Modulation of CYP3A4 and CYP2C9 activity by Bulbine natalensis and its constituents: An assessment of HDI risk of Bulbine natalensis containing supplements
Publication date: Available online 19 November 2020Source: PhytomedicineAuthor(s): Islam Husain, Vamshi Manda, Manal Alhusban, Olivia R. Dale, Ji-Yeong Bae, Bharathi Avula, Bill J. Gurley, Amar G. Chittiboyina, Ikhlas A. Khan, Shabana I. Khan (Source: Phytomedicine)
Source: Phytomedicine - November 19, 2020 Category: Drugs & Pharmacology Source Type: research

Thepotential LXRβ agonist stigmasterol protects against hypoxia/reoxygenation injury by modulating mitophagy in primary hippocampal neurons
Publication date: Available online 19 November 2020Source: PhytomedicineAuthor(s): Md. Nazmul Haque, Md. Abdul Hannan, Raju Dash, Sung Min Choi, Il Soo Moon (Source: Phytomedicine)
Source: Phytomedicine - November 19, 2020 Category: Drugs & Pharmacology Source Type: research

Naringenin alleviates nonalcoholic steatohepatitis in middle-aged Apoe−/−mice: role of SIRT1
Publication date: Available online 18 November 2020Source: PhytomedicineAuthor(s): Yi Qiao Hua, Yi Zeng, Jin Xu, Xiao Le Xu (Source: Phytomedicine)
Source: Phytomedicine - November 18, 2020 Category: Drugs & Pharmacology Source Type: research

Physcion, a tetra-substituted 9,10-anthraquinone, prevents homocysteine-induced endothelial dysfunction by activating Ca2+- and Akt-eNOS-NO signaling pathways
Publication date: Available online 18 November 2020Source: PhytomedicineAuthor(s): Xiao Wei Ji, Hang Ji Lyu, Guang Hai Zhou, Bo Wu, Yuan Yuan Zhu, Tian Hua Wu, Feng zhang, Song Nan Jin, Kyung Woo Cho, Jin Fu Wen (Source: Phytomedicine)
Source: Phytomedicine - November 18, 2020 Category: Drugs & Pharmacology Source Type: research

2α-Hydroxyalantolactone from Pulicaria undulata: activity against multidrug-resistant tumor cells and modes of action
Publication date: Available online 17 November 2020Source: PhytomedicineAuthor(s): Mohamed-Elamir F. Hegazy, Mona Dawood, Nuha Mahmoud, Mohamed Elbadawi, Yoshikazu Sugimoto, Sabine M. Klauck, Nagla Mohamed, Thomas Efferth (Source: Phytomedicine)
Source: Phytomedicine - November 17, 2020 Category: Drugs & Pharmacology Source Type: research

Nootkatone attenuates myocardial oxidative damage, inflammation and apoptosis by modulating altered TLR4/NF-κB/MAPK signaling and activating PI3K/Nrf2/Akt signaling cascades in β-adrenergic agonist induced myocardial infarction in rats
Publication date: Available online 7 November 2020Source: PhytomedicineAuthor(s): M.F. Nagoor Meeran, Sheikh Azimullah, E Adeghate, Shreesh Ojha (Source: Phytomedicine)
Source: Phytomedicine - November 8, 2020 Category: Drugs & Pharmacology Source Type: research

Effects and Safety of Herbal Medicines among Community-dwelling Residents during COVID-19 Pandemic: A Large Prospective, Randomized Controlled Trial (RCT)
Publication date: Available online 5 November 2020Source: PhytomedicineAuthor(s): Bohua Yan, Zhiwei Jiang, Jing Yuan, Minghui Li, Jieping Zeng, Jianyuan Tang, Kevin Lu, Hong Ding, Jielai Xia, Qiaoling Wang, Jundong Wang, Hongyan Xie, Wenyuan Li, Na Zhang, Haiyan Li, Xiaoya Sang, Lina Wu, Xiaomo Xiong, Shiyun Tang, Yan Li (Source: Phytomedicine)
Source: Phytomedicine - November 6, 2020 Category: Drugs & Pharmacology Source Type: research

Effect and safety of Chinese herbal medicine granules in patients with severe coronavirus disease 2019 in Wuhan, China: a retrospective, single-center study with propensity score matching
Publication date: Available online 5 November 2020Source: PhytomedicineAuthor(s): Yuanyuan Wang, Yuntao Liu, Qingquan Lv, Danwen Zheng, Li Zhou, Wenwei Ouyang, Banghan Ding, Xu Zou, Fang Yan, Bo Liu, Jun Chen, Tianzhu Liu, Chicheng Fu, Qu Fang, Yi Wang, Fang Li, Ailan Chen, Cecilia Stålsby Lundborg, Jianwen Guo, Zehuai Wen (Source: Phytomedicine)
Source: Phytomedicine - November 6, 2020 Category: Drugs & Pharmacology Source Type: research

Synergistic breast cancer suppression efficacy of doxorubicin by combination with glycyrrhetinic acid as an angiogenesis inhibitor
Publication date: Available online 4 November 2020Source: PhytomedicineAuthor(s): Jinfeng Shi, Jingjing Li, Jiaxin Li, Renkai Li, Xiaoping Wu, Fei Gao, Liang Zou, Winston Wing Shum Mak, Chaomei Fu, Jinming Zhang, George Pak-Heng Leung (Source: Phytomedicine)
Source: Phytomedicine - November 5, 2020 Category: Drugs & Pharmacology Source Type: research

Salidroside protects against cardiomyocyte apoptosis and ventricular remodeling by AKT/HO-1 signaling pathways in a diabetic cardiomyopathy mouse model
Publication date: Available online 4 November 2020Source: PhytomedicineAuthor(s): Jing Ni, Yuanmin Li, Yawei Xu, Rong Guo (Source: Phytomedicine)
Source: Phytomedicine - November 5, 2020 Category: Drugs & Pharmacology Source Type: research

A combination of Olea europaea leaf extract and Spirodela polyrhiza extract alleviates atopic dermatitis by modulating immune balance and skin barrier function in a 1-chloro-2,4-dinitrobenzene-induced murine model
Publication date: Available online 5 November 2020Source: PhytomedicineAuthor(s): Young-Sil Lee, Hyung Won Ryu, Won-Kyung Yang, Mi Hyeon Park, Yang-Chun Park, Doo-Young Kim, Hyuk Joon Kwon, Soo-Young Kim, Sei-Ryang Oh, Seung-Hyung Kim (Source: Phytomedicine)
Source: Phytomedicine - November 5, 2020 Category: Drugs & Pharmacology Source Type: research

Protection against chemotherapy- and radiotherapy-induced side effects: A review based on the mechanisms and therapeutic opportunities of phytochemicals
Publication date: Available online 31 October 2020Source: PhytomedicineAuthor(s): Yong-Qiang Liu, Xiao-Lu Wang, Dan-Hua He, Yong-Xian Cheng (Source: Phytomedicine)
Source: Phytomedicine - November 1, 2020 Category: Drugs & Pharmacology Source Type: research

Oleanolic acid protects against mast cell-mediated allergic responses by suppressing Akt/NF-κB and STAT1 activation
Publication date: January 2021Source: Phytomedicine, Volume 80Author(s): Yun-Mi Kang, Minho Lee, Hyo-Jin An (Source: Phytomedicine)
Source: Phytomedicine - October 30, 2020 Category: Drugs & Pharmacology Source Type: research

Celastrol ameliorates Propionibacterium acnes/LPS-induced liver damage and MSU-induced gouty arthritis via inhibiting K63 deubiquitination of NLRP3
Publication date: January 2021Source: Phytomedicine, Volume 80Author(s): Chang-Yu Yan, Shu-Hua Ouyang, Xi Wang, Yan-Ping Wu, Wan-Yang Sun, Wen-Jun Duan, Lei Liang, Xiang Luo, Hiroshi Kurihara, Yi-Fang Li, Rong-Rong He (Source: Phytomedicine)
Source: Phytomedicine - October 30, 2020 Category: Drugs & Pharmacology Source Type: research

Network pharmacology, molecular docking integrated surface plasmon resonance technology reveals the mechanism of Toujie Quwen Granules against Coronavirus disease 2019 pneumonia
Publication date: Available online 28 October 2020Source: PhytomedicineAuthor(s): Miaobo Ye, Guiwen Luo, Dexiao Ye, Mengting She, Ning Sun, Yu-Jing Lu, Jie Zheng (Source: Phytomedicine)
Source: Phytomedicine - October 29, 2020 Category: Drugs & Pharmacology Source Type: research