Judgment post ‐stratification in finite mixture modeling: An example in estimating the prevalence of osteoporosis
Judgment post ‐stratification is used to supplement observations taken from finite mixture models with additional easy to obtain rank information and incorporate it in the estimation of model parameters. To do this, sampled units are post‐stratified on ranks by randomly selecting comparison sets for each unit from the underlying population and assigning ranks to them using available auxiliary information or judgment ranking. This results in a set of independent order statistics from the underlying model, where the number of units in each rank class is random. We consider cases where one or more rankers with different r...
Source: Statistics in Medicine - September 27, 2018 Category: Statistics Authors: Sedigheh Omidvar, Mohammad Jafari Jozani, Nader Nematollahi Tags: RESEARCH ARTICLE Source Type: research

Nonparametric collective spectral density estimation with an application to clustering the brain signals
Statistics in Medicine, EarlyView. (Source: Statistics in Medicine)
Source: Statistics in Medicine - September 27, 2018 Category: Statistics Authors: Mehdi Maadooliat, Ying Sun, Tianbo Chen Source Type: research

Adaptive protocols based on predictions from a mechanistic model of the effect of IL7 on CD4 counts
In human immunodeficiency virus –infected patients, antiretroviral therapy suppresses the viral replication, which is followed in most patients by a restoration of CD4+ T cells pool. For patients who fail to do so, repeated injections of exogenous interleukin 7 (IL7) are experimented. The IL7 is a cytokine that is involved in th e T cell homeostasis and the INSPIRE study has shown that injections of IL7 induced a proliferation of CD4+ T cells. Phase I/II INSPIRE 2 and 3 studies have evaluated a protocol in which a first cycle of three IL7 injections is followed by a new cycle at each visit when the patient has less than ...
Source: Statistics in Medicine - September 26, 2018 Category: Statistics Authors: Laura Villain, Daniel Commenges, Chlo é Pasin, Mélanie Prague, Rodolphe Thiébaut Tags: RESEARCH ARTICLE Source Type: research

Respondent ‐driven sampling and the homophily configuration graph
Respondent ‐Driven Sampling (RDS) is a popular method for surveying hard‐to‐reach populations, especially in the public health domain. Adjusting for the complex sampling mechanism of the RDS procedure is challenging. We propose a new model for the RDS mechanism motivated by a graph model, which we call t he Homophily Configuration Graph. Under this model, we develop a new estimator for population proportions that is robust to seed bias, differential activity, differential recruitment and short recruitment chains. We also connect it to existing RDS theory by showing that, if the sample fraction is sm all, our estimato...
Source: Statistics in Medicine - September 26, 2018 Category: Statistics Authors: Ian E. Fellows Tags: RESEARCH ARTICLE Source Type: research

Nonparametric collective spectral density estimation with an application to clustering the brain signals
In this paper, we develop a method for the simultaneous estimation of spectral density functions (SDFs) for a collection of stationary time series that share some common features. Due to the similarities among the SDFs, the log ‐SDF can be represented using a common set of basis functions. The basis shared by the collection of the log‐SDFs is estimated as a low‐dimensional manifold of a large space spanned by a prespecified rich basis. A collective estimation approach pools information and borrows strength across the SDFs to achieve better estimation efficiency. Moreover, each estimated spectral density has a concise...
Source: Statistics in Medicine - September 26, 2018 Category: Statistics Authors: Mehdi Maadooliat, Ying Sun, Tianbo Chen Tags: RESEARCH ARTICLE Source Type: research

Multiple mediation analysis with survival outcomes: With an application to explore racial disparity in breast cancer survival
Statistics in Medicine, EarlyView. (Source: Statistics in Medicine)
Source: Statistics in Medicine - September 26, 2018 Category: Statistics Authors: Qingzhao Yu, Xiaocheng Wu, Bin Li, Richard A. Scribner Source Type: research

Adaptive protocols based on predictions from a mechanistic model of the effect of IL7 on CD4 counts
Statistics in Medicine, EarlyView. (Source: Statistics in Medicine)
Source: Statistics in Medicine - September 26, 2018 Category: Statistics Authors: Laura Villain, Daniel Commenges, Chlo é Pasin, Mélanie Prague, Rodolphe Thiébaut Source Type: research

Respondent ‐driven sampling and the homophily configuration graph
Statistics in Medicine, EarlyView. (Source: Statistics in Medicine)
Source: Statistics in Medicine - September 26, 2018 Category: Statistics Authors: Ian E. Fellows Source Type: research

Multiple mediation analysis with survival outcomes: With an application to explore racial disparity in breast cancer survival
Mediation analysis allows the examination of effects of a third variable in the pathway between an exposure and an outcome. The general multiple mediation analysis method, proposed by Yu et al, improves traditional methods (eg, estimation of natural and controlled direct effects) to enable consideration of multiple mediators/confounders simultaneously and the use of linear and nonlinear predictive models for estimating mediation/confounding effects. In this paper, we extend the method for time ‐to‐event outcomes and apply the method to explore the racial disparity in breast cancer survivals. Breast cancer is the most c...
Source: Statistics in Medicine - September 25, 2018 Category: Statistics Authors: Qingzhao Yu, Xiaocheng Wu, Bin Li, Richard A. Scribner Tags: RESEARCH ARTICLE Source Type: research

Retraction: Lu, T. Bayesian inference on mixed ‐effects location scale models with skew‐t distribution and mismeasured covariates for longitudinal data. Statist. Med. 2017;36:2614–2629. doi: 10.1002/sim.7315
Statistics in Medicine, EarlyView. (Source: Statistics in Medicine)
Source: Statistics in Medicine - September 25, 2018 Category: Statistics Source Type: research

A Bayesian approach for correcting exposure misclassification in meta ‐analysis
Statistics in Medicine, EarlyView. (Source: Statistics in Medicine)
Source: Statistics in Medicine - September 25, 2018 Category: Statistics Authors: Qinshu Lian, James S. Hodges, Richard MacLehose, Haitao Chu Source Type: research

A Bayesian approach for correcting exposure misclassification in meta ‐analysis
In observational studies, misclassification of exposure is ubiquitous and can substantially bias the estimated association between an outcome and an exposure. Although misclassification in a single observational study has been well studied, few papers have considered it in a meta ‐analysis. Meta‐analyses of observational studies provide important evidence for health policy decisions, especially when large randomized controlled trials are unethical or unavailable. It is imperative to account properly for misclassification in a meta‐analysis to obtain valid point and int erval estimates. In this paper, we propose a nov...
Source: Statistics in Medicine - September 24, 2018 Category: Statistics Authors: Qinshu Lian, James S. Hodges, Richard MacLehose, Haitao Chu Tags: RESEARCH ARTICLE Source Type: research

Estimating heterogeneous treatment effects for latent subgroups in observational studies
Statistics in Medicine, EarlyView. (Source: Statistics in Medicine)
Source: Statistics in Medicine - September 20, 2018 Category: Statistics Authors: Hang J.Kim , BoLu , Edward J.Nehus , Mi ‐OkKim Source Type: research

Rank ‐based inference for covariate and group effects in clustered data in presence of informative intra‐cluster group size
Statistics in Medicine, EarlyView. (Source: Statistics in Medicine)
Source: Statistics in Medicine - September 20, 2018 Category: Statistics Authors: SandipanDutta , SomnathDatta Source Type: research

Estimating heterogeneous treatment effects for latent subgroups in observational studies
Statistics in Medicine, EarlyView. (Source: Statistics in Medicine)
Source: Statistics in Medicine - September 20, 2018 Category: Statistics Authors: Hang J.Kim , BoLu , Edward J.Nehus , Mi ‐OkKim Source Type: research