Amiodarone does not affect brain injury in a rat model of transient forebrain ischemia
ConclusionsThe administration of amiodarone immediately after transient forebrain ischemia did not worsen spatial cognitive function or neuronal survival in the hippocampal CA1 region in rats. The current results must be applied with caution in humans. However, they indicate that the potential neurotoxicity induced by amiodarone during resuscitation after cardiac arrest may be negligible.ResumenObjetivosLa amiodarona puede causar neurotoxicidad que afecte a los desenlaces de los pacientes si se usa durante la reanimación cardiopulmonar (RCP), si bien este fármaco se ha prescrito habitualmente a pacientes durante la RCP. ...
Source: Medicina Intensiva - October 26, 2019 Category: Intensive Care Source Type: research

Is mortality in elderly septic patients as high as expected? Long-term mortality in a surgical sample cohort
ConclusionsThe results indicate that there is no significant difference in mortality among the different age groups. About 50% of the elderly patients survive a septic process. There is a close relationship between the number of affected organs and days of dysfunction, the use of interventional techniques and long-term mortality.ResumenObjetivoDeterminar las diferencias en la mortalidad a corto y largo plazo en pacientes sèc)pticos ancianos con síndrome de disfunción multiorgánica, y cuáles son los factores de riesgo determinantes de esta.Materiales y mèc)todosEstudio retrospectivo de cohortes de 206 pacientes mayore...
Source: Medicina Intensiva - October 26, 2019 Category: Intensive Care Source Type: research

Safety of aerosol therapy in children during noninvasive ventilation with helmet and total face mask
ConclusionsThe probability of suffering an adverse effect related to nebulization is extremely low when using a helmet or TFM. Inhaled therapy with TFM may shorten PICU stay in some patients.ResumenObjetivoEvaluar las consecuencias de la medicación nebulizada en pacientes con ventilación no invasiva (VNI) con mascarilla facial total (MFT) y casco.DiseñoEstudio analítico descriptivo sobre una cohorte prospectiva de pacientes.ÁmbitoUCIP de hospital de tercer nivel.PacientesTodos los pacientes ingresados en UCIP (muestreo consecutivo) con VNI con casco o MFT durante 29 meses. No se excluyeron pacientes.IntervencionesSe a...
Source: Medicina Intensiva - October 26, 2019 Category: Intensive Care Source Type: research

Severity scores should incorporate limitations on life support for predicting mortality
Publication date: November 2019Source: Medicina Intensiva (English Edition), Volume 43, Issue 8Author(s): Rafael Fernandez, Lara Ventura, Caroline Macharete, Ignacio Catalan, Silvia Cano, Josep-Maria Alcoverro, Carles Subira, Jaume Masclans, Gina Rognoni, Olga Rubio (Source: Medicina Intensiva)
Source: Medicina Intensiva - October 26, 2019 Category: Intensive Care Source Type: research

Lymphopenic hospital acquired sepsis (L-HAS): An immunological phenotype conferring higher risk of mortality
Publication date: November 2019Source: Medicina Intensiva (English Edition), Volume 43, Issue 8Author(s): C. López-Mestanza, D. Andaluz-Ojeda, J.R. Gómez-López, J.F. Bermejo-Martín (Source: Medicina Intensiva)
Source: Medicina Intensiva - October 26, 2019 Category: Intensive Care Source Type: research

Cytokine release syndrome. Reviewing a new entity in the intensive care unit
Publication date: November 2019Source: Medicina Intensiva (English Edition), Volume 43, Issue 8Author(s): Alejandra García Roche, Cándido Díaz Lagares, Elena Élez, Ricard Ferrer RocaAbstractImmunotherapy seeks to harness the power of the immune system to eradicate malignant tissues. Despite impressive therapeutic success, however, it can be accompanied by severe adverse effects such as cytokine release syndrome (CRS). These therapies cause the release of a great amount of cytokines, with IL-6 playing a central role, that can potentially lead to multiple organ dysfunction. The diagnosis is based on the presence of compa...
Source: Medicina Intensiva - October 26, 2019 Category: Intensive Care Source Type: research

Evaluation of a dental brushing protocol with aspiration in patients hospitalized in an intensive care unit using image and microbiological analyzes: Pilot study: Evaluación de un protocolo de cepillado dental con aspiración en pacientes hospitalizados en la unidad de cuidados intensivos utilizando análisis de imagen y microbiología: estudio piloto
Publication date: Available online 16 October 2019Source: Medicina Intensiva (English Edition)Author(s): T.B. Santos Zambrano, A.C. Poletto, B. Gonçalves Dias, R. Guayato Nomura, W. Junior Trevisan, R.S. Couto de Almeida (Source: Medicina Intensiva)
Source: Medicina Intensiva - October 16, 2019 Category: Intensive Care Source Type: research

Postoperative management in the Intensive Care Unit of head and neck surgery patients
Publication date: Available online 15 October 2019Source: Medicina Intensiva (English Edition)Author(s): L. Alcázar Sánchez-Elvira, S. Bacian Martínez, L. del Toro Gil, V. Gómez TelloAbstractPatient care after major head and neck surgery has changed in recent years. Tumors are the most common reasons for this type of surgery, though it is also used to treat benign conditions.Recent advances in equipment and surgical techniques have improved the postoperative course in this field, allowing early recovery, less pain and infection, a shorter hospital stay, and even better aesthetic results. This is due to the use of minim...
Source: Medicina Intensiva - October 15, 2019 Category: Intensive Care Source Type: research

Can we justify the use of physical and mechanical restraint in pediatric patients admitted to the Intensive Care Unit?: [[es]]¿Está justificado el uso de contenciones físicas y mecánicas en el paciente pediátrico ingresado en una unidad de cuidados intensivos?
Publication date: Available online 12 October 2019Source: Medicina Intensiva (English Edition)Author(s): A. Bosch-Alcaraz, G. Via-Clavero (Source: Medicina Intensiva)
Source: Medicina Intensiva - October 12, 2019 Category: Intensive Care Source Type: research

Human T lymphotropic virus (HTLV I and II) antibodies seroprevalence among organ donors
Publication date: Available online 12 October 2019Source: Medicina Intensiva (English Edition)Author(s): O. Leizaola Irigoyen, B. Leoz Gordillo, S. Balboa Palomino, M. Rodríguez Perez, B. Mahillo Durán, D. Escudero Augusto (Source: Medicina Intensiva)
Source: Medicina Intensiva - October 12, 2019 Category: Intensive Care Source Type: research

Risk and protective factors of secondary traumatic stress in Intensive Care Units: An exploratory study in a hospital in Madrid (Spain)
ConclusionsThis predictive model of STS identifies protective factors which could be reinforced, such as harmonious passion, and risk factors which should be reduced, such as empathy and emotional effort, with a view to promoting quality of care and quality of life among these professionals.ResumenObjetivoProponer un modelo de predictores del estrés traumático secundario (ETS).DiseñoSe trata de un diseño transversal descriptivo.ÁmbitoEl estudio se llevó a cabo en las unidades de cuidados intensivos de un hospital terciario de Madrid.ParticipantesLa muestra estuvo formada por 103 profesionales sanitarios.Intervencione...
Source: Medicina Intensiva - October 12, 2019 Category: Intensive Care Source Type: research

The professional use of Twitter to create a global pediatric intensive care community
Publication date: Available online 9 October 2019Source: Medicina Intensiva (English Edition)Author(s): S. González-Dambrauskas, M. Rodríguez-Rubio (Source: Medicina Intensiva)
Source: Medicina Intensiva - October 10, 2019 Category: Intensive Care Source Type: research

Coronary aneurysm with calcification in a young adult: An unusual cause of cardiac arrest
Publication date: October 2019Source: Medicina Intensiva (English Edition), Volume 43, Issue 7Author(s): J. Song, S.J. Gong, Y.H. Yu (Source: Medicina Intensiva)
Source: Medicina Intensiva - October 4, 2019 Category: Intensive Care Source Type: research

Prone positioning before extracorporeal membrane oxygenation for severe acute respiratory distress syndrome: A retrospective multicenter study
ConclusionsProne positioning before ECMO was not associated to increased mortality and tended to exert a protective effect.ResumenObjetivoEvaluar los resultados clínicos de pacientes con síndrome de dificultad respiratoria aguda (SDRA) quienes fueron colocados en decúbito prono previo a la oxigenación con membrana extracorpórea (ECMO).DiseñoAnálisis retrospectivo de una cohorte multicéntrico.EscenarioPacientes admitidos en las unidades de cuidado intensivo de 11 hospitales en Corea.PacientesLos pacientes fueron divididos en aquellos que fueron colocados en decúbito prono antes de la ECMO (n = 28) y aquel...
Source: Medicina Intensiva - October 4, 2019 Category: Intensive Care Source Type: research

Renal replacement therapy in severe phenobarbital poisoning: Another brick in the wall
Publication date: October 2019Source: Medicina Intensiva (English Edition), Volume 43, Issue 7Author(s): A. Bedet, A. Alestra, D. Vodovar, A. Mekontso Dessap, N. de Prost (Source: Medicina Intensiva)
Source: Medicina Intensiva - October 4, 2019 Category: Intensive Care Source Type: research