Reply to Dr Costache et al
No abstract available (Source: Regional Anesthesia and Pain Medicine)
Source: Regional Anesthesia and Pain Medicine - October 23, 2017 Category: Anesthesiology Tags: Letters to the Editor Source Type: research

The Clinical Benefits of Ultrasound-Guided Thoracic Epidural Placement
No abstract available (Source: Regional Anesthesia and Pain Medicine)
Source: Regional Anesthesia and Pain Medicine - October 23, 2017 Category: Anesthesiology Tags: Letters to the Editor Source Type: research

Dose-Response Curves for Intrathecal Bupivacaine, Levobupivacaine, and Ropivacaine Given for Labor Analgesia in Nulliparous Women
Conclusions: The results of this study support previous work showing that intrathecal levobupivacaine and ropivacaine are less potent than bupivacaine. Clinical Trial Registration: Chinese Clinical Trial Registry (identifier: ChiCTR-TRC-09000773) and Centre of Clinical Trials Clinical Registry of the Chinese University of Hong Kong (identifier: CUHK_CCT00245). (Source: Regional Anesthesia and Pain Medicine)
Source: Regional Anesthesia and Pain Medicine - October 23, 2017 Category: Anesthesiology Tags: Obstetric Analgesia: Original Article Source Type: research

Bleeding and Neurologic Complications in 58,000 Interventional Pain Procedures
Conclusions: Bleeding complications are rare in patients undergoing low- or intermediate-risk pain procedures even in the presence of antiplatelet medications. This is consistent with recently released guidelines. (Source: Regional Anesthesia and Pain Medicine)
Source: Regional Anesthesia and Pain Medicine - October 23, 2017 Category: Anesthesiology Tags: Chronic and Interventional Pain: Original Articles Source Type: research

Risk Vessels of Retropharyngeal Hematoma During Stellate Ganglion Block
Conclusions: Three-dimensional computed tomography identified the ITA in the medial portion of the ventral surface of the transverse process of the sixth cervical vertebra. The risk vessels of retropharyngeal hematoma during SGB could include the ITA. (Source: Regional Anesthesia and Pain Medicine)
Source: Regional Anesthesia and Pain Medicine - October 23, 2017 Category: Anesthesiology Tags: Chronic and Interventional Pain: Original Articles Source Type: research

The Efficacy of Peripheral Opioid Antagonists in Opioid-Induced Constipation and Postoperative Ileus: A Systematic Review of the Literature
Abstract: Opioid-induced constipation has a negative impact on quality of life for patients with chronic pain and can affect more than a third of patients. A related but separate entity is postoperative ileus, which is an abnormal pattern of gastrointestinal motility after surgery. Nonselective μ-opioid receptor antagonists reverse constipation and opioid-induced ileus but cross the blood-brain barrier and may reverse analgesia. Peripherally acting μ-opioid receptor antagonists target the μ-opioid receptor without reversing analgesia. Three such agents are US Food and Drug Administration approved. We reviewed the litera...
Source: Regional Anesthesia and Pain Medicine - October 23, 2017 Category: Anesthesiology Tags: Chronic and Interventional Pain: Review Article Source Type: research

Pectoral Fascial (PECS) I and II Blocks as Rescue Analgesia in a Patient Undergoing Minimally Invasive Cardiac Surgery
Conclusions: Pectoral nerve blocks have been described in the setting of breast surgery to provide chest wall analgesia. We report the first successful use of Pecs blocks to provide effective chest wall analgesia for a patient undergoing minimally invasive cardiac surgery with thoracotomy. We believe that these blocks may provide an important nonopioid option for the management of pain during recovery from minimally invasive cardiac surgery. (Source: Regional Anesthesia and Pain Medicine)
Source: Regional Anesthesia and Pain Medicine - October 23, 2017 Category: Anesthesiology Tags: Regional Anesthesia and Acute Pain: Case Report Source Type: research

Procaine and Local Anesthetic Toxicity: A Collaboration Between the Clinical and Basic Sciences
This article describes a collaboration beginning in 1928 between Dr John Lundy of the Mayo Clinic and Dr Robert Isenberger of the University of Kansas, which arose from a controversy surrounding systemic adverse reactions to procaine. Isenberger then traveled to the Mayo Clinic to conduct research on various procaine local and spinal anesthesia doses and sodium amytal's protective effect against procaine-induced toxicity. Lundy and Isenberger's work would add to the ongoing discovery of systemic reactions to local anesthetics. (Source: Regional Anesthesia and Pain Medicine)
Source: Regional Anesthesia and Pain Medicine - October 23, 2017 Category: Anesthesiology Tags: Regional Anesthesia and Acute Pain: History Article Source Type: research

Impact of Video Technology for Improving Success of Medial Canthus Episcleral Anesthesia in Ophthalmology
Background and Objectives: Efficient learning of regional anesthesia in ophthalmology remains challenging because trainees are afforded limited opportunity to practice ocular anesthesia. The aim of this prospective, randomized, blinded study was to determine whether teaching with video improves regional anesthesia skills of residents in ophthalmology. Methods: From January to October 2016, 32 novice anesthesiology residents were evaluated while performing medial canthus episcleral procedures during a 5-day rotation. Residents were randomly assigned to either receive or not receive a video review of their performance at da...
Source: Regional Anesthesia and Pain Medicine - October 23, 2017 Category: Anesthesiology Tags: Regional Anesthesia and Acute Pain: Original Articles Source Type: research

Impact of Regional Anesthesia on Recurrence, Metastasis, and Immune Response in Breast Cancer Surgery: A Systematic Review of the Literature
Conclusions: Our study indicates that there are no data to support or refute the use of PVB for reduction of cancer recurrence or improvement in cancer-related survival. However, PVB use is associated with lower levels of inflammation and a better immune response in comparison with general anesthesia and opioid-based analgesia. (Source: Regional Anesthesia and Pain Medicine)
Source: Regional Anesthesia and Pain Medicine - October 23, 2017 Category: Anesthesiology Tags: Regional Anesthesia and Acute Pain: Original Articles Source Type: research

Ultrasound-Guided Regional Anesthesia Simulation Training: A Systematic Review
Conclusions: Ultrasound-guided regional anesthesia knowledge and skills significantly improved with simulation training. The acquired UGRA skills may be transferred to the clinical setting; however, further studies are required to confirm these changes translate to improved patient outcomes. (Source: Regional Anesthesia and Pain Medicine)
Source: Regional Anesthesia and Pain Medicine - October 23, 2017 Category: Anesthesiology Tags: Regional Anesthesia and Acute Pain: Original Articles Source Type: research

Injection Volume and Anesthetic Effect in Serratus Plane Block
Conclusions: Ultrasound-guided serratus plane block spread in the craniocaudal direction is more widespread with 40 mL than with 20 mL of 0.375% ropivacaine. The time until the first postoperative analgesic rescue dose was not extended by a larger volume of injection. Clinical Trials Registration: UMIN Clinical Trials Registry (identifier UMIN000016549). (Source: Regional Anesthesia and Pain Medicine)
Source: Regional Anesthesia and Pain Medicine - October 23, 2017 Category: Anesthesiology Tags: Regional Anesthesia and Acute Pain: Original Articles Source Type: research

Determination of ED50 and ED95 of 0.5% Ropivacaine in Adductor Canal Block to Produce Quadriceps Weakness: A Dose-Finding Study
Background and Objectives: Adductor canal block (ACB) is popular for knee analgesia because of its favorable effect on quadriceps strength. The aim of this study was to find the minimum volume of local anesthetic, which can be injected into the ACB that would result in quadriceps weakness. Methods: This nonrandomized study used an up-and-down sequential allocation design. Twenty-six patients scheduled to undergo arthroscopic knee surgery received an ultrasound-guided ACB preoperatively. The initial volume of ropivacaine 0.5% injected was 30 mL, which was subsequently increased or decreased by 2 mL, depending on whether th...
Source: Regional Anesthesia and Pain Medicine - October 23, 2017 Category: Anesthesiology Tags: Regional Anesthesia and Acute Pain: Original Articles Source Type: research

The Spread of Ultrasound-Guided Injectate From the Adductor Canal to the Genicular Branch of the Posterior Obturator Nerve and the Popliteal Plexus: A Cadaveric Study
Conclusions: Injection of 10 mL of dye into the distal part of the AC spreads into the popliteal fossa and colors the popliteal plexus and the genicular branch of the posterior obturator nerve. (Source: Regional Anesthesia and Pain Medicine)
Source: Regional Anesthesia and Pain Medicine - October 23, 2017 Category: Anesthesiology Tags: Regional Anesthesia and Acute Pain: Original Articles Source Type: research

Psoas Versus Femoral Blocks: A Registry Analysis of Risks and Benefits
Background and Objectives: Psoas blocks are an alternative to femoral nerve blocks and have the potential advantage of blocking the entire lumbar plexus. However, the psoas muscle is located deeply, making psoas blocks more difficult than femoral blocks. In contrast, while femoral blocks are generally easy to perform, the inguinal region is prone to infection. We thus tested the hypothesis that psoas blocks are associated with more insertion-related complications than femoral blocks but have fewer catheter-related infections. Methods: We extracted 22,434 surgical cases from the German Network for Regional Anesthesia regis...
Source: Regional Anesthesia and Pain Medicine - October 23, 2017 Category: Anesthesiology Tags: Regional Anesthesia and Acute Pain: Original Articles Source Type: research