Phase III REACH2 Study Demonstrates Significant Improvements from Ruxolitinib Therapy
Data from the phase III REACH2 study indicated that ruxolitinib therapy led to significant improvements in efficacy outcomes in patients with steroid-refractory acute graft-versus-host disease. (Source: CancerNetwork)
Source: CancerNetwork - April 27, 2020 Category: Cancer & Oncology Authors: Hannah Slater Source Type: news

Complications to Continuing Clinical Trials During the COVID-19 Pandemic
New clinical trial practices specific to cancer include new risk assessment strategies, decentralized and remote trial coordination, data collection, and delegation of specific therapeutic activities. (Source: CancerNetwork)
Source: CancerNetwork - April 27, 2020 Category: Cancer & Oncology Authors: Hannah Slater Source Type: news

Updated Interim Data from Phase I Trial of STRO-002 Show Promise in Ovarian Cancer
Encouraging interim data were reported from the ongoing phase I clinical trial of STRO-002 regarding safety and anti-tumor activity results in heavily pre-treated patients with ovarian cancer. (Source: CancerNetwork)
Source: CancerNetwork - April 27, 2020 Category: Cancer & Oncology Authors: Hannah Slater Source Type: news

Kidney Cancer Destination Could Guide Treatment Decisions Moving Forward
A recent study examined pancreatic metastases to understand why patients with this particular kidney cancer have better prognoses, and sought to characterize the clinical behavior, therapeutic implications, and underlying biology of this type of cancer. (Source: CancerNetwork)
Source: CancerNetwork - April 27, 2020 Category: Cancer & Oncology Authors: Matthew Fowler Source Type: news

Improved Survival with Adjuvant Chemoendocrine Therapy in HR+/ERBB2+ Tumors
As prospective clinical trials continue to accrue data, the researchers indicated that this data may help clinicians in decision-making regarding adjuvant systemic therapy for patients with small HR-positive, ERBB2-positive breast cancers. (Source: CancerNetwork)
Source: CancerNetwork - April 26, 2020 Category: Cancer & Oncology Authors: Hannah Slater Source Type: news

Phase II Study of Pembrolizumab Finds Activity in Brain Metastases from NSCLC
The study found that pembrolizumab has activity in brain metastases from non-small cell lung cancer that is similar to its systemic activity and can result in prolonged survival in a subset of patients. (Source: CancerNetwork)
Source: CancerNetwork - April 26, 2020 Category: Cancer & Oncology Authors: Hannah Slater Source Type: news

Comparison of Drugs in the Metastatic and Adjuvant Settings
This study found a substantial difference in the number of agents available for use in the metastatic and adjuvant settings for non-small cell lung cancer, breast cancer, and colon cancer. (Source: CancerNetwork)
Source: CancerNetwork - April 25, 2020 Category: Cancer & Oncology Authors: Hannah Slater Source Type: news

Infection Rate May Indicate a Future Diagnosis of Cancer
In this study, researchers found data that suggested immune suppression and increased infection could occur during the precancerous period. (Source: CancerNetwork)
Source: CancerNetwork - April 25, 2020 Category: Cancer & Oncology Authors: Hannah Slater Source Type: news

Young Adults with Cancer History More Likely to Use and Report Usage of Electronic Cigarettes
This study examined electronic cigarette usage among young adults with a history of cancer, comparing the data to young adults without a history of cancer via the 2018 Behavioral Risk Factor Surveillance System survey. (Source: CancerNetwork)
Source: CancerNetwork - April 24, 2020 Category: Cancer & Oncology Authors: Matthew Fowler Source Type: news

Safe and Healthy Nutritional Practices to Follow During the COVID-19 Pandemic
Rachel Wong, RD, SCO, LD, an outpatient oncology dietician at Georgetown Lombardi Comprehensive Cancer Center, discussed nutrition practices that patients with cancer can follow to remain healthy during the COVID-19 pandemic. (Source: CancerNetwork)
Source: CancerNetwork - April 24, 2020 Category: Cancer & Oncology Authors: Hannah Slater Source Type: news

Positive Results from Phase III PROfound Trial of Olaparib Demonstrate Improvements in OS
Results from the trial showed a statistically significant and clinically meaningful improvement in overall survival with olaparib versus enzalutamide or abiraterone in men with metastatic castration-resistant prostate cancer selected for BRCA1/2 or ATM gene mutations. (Source: CancerNetwork)
Source: CancerNetwork - April 24, 2020 Category: Cancer & Oncology Authors: Hannah Slater Source Type: news

Risk of Breast Cancer in Latinas May Be Due to Subtype-Specific Genetic Risk Variants
This study observed a positive association between Indigenous American genetic ancestry and HER2-positive breast cancer, suggesting that the high incidence of HER2-positive subtypes in Latinas may be due to population and subtype-specific genetic risk variants. (Source: CancerNetwork)
Source: CancerNetwork - April 24, 2020 Category: Cancer & Oncology Authors: Hannah Slater Source Type: news

Analysis of Stage I EFHWTs Treatment Finds Event-Free Survival and Overall Survival Rates Greater Than 95%
A recent study reported a 96.2% event-free survival rate and a 100% overall survival rate when investigating treatment option for stage I epithelial-predominant favorable-histology Wilms tumors in a population with a majority of patients under the age of 48 months. (Source: CancerNetwork)
Source: CancerNetwork - April 23, 2020 Category: Cancer & Oncology Authors: Matthew Fowler Source Type: news

Brendan F. Kennedy, PhD, on a New Imaging Technique for Breast Cancer
Brendan F. Kennedy, PhD, discussed this study which evaluated the accuracy of quantitative micro-elastography compared to optical coherence tomography. (Source: CancerNetwork)
Source: CancerNetwork - April 23, 2020 Category: Cancer & Oncology Authors: Hannah Slater Source Type: news

Rapid Rollout of Telemedicine Aids Cancer Care During COVID-19 Pandemic
Clinicians from Lombardi Comprehensive Cancer Center spoke about moving cancer care to telehealth due to the COVID-19 pandemic. (Source: CancerNetwork)
Source: CancerNetwork - April 23, 2020 Category: Cancer & Oncology Authors: Hannah Slater Source Type: news