Fast track to health — Intermittent energy restriction in adolescents with obesity. A randomised controlled trial study protocol
This study aims to determine if IER results in lower body mass index (BMI) z-score after 52 weeks in metabolically unhealthy adolescents with obesity compared with continuous energy restriction (CER).Methods/designThis is a prospective, randomised, multi-centre trial conducted in tertiary care settings, with three phases: jumpstart (weeks 0–4); intensive intervention (weeks 5–16); continued intervention and/or maintenance (weeks 17–52). During the jumpstart phase, all participants follow a very low energy diet (∼800 kcal/3350 kJ/day), then transition to their allocated intervention: IER or CER. IER involv...
Source: Obesity Research and Clinical Practice - December 7, 2019 Category: Eating Disorders & Weight Management Source Type: research

A proposed standardized approach to studying attrition in pediatric weight management
Publication date: Available online 7 December 2019Source: Obesity Research & Clinical PracticeAuthor(s): Nicholas D. Spence, Joseph A. Skelton, Geoff D.C. BallAbstractPediatric obesity is a major public health issue. Lifestyle and behavioral interventions are the foundation of pediatric weight management; however, intervention effectiveness is compromised when families (children, youth, and/or parent[s]) discontinue care prematurely. Intervention attrition minimizes the potential health benefits derived from interventions, results in inefficient use of health services resources, and can magnify health disparities. Most att...
Source: Obesity Research and Clinical Practice - December 7, 2019 Category: Eating Disorders & Weight Management Source Type: research

Effect of 8-weeks intensive lifestyle intervention on LDL and HDL subfractions
ConclusionEight weeks of diet and physical activity intervention led to weight and fat mass loss and induced improvement of insulin sensitivity, as well as atheroprotective changes of lipid profile. However, the weight loss associated changes in cholesterol subfractions as cardiovascular risk biomarkers deserve further studies. (Source: Obesity Research and Clinical Practice)
Source: Obesity Research and Clinical Practice - December 3, 2019 Category: Eating Disorders & Weight Management Source Type: research

Contribution of genetic, biochemical and environmental factors on insulin resistance and obesity in Mexican young adults
This study aimed to determine the association between biochemical, genetic and environmental factors in the development of metabolic syndrome (MS), obesity and insulin resistance (IR) in Mexican young adults. Young women and men (n = 6750 between 19.3 ± 2.3 years old) participated in a health promotion program from the Autonomous University of Querétaro, México (SU-Salud program). A sub-sample of 665 participants was taken for the determination of single nucleotide polymorphisms (SNP) rs964184 (APOAV), rs9282541 (ABCA1) and rs1260326 (GCKR), using QuantStudio 12 K Flex Real-Time PCR System. For ...
Source: Obesity Research and Clinical Practice - December 1, 2019 Category: Eating Disorders & Weight Management Source Type: research

A single gestational weight gain recommendation is possible for all classes of pregnant women with obesity
ConclusionThe observed pattern of association was the same for all obese classes, hence evidence supports a possible singular GWG recommendation for all women with obesity, regardless of class. (Source: Obesity Research and Clinical Practice)
Source: Obesity Research and Clinical Practice - November 30, 2019 Category: Eating Disorders & Weight Management Source Type: research

Associations between obesity severity and medical comorbidities for children with obesity in low intensity hospital intervention
ConclusionThe US Preventive Services Task Force has documented the effectiveness of intensive behavioral interventions (>26 contact hours for changes in diet, exercise, screen time) for reducing obesity severity in children. Additional research is required to determine whether more intensive behavioral approaches should be added before a child’s obesity reaches the Class III level of severity in order to prevent medical comorbidities. (Source: Obesity Research and Clinical Practice)
Source: Obesity Research and Clinical Practice - November 30, 2019 Category: Eating Disorders & Weight Management Source Type: research

2-OHOA supplementation reduced adiposity and improved cardiometabolic risk to a greater extent than n-3 PUFA in obese mice
Conclusion2-OHOA supplementation was more effective in reducing adiposity, modulating adipokine secretion and ameliorating cardiometabolic risk than n-3 PUFA. (Source: Obesity Research and Clinical Practice)
Source: Obesity Research and Clinical Practice - November 30, 2019 Category: Eating Disorders & Weight Management Source Type: research

Changes in dietary habits and prevalence of cardiovascular risk factors among school students in Macao, China
ConclusionsThe students’ diet had both favourable and unfavourable changes. The rate of obesity and dyslipidaemia rises, while the situation for students aged 12–14 is more concerning. (Source: Obesity Research and Clinical Practice)
Source: Obesity Research and Clinical Practice - November 27, 2019 Category: Eating Disorders & Weight Management Source Type: research

Influence of increased paternal BMI on pregnancy and child health outcomes independent of maternal effects: A systematic review and meta-analysis
ConclusionOur findings support increased paternal BMI negatively affecting pregnancy and child health outcomes. Future studies must include or adjust for paternal contributions, as the longstanding assumption that only maternal factors are relevant is likely to have considerably confounded prior work. (Source: Obesity Research and Clinical Practice)
Source: Obesity Research and Clinical Practice - November 23, 2019 Category: Eating Disorders & Weight Management Source Type: research

Accuracy of self-reported anthropometric measures — Findings from the Finnish Twin Study
ConclusionsSelf-reported anthropometric measures are reasonably accurate indicators for obesity in large cohort studies. However, the possibility of more similar reporting among MZ pairs should be taken into account in twin studies exploring the heritability of different phenotypes. (Source: Obesity Research and Clinical Practice)
Source: Obesity Research and Clinical Practice - November 22, 2019 Category: Eating Disorders & Weight Management Source Type: research

Abdominal fat distribution measured by ultrasound and aerobic fitness in young Danish men born with low and normal birth weight
Publication date: Available online 19 November 2019Source: Obesity Research & Clinical PracticeAuthor(s): Louise G. Grunnet, Anne-Sofie Q. Lund, Klaus K. Laigaard, Amra Ciric Alibegovic, Rasmus T. Jensen, Nicolai S. Henriksen, Arne Astrup, Allan Vaag, Charlotte BrønsAbstractAbdominal subcutaneous and visceral adipose tissue thickness was examined by ultrasound in 17 men with low birth weight (LBW) and 26 with normal BW control individuals to determine if abdominal obesity in LBW individuals is due to increased visceral or subcutaneous fat mass/thickness, or both. Men born with LBW had an increased waist-to-hip ratio (P ...
Source: Obesity Research and Clinical Practice - November 20, 2019 Category: Eating Disorders & Weight Management Source Type: research

Perceptions of social support for weight loss among patients in primary care
This study examined primary care patients’ experiences with support for weight loss efforts. Adult patients (N = 106) were recruited through primary care clinics and completed an electronic survey pertaining to their weight loss efforts. The majority (76%) received support from their existing social network (e.g., family members, professionals); 59% had used apps and <20% had used social media for support. Findings reveal differences in satisfaction with support between men and women and between support sources, which will be useful for informing weight loss interventions in primary care. (Source: Obesity Researc...
Source: Obesity Research and Clinical Practice - November 17, 2019 Category: Eating Disorders & Weight Management Source Type: research

Effects of weight stigma in news media on physical activity, dietary and weight loss intentions and behaviour
ConclusionsIn people with obesity, exposure to weight-stigmatising media may contribute to increased BMI over time. Larger trials with longer follow-up are needed to confirm these findings. (Source: Obesity Research and Clinical Practice)
Source: Obesity Research and Clinical Practice - November 15, 2019 Category: Eating Disorders & Weight Management Source Type: research

Epicardial fat thickness, but not intraabdominal fat, correlates with intima-media thickness in patients with metabolic syndrome: Epicardial fat and intima-media thickness
Publication date: Available online 10 November 2019Source: Obesity Research & Clinical PracticeAuthor(s): Alberto F. Rubio-Guerra, Carolina Guerrero-García, Ivan Meneses-Acero, Alberto Maceda-Serrano, Daniel R. Benítez-Maldonado, German Vargas-Ayala, Jorge L. Narváez-Rivera (Source: Obesity Research and Clinical Practice)
Source: Obesity Research and Clinical Practice - November 10, 2019 Category: Eating Disorders & Weight Management Source Type: research

Metabolically healthy obesity (MHO) in the Malmö diet cancer study – Epidemiology and prospective risks
ConclusionCompared to MUO individuals, MHO individuals presented with a higher level of physical activity, a more favorable lipid- and glucose profile and a lower prospective risk of total mortality and CV morbidity during 20-years follow-up. Notably, no significant differences could be seen in mortality and CV morbidity risks when comparing MHO subjects to non-obese controls. (Source: Obesity Research and Clinical Practice)
Source: Obesity Research and Clinical Practice - November 9, 2019 Category: Eating Disorders & Weight Management Source Type: research