Ki67, CD105, and α‐SMA expressions better relate the binary oral epithelial dysplasia grading system of World Health Organization
ConclusionThe expressions of ki67, CD105, and α‐SMA markers compliment binary grading system of OED in OPMDS, thus justifying its use in clinical practice. (Source: Journal of Oral Pathology and Medicine)
Source: Journal of Oral Pathology and Medicine - July 25, 2017 Category: Pathology Authors: Amol Ramchandra Gadbail, Minal S. Chaudhary, Sachin C. Sarode, Madhuri Gawande, Sheetal Korde, Satyajit Ashok Tekade, Shailesh Gondivkar, Alka Hande, Rupesh Maladhari Tags: ORIGINAL ARTICLE Source Type: research

Circulating high mobility group AT ‐hook 2 and pleomorphic adenoma gene 1 in blood of patients with oral squamous cell carcinoma
ConclusionCirculating HMGA2 levels are increased in OSCC patients and may potentially serve as a significant index to evaluate OSCC diagnosis. (Source: Journal of Oral Pathology and Medicine)
Source: Journal of Oral Pathology and Medicine - July 24, 2017 Category: Pathology Authors: Wenhao Ren, Ling Gao, Fan Li, Cui Qiang, Shaoming Li, Jingjing Zheng, Xinjuan Kong, Jing Deng, Guangfeng Cai, Hao Zhang, Minzhan Zhou, Keqian Zhi Tags: ORIGINAL ARTICLE Source Type: research

Uncovering the role of brain ‐derived neurotrophic factor/tyrosine kinase receptor B signaling in head and neck malignancies
Brain‐derived neurotrophic factor (BDNF) is a member of the neurotrophin family of growth factors that was first known as responsible for sustain the growth, function, and plasticity of neural cells. BDNF exerts its effects by binding to the tyrosine kinase receptor B (TrkB). The BDNF/TrkB axis has been reported to be overexpressed in several neurogenic and non‐neurogenic tumors. Its higher expression was associated with a poor prognosis to patients affected by different human malignancies, tumor growth, invasion, and metastasis; epithelial‐mesenchymal transition and resistance to chemotherapy. BDNF/TrkB represent pr...
Source: Journal of Oral Pathology and Medicine - July 22, 2017 Category: Pathology Authors: Juliana Kern Moraes, Vivian Petersen Wagner, Felipe Paiva Fonseca, Pablo Agustin Vargas, Caroline Brunetto Farias, Rafael Roesler, Manoela Domingues Martins Tags: REVIEW ARTICLE Source Type: research

An in  vitro study of the long non‐coding RNA TUG1 in tongue squamous cell carcinoma
ConclusionThe lncRNA TUG1 may represent a potential oncogene in TSCC. (Source: Journal of Oral Pathology and Medicine)
Source: Journal of Oral Pathology and Medicine - July 16, 2017 Category: Pathology Authors: Zhi ‐qiang Li, Rui Zou, Ke‐Xiong Ouyang, Wei‐Jian Ai Tags: ORIGINAL ARTICLE Source Type: research

Peritumoral cuffing by T ‐cell tumor‐infiltrating lymphocytes distinguishes HPV‐related oropharyngeal squamous cell carcinoma from oral cavity squamous cell carcinoma
ConclusionsFor the first time, we show an architectural pattern of immune infiltrate in HNSCC is seen exclusively in HPV‐positive patients with improved recurrence‐free survival and suggests an organized host immunological response contributes to disease control. (Source: Journal of Oral Pathology and Medicine)
Source: Journal of Oral Pathology and Medicine - July 14, 2017 Category: Pathology Authors: Kate Poropatich, David Hernandez, Joel Fontanarosa, Koshonna Brown, Gayle Woloschak, Ajit Paintal, Kirtee Raparia, Sandeep Samant Tags: ORIGINAL ARTICLE Source Type: research