Mouse and zebrafish genome annotations updated
The mouse (GRCm38.p4) and zebrafish (GRCz10) genomes were recently re-annotated by the Eukaryotic Genome Annotation Pipeline. For both, the annotation was performed on the RefSeq assemblies' top-level sequences (chromosomes and unlocalized and unplaced scaffolds). See our previous announcement for details about this change. (Source: NCBI Announcements)
Source: NCBI Announcements - July 6, 2016 Category: Databases & Libraries Source Type: news
Genome Workbench 2.10.7 now available
Genome Workbench 2.10.7 brings a number of new features and fixes like added support for local custom BLAST databases and improvements to Tree View. (Source: NCBI Announcements)
Source: NCBI Announcements - June 30, 2016 Category: Databases & Libraries Source Type: news
July 6th NCBI Minute: Quickly Find Coding Sequences Using ORFfinder
In one week, we’ll show you how to use the redesigned Open Reading Frame Finder (ORFfinder) to quickly identify and analyze complete coding regions on prokaryotic genomic and eukaryotic mRNA sequences. (Source: NCBI Announcements)
Source: NCBI Announcements - June 27, 2016 Category: Databases & Libraries Source Type: news
Human genome Annotation Release 108 incorporates new RefSeq sequences, predicts new variants
The Eukaryotic Genome Annotation Pipeline recently produced an updated annotation of the human genome. This new annotation, available in RefSeq, incorporates new "known" RefSeq sequences and predicts new alternative variants. For the first time, this annotation was performed on the assemblies' top-level sequences (chromosomes and unlocalized and unplaced scaffolds). See our previous announcement for details about this change. (Source: NCBI Announcements)
Source: NCBI Announcements - June 24, 2016 Category: Databases & Libraries Source Type: news
GenBank release 214.0 is now available via FTP
GenBank release 214.0 (06/14/2016) has 194,463,572 traditional records containing 213,200,907,819 base pairs of sequence data. In addition, there are 350,278,081 WGS records containing 1,556,175,944,648 base pairs of sequence data, as well as 104,677,061 TSA records containing 94,413,958,919 base pairs of sequence data. (Source: NCBI Announcements)
Source: NCBI Announcements - June 23, 2016 Category: Databases & Libraries Source Type: news
June 29th webinar: Downloading Exon and Coding Region Sequences for Genes
Next Wednesday, June 29th, NCBI staff will show you how to use the Gene Table report and Graphical Viewer to retrieve exon sequences for genes. (Source: NCBI Announcements)
Source: NCBI Announcements - June 20, 2016 Category: Databases & Libraries Source Type: news
International HapMap Browser to go offline June 16, 2016
Due to computer security flaws within the HapMap site, it has been decommissioned as of today, June 16, 2016. We regret any inconvenience this sudden removal may cause, but we are acting quickly to ensure security. (Source: NCBI Announcements)
Source: NCBI Announcements - June 16, 2016 Category: Databases & Libraries Source Type: news
NCBI to hold hackathon on NIH campus in August
The NCBI and several NIH institutes will host a biomedical data science hackathon at the National Library of Medicine from August 15th to 17th. To apply for this hackathon, complete this form (approximately 10 minutes to complete). Applications are due July 11th, by 4PM ET. (Source: NCBI Announcements)
Source: NCBI Announcements - June 14, 2016 Category: Databases & Libraries Source Type: news
BLAST+ 2.4.0 now available
Version 2.4.0 of the BLAST+ executables offers improved scoring for selenocysteine residues in the query and database sequences, as well as improved performance for the BLASTP/BLASTX/BLASTN programs. (Source: NCBI Announcements)
Source: NCBI Announcements - June 13, 2016 Category: Databases & Libraries Source Type: news
NCBI will transition to HTTPS on September 1, 2016
Starting on September 1st, when you visit NCBI pages, you’ll see a green lock and https:// in the address bar instead of http://. This lets you know that you are really on an NCBI page – that our server identity is confirmed – and that your communication with our server is encrypted and private. (Source: NCBI Announcements)
Source: NCBI Announcements - June 10, 2016 Category: Databases & Libraries Source Type: news
Tree Viewer 1.9 visualizes medium-large phylogenetic trees
The latest version of Tree Viewer can now visualize medium-large phylogenetic trees up to 15,000 nodes. Tree Viewer 1.9 also includes mini URLs in Link to View, and several other improvements and bug fixes. The Tree Viewer release notes list all updates. (Source: NCBI Announcements)
Source: NCBI Announcements - June 10, 2016 Category: Databases & Libraries Source Type: news
June 10th webinar: Finding Systematic Reviews at PubMed Health and PubMed
This Friday, NCBI will present a brief instructional webinar that will show you how to find systematic reviews using PubMed and PubMed Health. (Source: NCBI Announcements)
Source: NCBI Announcements - June 7, 2016 Category: Databases & Libraries Source Type: news
MutaBind: Evaluating the effects of sequence variants and disease mutations on protein-protein interactions
MutaBind is a new computational method and server created through NCBI research efforts that maps mutations on a protein structural complex, calculates changes in binding affinity, identifies deleterious mutations and produces a downloadable mutant structural model. (Source: NCBI Announcements)
Source: NCBI Announcements - June 3, 2016 Category: Databases & Libraries Source Type: news
Browse histones, analyze sequences with revamped HistoneDB 2.0
Created through research efforts at NCBI, HistoneDB 2.0 is a totally overhauled histone database that can be used to explore the diversity of histone proteins and their sequence variants in many organisms. (Source: NCBI Announcements)
Source: NCBI Announcements - June 1, 2016 Category: Databases & Libraries Source Type: news
June 15th webinar: Using NCBI Resources and Variant Interpretation Tools for the Clinical Community
In two weeks, NCBI will present a webinar that will show you how to use three clinical variant interpretation tools geared to clinicians through an overview of NCBI variation and medical genetics databases. A demonstration using a clinical case to demonstrate a phenotype-driven whole-genome sequence analysis using tools from Golden Helix, Omicia and SimulConsult will follow the overview. (Source: NCBI Announcements)
Source: NCBI Announcements - June 1, 2016 Category: Databases & Libraries Source Type: news
