise an increasingly larger part of the commercial market. The conformation (overall global fold or three-dimensional structure) of these molecules is important for maintaining biological activity, stability during long term storage, and can impact the safety profile and ... (Source: Springer Biomedical Sciences titles)
Source: Springer Biomedical Sciences titles - March 2, 2013 Category: Biomedical Science Tags: Pharmacology / Toxicology Source Type: news

Gene Regulation
Methods and Protocolsseries:Methods in Molecular BiologyIn this volume of Methods in Molecular Biology™, expert investigators offer comprehensive, complementary, and cutting-edge technologies for studies of gene regulation.  The chapters of Gene Regulation: Methods and Protocols are organized to provide an integrated and a coherent view of control systems and their associated components.  The protocols are broad in their scope.  They include ... (Source: Springer Biomedical Sciences titles)
Source: Springer Biomedical Sciences titles - March 1, 2013 Category: Biomedical Science Tags: Human Genetics Source Type: news

Target Identification and Validation in Drug Discovery
Methods and Protocolsseries:Methods in Molecular BiologyThe major reason for the elevated costs of drug development in the pharmaceutical industry is the high attrition rate. In Target Identification and Validation in Drug Discovery: Methods and Protocols, expert researchers in the field detail many of the methods which are now commonly used to identify and validate new target. These include methods and approaches covering biochemical, cell based, ... (Source: Springer Biomedical Sciences titles)
Source: Springer Biomedical Sciences titles - March 1, 2013 Category: Biomedical Science Tags: Pharmacology / Toxicology Source Type: news

Neuroscience in the 21st Century
From Basic to ClinicalEdited and authored by a wealth of international experts in neuroscience and related disciplines, the aim behind this key new resource is to offer medical students and graduate researchers around the world a comprehensive introduction and overview of modern neuroscience. Neuroscience research is certain to prove a vital element in combating mental illness in its various incarnations, a ... (Source: Springer Biomedical Sciences titles)
Source: Springer Biomedical Sciences titles - March 1, 2013 Category: Biomedical Science Tags: Neurosciences Source Type: news

Heart Valves
From Design to Clinical ImplantationCardiovascular disease is the major cause of morbidity and mortality worldwide. While the past 40 years have brought major progress in cardiac valve repair and replacement, there remain large patient populations that do not receive such therapies. This, in turn, implies a great need for future basic, applied, and clinical research and, ultimately, therapeutic developments. Heart Valves is a ... (Source: Springer Biomedical Sciences titles)
Source: Springer Biomedical Sciences titles - February 20, 2013 Category: Biomedical Science Tags: Biomedicine (general) Source Type: news

Polypharmacy in Psychiatry Practice, Volume I
Multiple Medication Use StrategiesDespite the large number of psychotropic medications currently available, effective management of mental disorders continues to be a challenging task. Although monotherapy may be desirable, most patients require combinations of two or more psychotropic drugs. Polypharmacy aims to address different aspects of treatment resistance, especially insufficient response of positive and negative ... (Source: Springer Biomedical Sciences titles)
Source: Springer Biomedical Sciences titles - February 20, 2013 Category: Biomedical Science Tags: Biomedicine (general) Source Type: news

Polypharmacy in Psychiatry Practice, Volume II
Use of Polypharmacy in the "Real World"Despite the large number of psychotropic medications currently available, effective management of mental disorders continues to be a challenging task. Although monotherapy may be desirable, most patients require combinations of two or more psychotropic drugs. Polypharmacy aims to address different aspects of treatment resistance, especially insufficient response of positive and negative ... (Source: Springer Biomedical Sciences titles)
Source: Springer Biomedical Sciences titles - February 20, 2013 Category: Biomedical Science Tags: Biomedicine (general) Source Type: news

Androgen-Responsive Genes in Prostate Cancer
Regulation, Function and Clinical ApplicationsRecent studies demonstrated a key role of the androgen receptor in the development of castration-recurrent or -resistant prostate cancer (CRPC), which is deadly and in urgent need of more effective therapies.  Understanding the functions of androgen-responsive genes and their regulation and deregulation in prostate cancer progression may lead to new approaches to prevent and treat prostate ... (Source: Springer Biomedical Sciences titles)
Source: Springer Biomedical Sciences titles - February 20, 2013 Category: Biomedical Science Tags: Cancer Research Source Type: news

Array Comparative Genomic Hybridization
Protocols and Applicationsseries:Methods in Molecular BiologyThe earliest descriptions of human chromosomes initiated the genomics revolution that is now upon us. Array Comparative Genomic Hybridization: Protocols and Applications explores the scope of what is now possible as far as documenting abnormalities associated with several human cancers. While the technology for interrogating the human genome continues to evolve, refinement of comparative ... (Source: Springer Biomedical Sciences titles)
Source: Springer Biomedical Sciences titles - February 20, 2013 Category: Biomedical Science Tags: Human Genetics Source Type: news

Cancer Genomics
Molecular Classification, Prognosis and Response PredictionThe combination of molecular biology, engineering and bioinformatics has revolutionized our understanding of cancer revealing a tight correlation of the molecular characteristics of the primary tumor in terms of gene expression, structural alterations of the genome, epigenetics and mutations with  its propensity to metastasize and to respond to therapy. It is not just one or a few genes, it is ... (Source: Springer Biomedical Sciences titles)
Source: Springer Biomedical Sciences titles - February 19, 2013 Category: Biomedical Science Tags: Cancer Research Source Type: news