Glimmer of hope for imatinib-resistant GIST
The monoclonal antibody SR1 can significantly inhibit gastrointestinal stromal tumor cell growth, report researchers in the Proceedings of the National Academy of Sciences. (Source: MedWire News - Gastroenterology)
Source: MedWire News - Gastroenterology - February 8, 2013 Category: Gastroenterology Source Type: news

Interferon retreatment warning in HCV
Hepatitis C virus patients who do not respond to interferon should not receive further treatment with the drug, say the authors of a new Cochrane review. (Source: MedWire News - Gastroenterology)
Source: MedWire News - Gastroenterology - February 5, 2013 Category: Gastroenterology Source Type: news

Epidemiology model supports 20:80 transmission rule in HCV
A new hepatitis C virus transmission model combining genetic and epidemiologic data reveals that the majority of transmission of the virus is by a minority of intravenous drug users. (Source: MedWire News - Gastroenterology)
Source: MedWire News - Gastroenterology - February 1, 2013 Category: Gastroenterology Source Type: news

Waist size trumps BMI as Barrett’s esophagus risk factor
Researchers have found that waist circumference independently predicts the risk for Barrett’s esophagus, leading them to dismiss a previously reported association between body mass index and the disease. (Source: MedWire News - Gastroenterology)
Source: MedWire News - Gastroenterology - January 31, 2013 Category: Gastroenterology Source Type: news

Gene variant boosts ulcer susceptibility in NSAID users
A single nucleotide polymorphism in the cytochrome P450 2C gene cluster influences the risk for peptic ulcer disease in people taking non-steroidal anti-inflammatory drugs, a study reveals. (Source: MedWire News - Gastroenterology)
Source: MedWire News - Gastroenterology - January 31, 2013 Category: Gastroenterology Source Type: news

ALDH1 expression predicts outcome in node-negative rectal cancer
Expression of the cancer stem cell marker aldehyde dehydrogenase 1 is an independent predictor for poor prognosis in node-negative rectal cancer, researchers say. (Source: MedWire News - Gastroenterology)
Source: MedWire News - Gastroenterology - January 30, 2013 Category: Gastroenterology Source Type: news

Sydney 2012 norovirus strain continues to spread globally
A new strain of norovirus known as Sydney 2012 has caused a significant number of acute outbreaks of the infection during the 2012–2013 winter season and continues to spread worldwide. (Source: MedWire News - Gastroenterology)
Source: MedWire News - Gastroenterology - January 30, 2013 Category: Gastroenterology Source Type: news

Shorter surveillance intervals detect HCC earlier
Hepatocellular carcinoma surveillance in at-risk patients at intervals of less than 6 months picks up smaller tumors compared with longer intervals, show two recently published studies. (Source: MedWire News - Gastroenterology)
Source: MedWire News - Gastroenterology - January 29, 2013 Category: Gastroenterology Source Type: news

Cancer risk independent of folic acid supplementation
Folic acid supplementation does not increase or decrease the risk for cancer, suggests research published in The Lancet. (Source: MedWire News - Gastroenterology)
Source: MedWire News - Gastroenterology - January 28, 2013 Category: Gastroenterology Source Type: news

Children with eczema have distinct gut microbiome
Infants with eczema have more diverse total gut microbiota than those without the skin condition, show study findings. (Source: MedWire News - Gastroenterology)
Source: MedWire News - Gastroenterology - January 25, 2013 Category: Gastroenterology Source Type: news

Simple urine test picks up mesalamine non-adherence
A readily available urine test could identify ulcerative colitis patients who are non-adherent to their mesalamine therapy, research shows. (Source: MedWire News - Gastroenterology)
Source: MedWire News - Gastroenterology - January 24, 2013 Category: Gastroenterology Source Type: news

Efficacy of docusate called into question
Docusate does not significantly improve the management of constipation in hospice patients, show the results of a randomized, placebo-controlled trial. (Source: MedWire News - Gastroenterology)
Source: MedWire News - Gastroenterology - January 23, 2013 Category: Gastroenterology Source Type: news

VRAM flap success for dorsal vaginal and perineal reconstruction
Reconstruction of the dorsal vagina or perineum using the vertical rectus abdominus myocutaneous flap following extensive surgery and intraoperative radiotherapy for rectal cancer results in favorable surgical and quality of life outcomes, research shows. (Source: MedWire News - Gastroenterology)
Source: MedWire News - Gastroenterology - January 23, 2013 Category: Gastroenterology Source Type: news

Tattooing poses HCV risk
Hepatitis C virus infection is more common in people who have had a tattoo, research shows. (Source: MedWire News - Gastroenterology)
Source: MedWire News - Gastroenterology - January 22, 2013 Category: Gastroenterology Source Type: news

Donor feces more effective than antibiotic for C. difficile infection
Treatment of recurrent Clostridium difficile infection with donor feces infusion is significantly more effective than conventional vancomycin therapy, show results published in The New England Journal of Medicine. (Source: MedWire News - Gastroenterology)
Source: MedWire News - Gastroenterology - January 18, 2013 Category: Gastroenterology Source Type: news