Neoadjuvant chemo for advanced ovarian cancer opens ‘window of opportunity’ for immunotherapies
Presurgical neoadjuvant chemotherapy (NACT) altered the immune microenvironment in patients with stage IIIC/IV tubo-ovarian high-grade serous carcinoma (HGSC), perhaps enhancing the potential... (Source: Ob.Gyn. News)
Source: Ob.Gyn. News - June 15, 2016 Category: OBGYN Source Type: research

Hormonal maintenance therapy prolonged PFS in LGSC
CHICAGO – Hormonal maintenance therapy after primary treatment was associated with significantly prolonged progression-free survival when compared with surveillance in a retrospective study of women... (Source: Ob.Gyn. News)
Source: Ob.Gyn. News - June 14, 2016 Category: OBGYN Source Type: research

A review of 2015 drug approvals: Safety in pregnancy and lactation
The Food and Drug Administration approved 45 new drugs in 2015. Currently, lesinurad (Zurampic) to treat high blood uric levels associated with gout, is not yet available. Another agent, aripiprazole... (Source: Ob.Gyn. News)
Source: Ob.Gyn. News - June 14, 2016 Category: OBGYN Source Type: research

Childhood cancer survivors face several long-term risks
Chicago – Survivors of childhood cancers face several later risks from treatment, and investigators presented studies evaluating risks in three specific areas – secondary neoplasms, premature... (Source: Ob.Gyn. News)
Source: Ob.Gyn. News - June 12, 2016 Category: OBGYN Source Type: research

Adjuvant AI therapy for breast cancer: 10 years is superior to 5 years
CHICAGO – Extending adjuvant aromatase inhibitor (AI) therapy from 5 years to 10 years further reduces the risk of recurrence and new breast cancer in postmenopausal women treated for early disease,... (Source: Ob.Gyn. News)
Source: Ob.Gyn. News - June 11, 2016 Category: OBGYN Source Type: research

Oral contraceptive efficacy unaffected by dimethyl fumarate
NATIONAL HARBOR, MD. – Delayed-release dimethyl fumarate (DMF) coadministered with norgestimate/ethinyl estradiol, a commonly used progesterone-estrogen combination oral contraceptive, did not alter... (Source: Ob.Gyn. News)
Source: Ob.Gyn. News - June 11, 2016 Category: OBGYN Source Type: research

Prepare early for peer review hearings to avoid negative outcomes
CHICAGO – Being targeted for a peer review can be unnerving for physicians, but proper preparation can help doctors smoothly navigate the process and increase their chances for a favorable... (Source: Ob.Gyn. News)
Source: Ob.Gyn. News - June 10, 2016 Category: OBGYN Source Type: research

Few adverse events linked to flibanserin with self-reported alcohol use
A small number of women reported adverse events related to hypotension and syncope while taking flibanserin and drinking alcohol, an analysis of data from five phase III trials has... (Source: Ob.Gyn. News)
Source: Ob.Gyn. News - June 10, 2016 Category: OBGYN Source Type: research

Lupus may confer higher risk for cervical cancer
LONDON – Women with systemic lupus erythematosus (SLE) have more than twice the risk of developing cervical neoplasia than do women in the general population, according to the results of a large... (Source: Ob.Gyn. News)
Source: Ob.Gyn. News - June 9, 2016 Category: OBGYN Source Type: research

Mental health disorders the leading cause of disease burden for females
Mental health and substance abuse disorders are the leading cause of disease burden among U.S. females and the fourth-leading cause for males, according to the Kaiser Family Foundation. Mental... (Source: Ob.Gyn. News)
Source: Ob.Gyn. News - June 9, 2016 Category: OBGYN Source Type: research

50 years of gynecologic surgery: A large dose of ingenuity, a small dose of controversy
Over the past 50 years, there has been explosive change in gynecologic surgery. Ob.Gyn. News has been at the forefront of capturing and chronicling this paradigm shift in the treatment of the female... (Source: Ob.Gyn. News)
Source: Ob.Gyn. News - June 9, 2016 Category: OBGYN Source Type: research

Postpartum glycemic screening rates are low for women with GDM history
Most women with a history of gestational diabetes mellitus are not receiving recommended glycemic screenings in their first postpartum year. And screening rates vary based on geography, race, and use... (Source: Ob.Gyn. News)
Source: Ob.Gyn. News - June 8, 2016 Category: OBGYN Source Type: research

Obesity in healthy women linked to poor pregnancy and neonatal outcomes
Obese women without chronic disease are at greater risk of pregnancy complications and poor neonatal outcomes than are normal weight women, according to a study published in Obstetrics &... (Source: Ob.Gyn. News)
Source: Ob.Gyn. News - June 8, 2016 Category: OBGYN Source Type: research

Cesarean delivery rates among nulliparous women are lower after guidance
For at least one medical center, the adoption of March 2014 consensus guidelines on cesarean delivery was associated with a significant reduction in the primary C-section rate among nulliparous... (Source: Ob.Gyn. News)
Source: Ob.Gyn. News - June 8, 2016 Category: OBGYN Source Type: research

Gyn. oncologists are in demand for robotic hysterectomy
SAN DIEGO – The demand for gynecologic oncologists to perform robotic hysterectomies – even for benign indications – has increased to the point that additional fellowship training spots will be... (Source: Ob.Gyn. News)
Source: Ob.Gyn. News - June 8, 2016 Category: OBGYN Source Type: research