Selective release of gastrointestinal hormones induced by an orally active GPR39 agonist
Publication date: Available online 9 March 2021Source: Molecular MetabolismAuthor(s): Kaare V. Grunddal, Thi A. Diep, Natalia Petersen, Iain R. Tough, Louise J. Skov, Lingzhi Liu, Jesse A. Buijink, Franziska Mende, Chunyu Jin, Sara L. Jepsen, Louis M.E. Sørensen, Michael P. Achiam, Rune B. Strandby, Anders Bach, Bolette Hartmann, Thomas M. Frimurer, Siv A. Hjorth, Michel Bouvier, Helen Cox, Birgitte Holst (Source: Molecular Metabolism)
Source: Molecular Metabolism - March 10, 2021 Category: Endocrinology Source Type: research

Advances in the Treatment of Metabolic Diseases
Publication date: Available online 9 March 2021Source: Molecular MetabolismAuthor(s): Richard D. DiMarchi (Source: Molecular Metabolism)
Source: Molecular Metabolism - March 10, 2021 Category: Endocrinology Source Type: research

RNA m6A reader IMP2/IGF2BP2 promotes pancreatic β-cell proliferation and insulin secretion by enhancing PDX1 expression
Publication date: Available online 9 March 2021Source: Molecular MetabolismAuthor(s): Laura Regué, Liping Zhao, Fei Ji, Hua Wang, Joe Avruch, Ning Dai (Source: Molecular Metabolism)
Source: Molecular Metabolism - March 9, 2021 Category: Endocrinology Source Type: research

The melanocortin pathway and energy homeostasis: From discovery to obesity therapy
Publication date: Available online 6 March 2021Source: Molecular MetabolismAuthor(s): Giles S.H. Yeo, Daniela Herrera Moro Chao, Anna-Maria Siegert, Zoe M. Koerperich, Mark D. Ericson, Stephanie E. Simonds, Courtney M. Larson, Serge Luquet, Iain Clarke, Shubh Sharma, Karine Clément, Michael A. Cowley, Carrie Haskell-Luevano, Lex Van Der Ploeg, Roger A.H. Adan (Source: Molecular Metabolism)
Source: Molecular Metabolism - March 6, 2021 Category: Endocrinology Source Type: research

Osteocalcin and vascular function, is there a cross-talk?
Publication date: Available online 6 March 2021Source: Molecular MetabolismAuthor(s): Alexander Tacey, Alan Hayes, Anthony Zulli, Itamar Levinger (Source: Molecular Metabolism)
Source: Molecular Metabolism - March 6, 2021 Category: Endocrinology Source Type: research

Brown adipocyte-specific knockout of Bmal1 causes mild but significant impairment of thermogenesis in mice
Publication date: Available online 3 March 2021Source: Molecular MetabolismAuthor(s): Nazmul Hasan, Naoto Nagata, Jun-ichi Morishige, Md Tarikul Islam, Zheng Jing, Ken-ichi Harada, Mieda Michihiro, Masanori Ono, Hiroshi Fujiwara, Takiko Daikoku, Tomoko Fujiwara, Yoshiko Maida, Tsuguhito Ota, Shigeki Shimba, Shuichi Kaneko, Akio Fujimura, Hitoshi Ando (Source: Molecular Metabolism)
Source: Molecular Metabolism - March 5, 2021 Category: Endocrinology Source Type: research

Loss of mitochondrial aconitase promotes colorectal cancer progression via SCD1-mediated lipid remodeling
Publication date: Available online 3 March 2021Source: Molecular MetabolismAuthor(s): Xin You, Jingyu Tian, Hui Zhang, Yunhua Guo, Jing Yang, Chaofeng Zhu, Ming Song, Peng Wang, Zexian Liu, John Cancilla, Wenhua Lu, Christhophe Glorieux, Shijun Wen, Hongli Du, Peng Huang, Yumin Hu (Source: Molecular Metabolism)
Source: Molecular Metabolism - March 5, 2021 Category: Endocrinology Source Type: research

Multiple antisense oligonucleotides targeted against monoacylglycerol acyltransferase 1 (Mogat1) improve glucose metabolism independently of Mogat1
Publication date: Available online 3 March 2021Source: Molecular MetabolismAuthor(s): Andrew J. Lutkewitte, Jason M. Singer, Trevor M. Shew, Michael R. Martino, Angela M. Hall, Mai He, Brian N. Finck (Source: Molecular Metabolism)
Source: Molecular Metabolism - March 3, 2021 Category: Endocrinology Source Type: research

Pharmacologic inhibition of Ketohexokinase prevents fructose-induced metabolic dysfunction
Publication date: Available online 3 March 2021Source: Molecular MetabolismAuthor(s): Jemy A. Gutierrez, Wei Liu, Sylvie Perez, Gang Xing, Gabriele Sonnenberg, Kou Kou, Matt Blatnik, Richard Allen, Yan Weng, Nicholas B. Vera, Kristin Chidsey, Arthur Bergman, Veena Somayaji, Collin Crowley, Michelle F. Clasquin, Anu Nigam, Melissa A. Fulham, Derek M. Erion, Trenton T. Ross, William P. Esler (Source: Molecular Metabolism)
Source: Molecular Metabolism - March 3, 2021 Category: Endocrinology Source Type: research

Spatiotemporal GLP-1 and GIP receptor signaling and trafficking/recycling dynamics induced by selected receptor mono- and dual-agonists
Publication date: July 2021Source: Molecular Metabolism, Volume 49Author(s): Aaron Novikoff, Shannon L. O'Brien, Miriam Bernecker, Gerald Grandl, Maximilian Kleinert, Patrick J. Knerr, Kerstin Stemmer, Martin Klingenspor, Anja Zeigerer, Richard DiMarchi, Matthias H. Tschöp, Brian Finan, Davide Calebiro, Timo D. Müller (Source: Molecular Metabolism)
Source: Molecular Metabolism - February 28, 2021 Category: Endocrinology Source Type: research

Adipocyte Integrin-Linked Kinase Plays a Key Role in the Development of Diet-Induced Adipose Insulin Resistance in Male Mice
Publication date: Available online 26 February 2021Source: Molecular MetabolismAuthor(s): Aimée R. Bugler-Lamb, Annie Hasib, Xiong Weng, Chandani K. Hennayake, Chenshi Lin, Rory J. McCrimmon, Roland H. Stimson, Michael L.J. Ashford, David H. Wasserman, Li Kang (Source: Molecular Metabolism)
Source: Molecular Metabolism - February 27, 2021 Category: Endocrinology Source Type: research

Notum Deacylates Octanoylated Ghrelin
Publication date: Available online 27 February 2021Source: Molecular MetabolismAuthor(s): Yuguang Zhao, Laura-Nadine Schuhmacher, Morgan Roberts, Satoshi Kakugawa, Ganka Bineva-Todd, Steve Howell, Nicola O'Reilly, Christine Perret, Ambrosius P. Snijders, Jean-Paul Vincent, E. Yvonne Jones (Source: Molecular Metabolism)
Source: Molecular Metabolism - February 27, 2021 Category: Endocrinology Source Type: research

Insulin: A Pacesetter for the Shape of Modern Biomedical Science and the Nobel Prize
Publication date: Available online 18 February 2021Source: Molecular MetabolismAuthor(s): Jeffrey S. Flier, C. Ronald Kahn (Source: Molecular Metabolism)
Source: Molecular Metabolism - February 20, 2021 Category: Endocrinology Source Type: research

Genetic activation of α-cell glucokinase in mice causes enhanced glucose-suppression of glucagon secretion during normal and diabetic states
Publication date: Available online 19 February 2021Source: Molecular MetabolismAuthor(s): Varun Bahl, Catherine Lee May, Alanis Perez, Benjamin Glaser, Klaus H. Kaestner (Source: Molecular Metabolism)
Source: Molecular Metabolism - February 20, 2021 Category: Endocrinology Source Type: research

The gut–brain axis: Identifying new therapeutic approaches for type 2 diabetes, obesity, and related disorders
Publication date: Available online 3 February 2021Source: Molecular MetabolismAuthor(s): Paul Richards, Nancy A. Thornberry, Shirly Pinto (Source: Molecular Metabolism)
Source: Molecular Metabolism - February 18, 2021 Category: Endocrinology Source Type: research