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Hepatitis B and the surgeon
Shailesh Sable, Aabha NagralHepatitis B Annual 2011 8(1):17-31Hepatitis B virus is the most transmissible virus and is very resistant to heat and chemicals, because of its unique structure. Blood has the maximum concentration of the virus among all the body fluids and the risk of transmission is related to the presence of HBeAg and the Hepatitis B virus DNA level in the blood. In India, about 1-10% of the healthcare workers are HBsAg positive. Healthcare workers, especially surgeons, and laboratory technicians are at a high risk of developing Hepatitis B infection. Transmission from Hepatitis B positive surgeons to ...
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - September 7, 2016 Category: Hematology Authors: Shailesh Sable Aabha Nagral Source Type: research

Intrafamilial occurrence of hepatitis B virus (HBV) infection and the profile of liver disease in close relatives of patients with HBV infection
Conclusion: The occurrence of hepatitis B positivity among family members of HBsAg-positive patients was 14.53% in our study. This prevalence was twenty-eight times more than the community prevalence of HBV infection in our population, which was earlier found to be 0.52% by our group. Brothers and sisters were the most commonly affected group, as against mothers who were positive for HBsAg, only 11.3%. Hence, the infection among siblings and parents may also be due to horizontal transmission. Index cases of 16.79% were totally reluctant for family screening due to various reasons like social sti...
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - September 7, 2016 Category: Hematology Authors: R Kavitha K Sunil Kumar K Sandesh TM Ramachandran Thomas Varghese Source Type: research

Editorial
Shivaram Prasad SinghHepatitis B Annual 2011 8(1):1-3 (Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1))
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - September 7, 2016 Category: Hematology Authors: Shivaram Prasad Singh Source Type: research

Patient physician interaction
Gourdas ChoudhuriHepatitis B Annual 2010 7(1):86-93Effective interaction and communication between doctor and patient is a central clinical function that cannot be delegated. Besides, the information and evidence which is generated by a proper interaction and communication, to individualize and tailor the treatment for each patient of Hepatitis B, the way patients' perceive their connection with their physician significantly influences their sense of satisfaction and level of concern about their health. A good effective, empathic physician-patient communication leads to improved patient compliance, better clinical o...
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - August 4, 2015 Category: Hematology Authors: Gourdas Choudhuri Source Type: research

HBV therapeutic end points
Anil AroraHepatitis B Annual 2010 7(1):73-85Chronic hepatitis B [CHB] is a major health problem especially in developing countries. Defining the end point of therapy is a key issue in management of CHB patients, since a judicious balance has to be maintained between containing the virus and its sequelae and futility of continuation of therapy beyond a point. The major goals of antiviral therapy are to prevent the complications of CHB such as the development of liver cirrhosis, liver failure, HCC and death. Major advances have been made in the treatment of chronic hepatitis B, which led to significant improvements in the ma...
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - August 4, 2015 Category: Hematology Authors: Anil Arora Source Type: research

Treatment options for HBV with co-morbid conditions
AK SethHepatitis B Annual 2010 7(1):57-72The treatment for Hepatitis B viral infection without any co-morbidities is relatively simpler, although the outcome remains suboptimal. However in a large number of these patients, the matter is complicated by co-morbid conditions which exist in these patients and the treatment in such patients has to be tailored to individual settings and demands. All patients of chronic hepatitis B [CHB] must be evaluated for co-morbidities especially those which can complicate treatment. This overview attempts to provide clinicians with guidance for treatment of CHB patients who have coexisting ...
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - August 4, 2015 Category: Hematology Authors: AK Seth Source Type: research

Selection of treatment options in the management of chronic Hepatitis B
Deepak AmarapurkarHepatitis B Annual 2010 7(1):45-56There has been considerable progress in the treatment of hepatitis B in the past two decades. However, currently approved treatments have significant limitations, and the long-term management of patients with chronic HBV infection is as much an art as a science. Selection of the optimal treatment option is very important in the treatment of chronic hepatitis B. In this review, the focus is on current treatment strategies of chronic hepatitis B (Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1))
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - August 4, 2015 Category: Hematology Authors: Deepak Amarapurkar Source Type: research

Indications for treatment: Whom to treat and whom not to treat!
RK DhimanHepatitis B Annual 2010 7(1):28-44Despite the development of an effective vaccine, Hepatitis B virus (HBV) infection remains a major public health problem worldwide with a significant proportion of chronic HBV infected patients developing liver cirrhosis, liver failure, and primary hepatocellular carcinoma (HCC). Chronic hepatitis B is one of the 10 major causes of death worldwide. Although a number of antiviral agents against HBV are now available, proper selection of patients who would be ideal candidates for therapy is essential. The rationale for treatment is to reduce the risk of progressive chronic liver dis...
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - August 4, 2015 Category: Hematology Authors: RK Dhiman Source Type: research

Goals of therapy in patients with CHB
Ajay DusejaHepatitis B Annual 2010 7(1):16-27Despite the development of a number of antiviral agents for treatment of Chronic Hepatitis B, the treatment of chronic hepatitis B continues to be a challenge for physicians due to the high burden of the disease and the limited efficacy of available therapy. The primary goal of treatment is to eliminate or suppress HBV in order to decrease pathogenicity and infectivity, and reduce hepatic necroinflammation. Clinically, the short-term goal of treatment is to reduce hepatic activity, to prevent the development of hepatic decompensation, to ensure loss of HBeAg (with seroconversion...
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - August 4, 2015 Category: Hematology Authors: Ajay Duseja Source Type: research

Screening for chronic Hepatitis B
KT ShenoyHepatitis B Annual 2010 7(1):5-15Hepatitis B virus (HBV) infection is a major public health problem worldwide. More than 2 billion people have been infected; more than 350 million present with chronic HBV infection. A significant proportion (15-40%) of chronic HBV infected patients develop liver cirrhosis, liver failure, and primary hepatocellular carcinoma (HCC), making chronic hepatitis B one of the 10 major causes of death worldwide. The practice of preventive medicine involves three primary tasks: Screening, counseling, and immunization or chemoprophylaxis. Screening healthy individuals incurs an ethica...
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - August 4, 2015 Category: Hematology Authors: KT Shenoy Source Type: research

Editorial
Shivaram Prasad SinghHepatitis B Annual 2010 7(1):1-4 (Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1))
Source: Table of Contents : Hepatitis B Annual : 2004 - 1(1) - August 4, 2015 Category: Hematology Authors: Shivaram Prasad Singh Source Type: research