Immunocytochemistry ‘highly accurate’ for ALK detection
Immunocytochemistry is highly accurate for detecting anaplastic lymphoma kinase rearrangements in non-small-cell lung cancers, a study by Swiss researchers has found. (Source: MedWire News - Lung Cancer)
Source: MedWire News - Lung Cancer - July 12, 2013 Category: Cancer & Oncology Source Type: news
Vitamin supplementation unnecessary before pemetrexed
The duration of vitamin supplementation before the first dose of pemetrexed does not appear to influence the risk for treatment toxicity in lung cancer patients, a study has found. (Source: MedWire News - Lung Cancer)
Source: MedWire News - Lung Cancer - July 10, 2013 Category: Cancer & Oncology Source Type: news
PNA clamping outperforms standard EGFR mutation detection
Epidermal growth factor receptor mutations can be reliably detected in a range of lung cancer samples using peptic nucleic acid clamping, South Korean researchers report. (Source: MedWire News - Lung Cancer)
Source: MedWire News - Lung Cancer - July 10, 2013 Category: Cancer & Oncology Source Type: news
Ubiquitin enzymes show lung cancer treatment promise
Deubiquitinating enzymes offer a novel target for the treatment of lung cancer through the receptor tyrosine kinase signaling pathway, scientists say. (Source: MedWire News - Lung Cancer)
Source: MedWire News - Lung Cancer - July 3, 2013 Category: Cancer & Oncology Source Type: news
Surrogate markers aid lung cancer trials
Research suggests that surrogate markers for overall survival are acceptable endpoints for clinical trials of chemotherapy and radiotherapy in patients with lung cancer. (Source: MedWire News - Lung Cancer)
Source: MedWire News - Lung Cancer - July 3, 2013 Category: Cancer & Oncology Source Type: news
Gene mutation clustering limited in NSCLC
Gene mutations in patients with non-small-cell lung cancer show some clustering by ethnicity and histology but are not exclusive to patient subgroups, indicates research by an international team. (Source: MedWire News - Lung Cancer)
Source: MedWire News - Lung Cancer - July 2, 2013 Category: Cancer & Oncology Source Type: news
Pre-op chemo timing no advantage in resectable NSCLC
The timing of chemotherapy in relation to surgery does not appear to influence survival in patients with early-stage non-small-cell lung cancer, a randomized trial has found. (Source: MedWire News - Lung Cancer)
Source: MedWire News - Lung Cancer - July 2, 2013 Category: Cancer & Oncology Source Type: news
NSCLC immunization ‘proof of concept’ achieved
Immunization against MAGE-A3 is a feasible adjuvant treatment in patients with resectable non-small-cell lung cancer expressing the tumor-specific antigen, research suggests. (Source: MedWire News - Lung Cancer)
Source: MedWire News - Lung Cancer - July 1, 2013 Category: Cancer & Oncology Source Type: news
Protein expression could guide NSCLC chemotherapy choice
Protein expression analysis is technically possible as a means of guiding chemotherapy decisions in patients with a new diagnosis of advanced non-small-cell lung cancer, US investigators say. (Source: MedWire News - Lung Cancer)
Source: MedWire News - Lung Cancer - July 1, 2013 Category: Cancer & Oncology Source Type: news
Age, node status predict lung cancer surgery survival
Age and node status are the strongest prognostic factors for patients considering T4 lung cancer resection, results from the Japanese Lung Cancer Registry show. (Source: MedWire News - Lung Cancer)
Source: MedWire News - Lung Cancer - June 10, 2013 Category: Cancer & Oncology Source Type: news
Silenced miR points to poor SCLC prognosis
Chinese scientists have identified a molecular marker that significantly predicts the survival of patients with small-cell lung cancer. (Source: MedWire News - Lung Cancer)
Source: MedWire News - Lung Cancer - June 7, 2013 Category: Cancer & Oncology Source Type: news
HER2 screening recommended for lung adenocarcinoma patients
Researchers highlight the importance of testing for HER2 mutations in patients with non-small-cell lung cancer, adding to evidence that supports the use of HER2-targeted drugs in this population. (Source: MedWire News - Lung Cancer)
Source: MedWire News - Lung Cancer - June 6, 2013 Category: Cancer & Oncology Source Type: news
Nicotine-induced changes alter EGFR-TKI efficacy
Japanese scientists have uncovered a mechanism by which smoking reduces the efficacy of epidermal growth factor receptor tyrosine kinase inhibitor therapy in patients with lung cancer. (Source: MedWire News - Lung Cancer)
Source: MedWire News - Lung Cancer - June 4, 2013 Category: Cancer & Oncology Source Type: news
KRAS mutation fails to predict NSCLC chemotherapy success
Research casts doubt on the ability of the KRAS mutation to aid the selection of patients with non-small-cell lung cancer to receive adjuvant chemotherapy. (Source: MedWire News - Lung Cancer)
Source: MedWire News - Lung Cancer - June 3, 2013 Category: Cancer & Oncology Source Type: news
Primary NSCLC shares mutations with metastases
Scientists have found a high level of concordance in the genetic mutations of pairs of primary non-small-cell lung cancer and metachronous or synchronous metastases. (Source: MedWire News - Lung Cancer)
Source: MedWire News - Lung Cancer - June 3, 2013 Category: Cancer & Oncology Source Type: news
