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Antiviral effects of Lactobacillus crispatus against HSV-2 in mammalian cell lines
Conclusion L. crispatus appears to inhibit the entry of the virus into cells by trapping HSV-2 particles. In addition, formation of L. crispatus microcolonies in the cell surface could block HSV-2 receptors and prevent viral entry to cells in initial infection steps. (Source: Journal of the Chinese Medical Association)
Source: Journal of the Chinese Medical Association - November 18, 2017 Category: General Medicine Source Type: research

Bacterial biofilm and associated infections
Publication date: Available online 15 October 2017 Source:Journal of the Chinese Medical Association Author(s): Muhsin Jamal, Wisal Ahmad, Saadia Andleeb, Fazal Jalil, Muhammad Imran, Muhammad Asif Nawaz, Tahir Hussain, Muhammad Ali, Muhammad Rafiq, Muhammad Atif Kamil Microscopic entities, microorganisms that drastically affect human health need to be thoroughly investigated. A biofilm is an architectural colony of microorganisms, within a matrix of extracellular polymeric substance that they produce. Biofilm contains microbial cells adherent to one-another and to a static surface (living or non-living). Bact...
Source: Journal of the Chinese Medical Association - November 18, 2017 Category: General Medicine Source Type: research

Surgical treatment of active native mitral infective endocarditis: A  meta-analysis of current evidence
Conclusions This meta-analysis suggests that MVP may be associated with superior postoperative survival outcomes compared with MVR. MVP is desirable, if possible, as a durable alternative to replacement. However, we must consider the influence of different patient characteristics and surgeons' preferences on the choice of surgical approach, and additional powered clinical trials will be required to confirm these findings. (Source: Journal of the Chinese Medical Association)
Source: Journal of the Chinese Medical Association - November 18, 2017 Category: General Medicine Source Type: research

The impact of open to collaborative care model in cardiovascular surgical  unit
This study was a retrospective, observational study conducted in the cardiovascular care unit of a teaching hospital. All patients who were above 20 years old and had received cardiovascular operation were enrolled for data collection and analysis. Results A total of 270 subjects were enrolled for analysis during the 2-year study period. In the collaborative care model, the CVSU length of stay (p = 0.001) and CVSU-free days (p = 0.0008) were significantly better than those in an open care model. Discussion The collaborative care model improved postoperative outcome in the cardiovascular surgical unit for those needin...
Source: Journal of the Chinese Medical Association - November 18, 2017 Category: General Medicine Source Type: research

SIRT1 acts as a potential tumor suppressor in oral squamous cell carcinoma
Conclusion The present results suggest that SIRT1 is a potential tumor suppressor in OSCC. (Source: Journal of the Chinese Medical Association)
Source: Journal of the Chinese Medical Association - November 18, 2017 Category: General Medicine Source Type: research

Aster yomena extract ameliorates pro-inflammatory immune response by suppressing NF- κB activation in RAW 264.7 cells
Conclusion These results suggest that A. yomena may have anti-inflammatory activity in vitro, suggesting this herb could be a source of natural anti-inflammatory agents. (Source: Journal of the Chinese Medical Association)
Source: Journal of the Chinese Medical Association - November 18, 2017 Category: General Medicine Source Type: research

Angiographic assessment of atherosclerotic load at the lower extremity in patients with diabetic foot and charcot neuro-arthropathy
Conclusion This angiographic study confirms that the atherosclerotic load in patients with diabetic foot and chronic charcot neuro-arthropathy is significantly less than in patients with neuroischemic diabetic foot wounds without chronic charcot neuro-arthropathy. (Source: Journal of the Chinese Medical Association)
Source: Journal of the Chinese Medical Association - November 18, 2017 Category: General Medicine Source Type: research

The impact of pathological complete response after neoadjuvant chemoradiotherapy in locally advanced squamous cell carcinoma of esophagus
Conclusion Pathological complete response after neoadjuvant chemoradiotherapy is associated with a significant survival benefit in patients with locally advanced squamous cell carcinoma of esophagus. The toxicities related to neoadjuvant chemoradiotherapy were tolerable. (Source: Journal of the Chinese Medical Association)
Source: Journal of the Chinese Medical Association - November 18, 2017 Category: General Medicine Source Type: research

Intraprocedural arterial perforation during neuroendovascular therapy: Preliminary result of a dual-trained endovascular neurosurgeon in the neurosurgical hybrid operating room
Conclusion IPAP can be rescued successfully with an aggressive approach and quick conversion to backup surgery by a dual-trained endovascular neurosurgeon in the hybrid OR. The value of the hybrid OR in neuroendovascular therapy should be further investigated in the future. (Source: Journal of the Chinese Medical Association)
Source: Journal of the Chinese Medical Association - November 18, 2017 Category: General Medicine Source Type: research

Influence of visual impairment and hearing impairment on functional dependence status among people in Taiwan —An evaluation using the WHODAS 2.0 score
Conclusion WHODAS 2.0 scores are strongly correlated with the severity of VI. Mild VI should be targeted for treatment and referral as early as possible. Compared with the patients with HI, the patients with VI more frequently experience barriers to accessing environmental factors. (Source: Journal of the Chinese Medical Association)
Source: Journal of the Chinese Medical Association - November 18, 2017 Category: General Medicine Source Type: research

The value of medical student radiology education: A comparison of 1-week, 2-week, electives, and compulsories
Conclusion Adding a 1-week dedicated radiology rotation to fifth- or sixth-year students after they finished the standard radiology course is beneficial to students. This type of vertical radiology curriculum is valuable and should be incorporated into formal medical school curricula. (Source: Journal of the Chinese Medical Association)
Source: Journal of the Chinese Medical Association - November 18, 2017 Category: General Medicine Source Type: research

Laparoscopic versus open hepatectomy approach for regional hepatolithiasis: A meta-analysis
Conclusion LH for regional hepatolithiasis appears to be a promising treatment modality for patients with intrahepatic stones. However, large numbers of patients and prospective, randomized, controlled studies are required to lead to a more comprehensive comparison of the two procedures. (Source: Journal of the Chinese Medical Association)
Source: Journal of the Chinese Medical Association - November 18, 2017 Category: General Medicine Source Type: research

Distinguishing non-obstructive azoospermia from obstructive azoospermia in Taiwanese patients by hormone profile and testis size
Conclusion A combination of FSH >9.2 mIU/ml and right testis size <15 ml was a strong predictor of NOA in our Taiwanese patients. (Source: Journal of the Chinese Medical Association)
Source: Journal of the Chinese Medical Association - November 18, 2017 Category: General Medicine Source Type: research

Anti-atherosclerotic effect of Fermentum Rubrum and Gynostemma pentaphyllum mixture in high-fat emulsion- and vitamin D3-induced atherosclerotic rats
Conclusion the anti-atherosclerotic effects of HG were superior to those of simvastatin, Hongqu, and the gypenosides. Therefore, HG may be a useful anti-atherosclerotic TCM preparation. (Source: Journal of the Chinese Medical Association)
Source: Journal of the Chinese Medical Association - November 18, 2017 Category: General Medicine Source Type: research

A frequently asked question: Is it normal not to feel my baby's movements yet?
Conclusion This study revealed factors that affect maternal perception of first fetal movements in both a positive and negative manner. Although it is hard to define an exact time for each individual, an approximate time according to our data can be given to a mother, which considers an affecting factor on the basis of average gestational week. (Source: Journal of the Chinese Medical Association)
Source: Journal of the Chinese Medical Association - November 18, 2017 Category: General Medicine Source Type: research