Prescription patterns of antihyperglycemic drugs in elderly patients in Spain: A national cross-sectional study
ConclusionsElderly patients with type 2 diabetes often receive antihyperglycemic therapy with higher risk of hypoglycemia. Substitution of secretagogues and human insulin therapy for safer medication could significantly reduce the adverse effects of diabetes treatment in this population.ResumenAntecedentes y objetivosLos pacientes ancianos con diabetes tipo 2 constituyen un grupo heterogéneo y creciente de sujetos en el que los objetivos terapéuticos y las prescripciones de los fármacos antihiperglucemiantes deben adaptarse a las enfermedades coexistentes y a su situación funcional y social.MétodosRealizamos un estudi...
Source: Revista Clinica Espanola - August 15, 2019 Category: Internal Medicine Source Type: research
Initiation, maintenance and withdrawal of disease-modifying treatment during an acute heart failure decompensation
Publication date: Available online 8 August 2019Source: Revista Clínica Española (English Edition)Author(s): J.C. Trullàs, F. Formiga, J. Casado, A. González-Franco (Source: Revista Clinica Espanola)
Source: Revista Clinica Espanola - August 9, 2019 Category: Internal Medicine Source Type: research
PCSK9 inhibitors: Ratification of the role of LDL cholesterol in cardiovascular prevention. Towards a convergence of European and North American prevention guidelines?
Publication date: Available online 1 August 2019Source: Revista Clínica Española (English Edition)Author(s): C. Guijarro, M. CamafortAbstractThe epidemiological association of cholesterol associated with low density lipoproteins (LDL-c) levels and the development of atherosclerotic vascular disease has been ratified by mendelian randomization studies. Paradoxically, the success of statins led to the underestimation of other lipid-lowering therapies and even the measurement of LDL-c. Recent studies show that the reduction of LDL-c to extraordinarily low levels through absorption inhibition, and, in a particularly intensiv...
Source: Revista Clinica Espanola - August 2, 2019 Category: Internal Medicine Source Type: research
Hip fracture co-management in the elderly in a tertiary referral hospital: A cohorts study
ConclusionsCo-management for elderly patients admitted with hip fracture provides a better information about previously chronic conditions, a higher control of hospital complications and decreases hospital mortality.ResumenIntroducciónLa fractura de cadera del anciano es de los diagnósticos más prevalentes en los servicios de Traumatología, con gran impacto en términos clínicos, económicos y sociales. Nuestro objetivo es analizar el impacto clínico de un modelo de comanejo entre Traumatología y Medicina Interna para pacientes ancianos ingresados por fractura de cadera en un hospital de tercer nivel.Material y mét...
Source: Revista Clinica Espanola - July 31, 2019 Category: Internal Medicine Source Type: research
Is oxidative stress associated with disease severity, pulmonary function and metabolic syndrome in chronic obstructive pulmonary disease?
ConclusionCOPD severity, worse pulmonary function and presence of metabolic syndrome are associated with oxidative stress in individuals with COPD.ResumenObjetivoInvestigar las asociaciones entre los biomarcadores oxidantes/antioxidantes y el estado de gravedad, la función pulmonar y la presencia de síndrome metabólico (SM) en pacientes con EPOC.MétodosSe incluyeron 74 sujetos, 39 con EPOC (edad 69 ± 7 años; mujeres 41%) y 35 para el grupo control (edad 69 ± 7 años; mujeres: 43%). Fueron diagnosticados con SM y asignados a uno de los 4 subgrupos: EPOC y control, con y sin SM, respectivamente. Se...
Source: Revista Clinica Espanola - July 28, 2019 Category: Internal Medicine Source Type: research
Impact of an intervention program to improve potentially inappropriate prescription in hospitalized elderly patients
ConclusionsReview of medication in elderly patients, along with the use of tools that help in the identification of dangerous drugs, entail a reduction of inadequate prescription and significantly contribute to the continuous improvement of chronic medication in elders.ResumenIntroducción y objetivosLa prescripción potencialmente inapropiada (PPI) es frecuente en ancianos. Se ha convertido en un problema de salud pública mundial por su relación con efectos adversos a medicamentos (EAM), aumento de la morbimortalidad, visitas a urgencias y consumo de recursos. El objetivo principal de este estudio fue determinar si el u...
Source: Revista Clinica Espanola - July 28, 2019 Category: Internal Medicine Source Type: research
Terry’s nails as the first clinical sign of autoimmune hepatitis
Publication date: Available online 18 July 2019Source: Revista Clínica Española (English Edition)Author(s): F.J. Navarro-Triviño, L. Linares-González, T. Ródenas-Herranz (Source: Revista Clinica Espanola)
Source: Revista Clinica Espanola - July 19, 2019 Category: Internal Medicine Source Type: research
Sarcoidosis and massive splenomegaly: a diagnostic dilemma
Publication date: Available online 18 July 2019Source: Revista Clínica Española (English Edition)Author(s): C. Peña Arce, Ó. Vázquez Gómez, F. Merino Morales, C. Diego Hernández (Source: Revista Clinica Espanola)
Source: Revista Clinica Espanola - July 19, 2019 Category: Internal Medicine Source Type: research
NOVICA: Characteristics and outcomes of patients who have a first episode of heart failure (de novo)
ConclusionsPatients admitted to hospital emergency departments for NOAHF show a different clinical profile from patients with CDHF. In the adjusted analysis, there were no differences between the 2 groups regarding hospital mortality, 30-day mortality or 12-month mortality.ResumenAntecedentes y objetivosDescribir las características clínicas y el pronóstico-mortalidad intrahospitalaria, a 30 días y a 12 meses y reconsulta en urgencias a 30 días por insuficiencia cardiaca aguda-de pacientes atendidos en servicios de urgencias hospitalarios por insuficiencia cardiaca aguda de nueva aparición o de novo (ICAN) y comparar...
Source: Revista Clinica Espanola - July 19, 2019 Category: Internal Medicine Source Type: research
Social and clinical predictors associated with prolonged hospital stays for patients with severe exacerbation of chronic obstructive pulmonary disease
ConclusionsVariables related to the social sphere play a relevant role in hospital stays, as do the impact of the disease and the persistent use of tobacco by patients with severe COPD exacerbation.ResumenObjetivoAnalizar si existen factores sociales que influyan en la estancia hospitalaria prolongada (EHP) de pacientes con agudización grave de EPOC (AEPOC), además de factores clínico-demográficos.MetodologíaEstudio de cohortes prospectivo. Se incluyeron pacientes consecutivos que ingresaron por AEPOC en un servicio de Neumología. Se registraron variables demográficas, clínicas (tabaquismo, exacerbaciones e infecci...
Source: Revista Clinica Espanola - June 29, 2019 Category: Internal Medicine Source Type: research
The importance of evaluating fragility and dependence
Publication date: Available online 26 June 2019Source: Revista Clínica Española (English Edition)Author(s): J. Marco Martínez, S. Plaza Canteli (Source: Revista Clinica Espanola)
Source: Revista Clinica Espanola - June 27, 2019 Category: Internal Medicine Source Type: research
Is the trabecular bone score useful for assessing bone quality in patients with axial spondyloarthritis and syndesmophytes?
ConclusionTrabecular bone scores do not appear to be masked by the presence of syndesmophytes.ResumenIntroducción y objetivosLos sindesmofitos parecen elevar falsamente los valores de densidad mineral ósea lumbar, lo que limita el diagnóstico de osteoporosis por absorciometría de rayos X de doble energía en pacientes con espondiloartritis axial. Por este motivo, el objetivo del estudio fue analizar la influencia de sindesmofitos a nivel lumbar en los valores de puntuación de hueso trabecular y densidad mineral ósea lumbar y cuello femoral, y evaluar los factores clínicos y analíticos asociados a puntuación de hue...
Source: Revista Clinica Espanola - June 27, 2019 Category: Internal Medicine Source Type: research
Haemophagocytic syndrome associated with infections: Not so uncommon
ConclusionsInfection-related HPS must be more common than reported. The geographical environment can influence the triggering infections (in our environment, Leishmania should be considered).ResumenIntroducciónEl síndrome hemofagocítico (SHF) es un trastorno inmunológico grave caracterizado por una inflamación descontrolada con fracaso multiorgánico. Puede estar desencadenado por infecciones víricas, bacterianas, fúngicas o parasitarias. Se describe nuestra experiencia de SHF asociado a infecciones y se estima su incidencia local.Material y métodoEstudio retrospectivo observacional de SHF asociado a infecciones en...
Source: Revista Clinica Espanola - June 24, 2019 Category: Internal Medicine Source Type: research
Multiple peritoneal splenosis mimicking mesenteric metastases in a woman with breast carcinoma
Publication date: Available online 22 June 2019Source: Revista Clínica Española (English Edition)Author(s): Y. Gedikli, F. Guven, G. Ongen, H. Ogul (Source: Revista Clinica Espanola)
Source: Revista Clinica Espanola - June 22, 2019 Category: Internal Medicine Source Type: research
Internal medicine and palliative care: Science and humanism
Publication date: Available online 10 June 2019Source: Revista Clínica Española (English Edition)Author(s): J. Galindo Ocaña, C. Aguilera González (Source: Revista Clinica Espanola)
Source: Revista Clinica Espanola - June 11, 2019 Category: Internal Medicine Source Type: research
