Quercus Brantii Lindl. Vaginal Cream versus Placebo on Bacterial Vaginosis: a Randomized Clinical Trial
Publication date: Available online 20 November 2018Source: Journal of Herbal MedicineAuthor(s): Atefeh Zare, Zeinab Moshfeghy, Mohammad M. Zarshenas, Bahia Namavar jahromi, Marzieh Akbarzadeh, Mehrab SayadiAbstractThe current study aimed to compare the effects of Quercus brantii Lindl. vaginal cream in combination with metronidazole tablet on Bacterial Vaginosis (BV). A total of 176 eligible women with BV were enrolled. Diagnosis was based on having 3 or more signs described by Amsel’s criteria and a Nugent score of ≥7. Symptoms were evaluated before and after treatments. Participants were divided into two experimental...
Source: Journal of Herbal Medicine - November 21, 2018 Category: Complementary Medicine Source Type: research
Inhibition of Key Enzymes Linked to Diabetes by Annona senegalensis Pers (Annonaceae) Leaf In vitro
This study was aimed at investigating the inhibitory potential of A. senegalensis leaf extracts and fractions on the activities of some enzymes (α-amylase and α-glucosidase) linked to diabetes. Plant samples were extracted with n-hexane (HEX), ethyl cetate (EtOAc) and ethanol (EtOH) and the extracts were subjected to in vitro antidiabetic studies. The most active extract was further fractionated using column chromatography and the fractions obtained were screened for the inhibitory activities whilst the possible bioactive compounds were determined by Gas Chromatography Mass Spectroscopy (GC-MS). From the results, ethanol...
Source: Journal of Herbal Medicine - November 21, 2018 Category: Complementary Medicine Source Type: research
Nigella sativa improves anemia, enhances immunity and relieves iron overload-induced oxidative stress as a novel promising treatment in children having beta-thalassemia major
ConclusionNS decreased iron overload-induced oxidative stress and hemolytic anemia. NS is a promising treatment for thalassemia to potentiate therapeutic effects and alleviate side effects of iron chelation therapy. Limitations to this study included the small number of patients and the relatively short post treatment follow-up time. Future research regarding the use of NS for the treatment of thalassemia is highly recommendedThis clinical trial was registered in: ClinicalTrials.gov. Trial ID: NCT02816957 (Source: Journal of Herbal Medicine)
Source: Journal of Herbal Medicine - November 18, 2018 Category: Complementary Medicine Source Type: research
Effect of Rosa canina L. (Rose-hip) on cold during winter season in a middle-class population: A randomized, double-blinded, placebo-controlled trial
ConclusionOur data suggest that administration of liquid Rose-hip reduces the incidence of colds by 18% and lowers the number of patients reporting the different symptoms of cold. (Source: Journal of Herbal Medicine)
Source: Journal of Herbal Medicine - November 12, 2018 Category: Complementary Medicine Source Type: research
HPLC/LC-MS Guided Phytochemical and In vitro Screening of Astragalus membranaceus (Fabaceae), and Prediction of Possible Interactions with CYP2B6
In conclusion, the root extracts of A.membranaceus have been shown to inhibit CYP2B6, with IC50 values below the estimated hepatic circulation concentrations. This herb therefore may cause adverse drug interactions with CYPs, when co-administered with medications metabolized by CYP2B6.Graphical abstract (Source: Journal of Herbal Medicine)
Source: Journal of Herbal Medicine - November 3, 2018 Category: Complementary Medicine Source Type: research
Ferula species: A rich source of antimicrobial compounds
Publication date: Available online 1 November 2018Source: Journal of Herbal MedicineAuthor(s): Zahra Boghrati, Mehrdad IranshahiAbstractFerula species, particularly F. assa-foetida and F. gummosa, have a long history of use in traditional medicine. They have extensively been used for the treatment of infectious diseases including diarrhea, skin infection, intestinal parasites and influenza.This review is an attempt to explore secondary metabolites from Ferula species as a rich source of molecules with antimicrobial property and highlights the gaps in our knowledge deserving future research. In this review, the authors expl...
Source: Journal of Herbal Medicine - November 2, 2018 Category: Complementary Medicine Source Type: research
Health-promoting properties of Corchorus leaves: A review
Publication date: Available online 29 October 2018Source: Journal of Herbal MedicineAuthor(s): Neetu Kumari, Shashi Bhushan Choudhary, Hariom Kumar Sharma, Binay Kumar Singh, Arroju Anil KumarAbstractThe genus Corchorus is commercially known for its phloem fibre. Moreover, the tender leaves of Corchorus have also long been recognized by Asian and African folk medicine practitioners to manage pain, fever, dysentery, sexual disorders and degenerative diseases. Given the significant medicinal properties attributed to the genus, the authors performed a thorough literature review to investigate the biological roles and toxicolo...
Source: Journal of Herbal Medicine - October 30, 2018 Category: Complementary Medicine Source Type: research
The effect of a mixture of Nigella sativa and Thymus vulgaris extracts in children with refractory epilepsies; A randomized trial
Publication date: Available online 27 October 2018Source: Journal of Herbal MedicineAuthor(s): Ali Akbar Momen, Ali Asghar Hemati, Gholamreza Hoshmand, Maryam Heydar Azadzadeh, Reza Azizi MalamiriAbstractMore than 25% of seizures in children are refractory to anti-seizure medications and need other modalities to control. Recently, herbal agents with anticonvulsive effects on seizure models in animals have received significant attention, but studies that show their impact on seizures in children are scarce. In a randomized, double-blind placebo-controlled cross-over design, we tried to demonstrate the efficacy of a mixture ...
Source: Journal of Herbal Medicine - October 27, 2018 Category: Complementary Medicine Source Type: research
Mechanisms of Action of Ginger in Nuclear Factor-kappaB Signaling Pathways in Diabetes
Publication date: Available online 21 October 2018Source: Journal of Herbal MedicineAuthor(s): Ahmad Saedisomeolia, Motahereh Makhdoomi Arzati, Mina Abdolahi, Mohsen Sedighiyan, Alejandra Rangel, Gerald Muench, Meysam Zarezadeh, Arash Jafarieh, Niyaz Mohammadzadeh HonarvarAbstractDiabetes mellitus is considered a metabolic disorder characterized by high blood sugar. Active disease is associated with low grade chronic inflammation resulting from the enhanced release of inflammatory mediators such as interleukin (IL)-1 β, IL-6, induced nitric oxide synthase, and cyclooxygenase-2 enzymes that lead to insulin resistance and d...
Source: Journal of Herbal Medicine - October 21, 2018 Category: Complementary Medicine Source Type: research
An evaluation of garlic products available in Australian pharmacies–From the label to the laboratory
Publication date: Available online 21 September 2018Source: Journal of Herbal MedicineAuthor(s): Wai-Jo Jocelin Chan, Andrew J. McLachlan, Nial J. Wheate, Joanna E. HarnettAbstractGarlic is one of the most commonly used herbal medicines worldwide. There is medium quality evidence to support that specific garlic formulations at specific doses have an antihypertensive effect in a cohort of individuals with hypertension. There is lower quality evidence for garlic’s hypolipidaemic effects. While there are many garlic products available in Australian pharmacies, it is unclear if these products are formulated based on the curr...
Source: Journal of Herbal Medicine - October 16, 2018 Category: Complementary Medicine Source Type: research
Evaluation of the anti-stress effects of five Tunisian aromatic and medicinal plants in vitro
Publication date: Available online 12 October 2018Source: Journal of Herbal MedicineAuthor(s): Mahmoud Ben Othman, Mohamed Neffati, Hiroko IsodaAbstractThe present study was designed to evaluate the anti-stress effects of the ethanol extracts of five medicinal plants from Southern part of Tunisia, traditionally used in folk medicine: Cymbopogon schoenanthus Spreng. (CSEE), Crithmum maritimum L. (CMEE), Arthrophytum scoparium (Pomel) ll’jin (ASEE), Artemisia herba-alba Asso. (AHEE), and Rhanterium suaveolens Desf. (RSEE). Assays using SH-SY5Y cells and HSP47-transformed CHO cells (HSP47+/- cells) were performed. Heat (at ...
Source: Journal of Herbal Medicine - October 13, 2018 Category: Complementary Medicine Source Type: research
Phytochemical characteristics and potential therapeutic properties of blue honeysuckle Lonicera caerulea L. (Caprifoliaceae)
Publication date: Available online 10 October 2018Source: Journal of Herbal MedicineAuthor(s): Rafał Becker, Anna SzakielAbstractLonicera caerulea, known as honeyberry, blue honeysuckle, sweet berry honeysuckle, edible honeysuckle, or haskap, is a perennial fruit-bearing plant belonging to the family Caprifoliaceae. Currently, the cultivation of this plant species is becoming increasingly popular due to the early ripening of the fruits, the plant´s exceptional resistance to frost, pests, and diseases, as well as for its potential health-promoting and therapeutic properties. Phytochemical analysis of blue honeysuckle cons...
Source: Journal of Herbal Medicine - October 12, 2018 Category: Complementary Medicine Source Type: research
Case report on recovery from Japanese encephalitis virus infection by complementary use of phytolacca-mother tincture and in silico analysis
Publication date: Available online 6 October 2018Source: Journal of Herbal MedicineAuthor(s): Harish Chandra Chaudhury, Akhil Kumar Panda, Sarat Kumar Behera, Manjushree Mohanty, Bharat Bhusan SubudhiAbstractPhytolacca Americana Lor pokeweed has medicinal application against inflammation, arthritis, and viral fever infections in traditional medicines. Its mother tincture in the homeopathic system of medicine is used for many of these disease conditions. This is the first case study reporting the beneficial effects of Phytolacca-mother tincture against Japanese Encephalitis Virus (JEV) infection in an intensive care unit (I...
Source: Journal of Herbal Medicine - October 8, 2018 Category: Complementary Medicine Source Type: research
A clinical review of the effectiveness of tomato (Solanum lycopersicum) against cardiovascular dysfunction and related metabolic syndrome
In conclusion, consuming fresh tomato supplements may contribute to the prevention of obesity, diabetes and cardiovascular dysfunctions through positively affecting biochemical pathways associated with these conditions. (Source: Journal of Herbal Medicine)
Source: Journal of Herbal Medicine - October 5, 2018 Category: Complementary Medicine Source Type: research
Validation of Medicinal Herbs for Anti-tyrosinase Potential
Publication date: Available online 24 September 2018Source: Journal of Herbal MedicineAuthor(s): Pulok K. Mukherjee, Rajarshi Biswas, Akanksha Sharma, Subhodip Banerjee, Sayan Biswas, C.K. KatiyarAbstractTyrosinase is a key regulatory multifunctional enzyme containing copper that is responsible for the biosynthesis of melanin that determines the color of the skin. Accumulation of excessive melanin causes various dermatological disorders including melasma and age spots. Also, tyrosinase is responsible for enzymatic browning reactions in damaged fruits and vegetables. It deteriorates the color clarity of plant-derived food p...
Source: Journal of Herbal Medicine - October 4, 2018 Category: Complementary Medicine Source Type: research
