FDG-PET parameter predicts locally advanced lung cancer survival
High post-treatment concentrations of a radioactive imaging marker are predictive of worse overall survival from inoperable, locally advanced non-small-cell lung cancer, prospective study findings suggest. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - October 31, 2013 Category: Cancer & Oncology Source Type: news

DNA methylation signature marks recurrence in early stage lung cancer
An international research team has identified a DNA methylation signature that identifies patients with stage I non-small-cell lung cancer who are at high risk for relapse. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - October 31, 2013 Category: Cancer & Oncology Source Type: news

Complement protein holds diagnostic, prognostic promise in lung cancer
A complement activation product known as “C4d” may have value as a diagnostic and prognostic biomarker for lung cancer, research suggests. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - October 28, 2013 Category: Cancer & Oncology Source Type: news

REGARD VEGF receptor-2 as gastric cancer target
Targeting vascular endothelial growth factor receptor-2 mediated signaling is an effective strategy against advanced gastric cancer, results from the REGARD trial demonstrate. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - October 22, 2013 Category: Cancer & Oncology Source Type: news

P400 predicts RCC outcome
Reduced expression of a senescence-associated protein is associated with worse outcome in patients with renal cell carcinoma, study findings show. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - October 22, 2013 Category: Cancer & Oncology Source Type: news

Prognostic factors could aid RCC metastasectomy decisions
Researchers have identified four factors that are associated with survival time in patients who undergo metastasectomy for metastatic renal cell carcinoma. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - October 22, 2013 Category: Cancer & Oncology Source Type: news

Stage and grade dominate RCC outcomes
Tumor grade and American Joint Committee on Cancer stage have emerged as the most important predictors of mortality in a competing risks analysis of patients undergoing nephrectomy for renal cell carcinoma. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - October 22, 2013 Category: Cancer & Oncology Source Type: news

BRCA1/2 mutations may alter endometrial, ovarian function
Scientists have detected significant differences in endometrial thickness and hormone levels in women with and without BRCA1/2 mutations that may play a role in cancer susceptibility or development. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - October 22, 2013 Category: Cancer & Oncology Source Type: news

Skin cancer drug shows periocular promise
Early research suggests that patients with periocular basal cell carcinoma may benefit from treatment with a drug targeting the Hedgehog signaling pathway. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - October 21, 2013 Category: Cancer & Oncology Source Type: news

Palliative chemoradiation boosts survival, QoL in poor-prognosis NSCLC
C hemoradiation is superior to chemotherapy alone with respect to both survival and quality of life in patients with inoperable non-small-cell lung cancer, a phase III trial has found. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - October 13, 2013 Category: Cancer & Oncology Source Type: news

HIV infection heralds worse outcomes in NSCLC
Infection with HIV is an indicator of poor prognosis in patients with non-small-cell lung cancer, analysis of epidemiologic data indicates. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - October 9, 2013 Category: Cancer & Oncology Source Type: news

Use of SHOX2 DNA measurement improves cancer staging tools
Findings indicate that assessment of SHOX2 DNA methylation level in lymph node tissue improves the negative predictive value of endobronchial ultrasound with transbronchial needle aspiration, as well as endoscopic lung cancer staging in general. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - October 4, 2013 Category: Cancer & Oncology Source Type: news

Intercalated erlotinib/chemotherapy shows mixed results in NSCLC
A study comparing erlotinib alone with erlotinib intercalated with chemotherapy has failed to demonstrate a clear advantage of the combination strategy when used to treat relapsed patients with non-small-cell lung cancer, Dutch researchers report. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - September 30, 2013 Category: Cancer & Oncology Source Type: news

Time to first cigarette independently predicts lung cancer
The time to first cigarette after waking is an independent risk factor for lung cancer, a Japanese case-control study has found. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - September 29, 2013 Category: Cancer & Oncology Source Type: news

Immunologic checkpoint inhibitor shows promise in malignant mesothelioma
Tremelimumab, one of a new class of immunomodulatory monoclonal antibodies, has shown encouraging clinical activity and acceptable tolerability in patients with chemotherapy-resistant malignant mesothelioma, results of a single-arm phase II study show. (Source: MedWire News - Oncology)
Source: MedWire News - Oncology - September 27, 2013 Category: Cancer & Oncology Source Type: news