Effects of a Single Dose of Parecoxib on Inflammatory Response and Ischemic Tubular Injury Caused by Hemorrhagic Shock in Rats.
Authors: Takaku M, da Silva AC, Iritsu NI, Vianna PTG, Castiglia YMM Abstract Parecoxib, a selective COX-2 inhibitor, is used to improve analgesia in postoperative procedures. Here we evaluated whether pretreatment with a single dose of parecoxib affects the function, cell injury, and inflammatory response of the kidney of rats subjected to acute hemorrhage. Inflammatory response was determined according to serum and renal tissue cytokine levels (IL-1α, IL-1β, IL-6, IL-10, and TNF-α). Forty-four adult Wistar rats anesthetized with sevoflurane were randomized into four groups: placebo/no hemorrhage (Plc/...
Source: Pain Research and Treatment - March 21, 2018 Category: Anesthesiology Tags: Pain Res Treat Source Type: research

Pain and Stress Response during Intravenous Access in Children with Congenital Adrenal Hyperplasia: Effects of EMLA and Nitrous Oxide Treatment.
Conclusions: EMLA + N2O offers the possibility of improving the intravenous procedure for anxious children with CAH. Although the quality of care was better with N2O treatment, it was not possible to demonstrate that this is a prerequisite for valid 17-OHP measurements. PMID: 29464120 [PubMed] (Source: Pain Research and Treatment)
Source: Pain Research and Treatment - February 24, 2018 Category: Anesthesiology Tags: Pain Res Treat Source Type: research

Chronic Pain and Sleep Disorders in Primary Care.
Conclusion: About a quarter of CP patients suffer from clinical insomnia. The suggested bidirectional relation should be considered during comprehensive assessment and treatment of patients. PMID: 29410915 [PubMed] (Source: Pain Research and Treatment)
Source: Pain Research and Treatment - February 9, 2018 Category: Anesthesiology Tags: Pain Res Treat Source Type: research

Postherpetic Neuralgia and Trigeminal Neuralgia.
Authors: Feller L, Khammissa RAG, Fourie J, Bouckaert M, Lemmer J Abstract Postherpetic neuralgia (PHN) is an unpredictable complication of varicella zoster virus- (VZV-) induced herpes zoster (HZ) which often occurs in elderly and immunocompromised persons and which can induce psychosocial dysfunction and can negatively impact on quality of life. Preventive options for PHN include vaccination of high-risk persons against HZ, early use of antiviral agents, and robust management of pain during the early stage of acute herpes zoster. If it does occur, PHN may persist for months or even years after resolution...
Source: Pain Research and Treatment - January 24, 2018 Category: Anesthesiology Tags: Pain Res Treat Source Type: research

Chronic Pelvic Pain: Assessment, Evaluation, and Objectivation.
Authors: Passavanti MB, Pota V, Sansone P, Aurilio C, De Nardis L, Pace MC Abstract Chronic Pelvic Pain (CPP) and Chronic Pelvic Pain Syndrome (CPPS) have a significant impact on men and women of reproductive and nonreproductive age, with a considerable burden on overall quality of life (QoL) and on psychological, functional, and behavioural status. Moreover, diagnostic and therapeutic difficulties are remarkable features in many patients. Therefore evaluation, assessment and objectivation tools are often necessary to properly address each patient and consequently his/her clinical needs. Here we review the...
Source: Pain Research and Treatment - January 24, 2018 Category: Anesthesiology Tags: Pain Res Treat Source Type: research

The Prevalence of and Factors Associated with Neck, Shoulder, and Low-Back Pains among Medical Students at University Hospitals in Central Saudi Arabia.
Conclusion: MSP among Saudi medical students is high, particularly among those in the clinical years and those with history of trauma and with depressive or psychosomatic symptoms. Medical institutions should be aware of this serious health issue and preventive measures are warranted. PMID: 29238618 [PubMed] (Source: Pain Research and Treatment)
Source: Pain Research and Treatment - December 16, 2017 Category: Anesthesiology Tags: Pain Res Treat Source Type: research

Corrigendum to "The Role of Descending Modulation in Manual Therapy and Its Analgesic Implications: A Narrative Review".
Authors: Vigotsky AD, Bruhns RP Abstract [This corrects the article DOI: 10.1155/2015/292805.]. PMID: 29225969 [PubMed - in process] (Source: Pain Research and Treatment)
Source: Pain Research and Treatment - December 12, 2017 Category: Anesthesiology Tags: Pain Res Treat Source Type: research

Interventional Pain Management in Multidisciplinary Chronic Pain Clinics: A Prospective Multicenter Cohort Study with One-Year Follow-Up.
Conclusions: IPM are seldom prescribed in Portuguese MCPC. Further studies on IPM safety and effectiveness are necessary for clear understanding the role of these techniques in CP management. PMID: 29163990 [PubMed] (Source: Pain Research and Treatment)
Source: Pain Research and Treatment - November 24, 2017 Category: Anesthesiology Tags: Pain Res Treat Source Type: research

Pain Processing and Vegetative Dysfunction in Fibromyalgia: A Study by Sympathetic Skin Response and Laser Evoked Potentials.
Conclusions: LEPs and SSR might contribute to clarifying the peripheral and central nervous system involvement in FM patients. PMID: 29093972 [PubMed] (Source: Pain Research and Treatment)
Source: Pain Research and Treatment - November 4, 2017 Category: Anesthesiology Tags: Pain Res Treat Source Type: research

Palmitoylethanolamide in the Treatment of Failed Back Surgery Syndrome.
CONCLUSIONS: This observational study provides evidence, albeit preliminary, for the efficacy and safety of um-PEA (Normast) as part of a multimodal therapeutic regimen in the treatment of pain-resistant patients suffering from failed back surgery syndrome. PMID: 28875041 [PubMed] (Source: Pain Research and Treatment)
Source: Pain Research and Treatment - September 8, 2017 Category: Anesthesiology Tags: Pain Res Treat Source Type: research

Kinesiophobia, Pain, Muscle Functions, and Functional Performances among Older Persons with Low Back Pain.
CONCLUSION: We can conclude that kinesiophobia predicted mobility and balance in older persons with LBP. Kinesiophobia should be continuously assessed in clinical settings to recognize the obstacles that may affect patient's compliance towards a rehabilitation program in older persons with LBP. PMID: 28634547 [PubMed - in process] (Source: Pain Research and Treatment)
Source: Pain Research and Treatment - June 22, 2017 Category: Anesthesiology Tags: Pain Res Treat Source Type: research

Association between Pain in Adolescence and Low Back Pain in Adulthood: Studying a Cohort of Mine Workers.
Conclusions. There were no clear associations between self-reported pain in adolescence and LBP in adulthood. Self-reported daily ratings of LBP were associated with LBP from the health examination. Possible limitations for this study were the retrospective design and few participants. PMID: 28367328 [PubMed - in process] (Source: Pain Research and Treatment)
Source: Pain Research and Treatment - April 5, 2017 Category: Anesthesiology Tags: Pain Res Treat Source Type: research

Quantitative Thermal Testing Profiles as a Predictor of Treatment Response to Topical Capsaicin in Patients with Localized Neuropathic Pain.
Authors: Serrano A, Torres D, Veciana M, Caro C, Montero J, Mayoral V Abstract There are no reliable predictors of response to treatment with capsaicin. Given that capsaicin application causes heat sensation, differences in quantitative thermal testing (QTT) profiles may predict treatment response. The aim of this study was to determine whether different QTT profiles could predict treatment outcomes in patients with localized peripheral neuropathic pain (PeLNP). We obtained from medical records QTT results and treatment outcomes of 55 patients treated between 2010 and 2013. Warm sensation threshold (WST) a...
Source: Pain Research and Treatment - March 24, 2017 Category: Anesthesiology Tags: Pain Res Treat Source Type: research

iACT-CEL: A Feasibility Trial of a Face-to-Face and Internet-Based Acceptance and Commitment Therapy Intervention for Chronic Pain in Singapore.
Conclusions. An adaptation of ACT for people with chronic pain in Singapore appears promising. Optimal treatment design and more effective ways to target outcomes and processes measured here are required. PMID: 28326196 [PubMed - in process] (Source: Pain Research and Treatment)
Source: Pain Research and Treatment - March 24, 2017 Category: Anesthesiology Tags: Pain Res Treat Source Type: research

Evaluating the Measurement Properties of the Self-Assessment of Treatment Version II, Follow-Up Version, in Patients with Painful Diabetic Peripheral Neuropathy.
Conclusions. The SAT II is a reliable and valid measure for assessing treatment improvement in PDPN patients. PMID: 28191351 [PubMed - in process] (Source: Pain Research and Treatment)
Source: Pain Research and Treatment - February 14, 2017 Category: Anesthesiology Tags: Pain Res Treat Source Type: research