Protective role of hydroalcoholic extract of Cajanus cajan Linn leaves against memory impairment in sleep deprived experimental rats
ConclusionHECC possesses a protective effect against memory impairment indicating its therapeutic efficacy against memory loss as in Alzheimer's disease. Probable underlying mechanisms may be brain's AChE inhibition and increased antioxidant potential by HECC.Graphical abstract (Source: Journal of Ayurveda and Integrative Medicine)
Source: Journal of Ayurveda and Integrative Medicine - January 18, 2019 Category: Complementary Medicine Source Type: research

Ayurveda management of Guillain-Barre syndrome: A case report
Publication date: Available online 18 January 2019Source: Journal of Ayurveda and Integrative MedicineAuthor(s): Basavaraj R. Tubaki, Shruti TarapureAbstractGuillain-Barre syndrome (GBS) is a severe acute paralytic neuropathy with rapid progression usually occurring post infections. Inspite of the active medications it is associated with severe weakness, incomplete recovery and pain. Long disease course can cause autonomic dysfunction or deterioration in general health and life threatening complications like respiratory failures. Current case was diagnosed as GBS with motor, sensory & sphincter disturbance. Ayurveda diagno...
Source: Journal of Ayurveda and Integrative Medicine - January 18, 2019 Category: Complementary Medicine Source Type: research

Effect of a Multimodality ayurveda treatment in a case of Visphota kushta
Publication date: Available online 17 January 2019Source: Journal of Ayurveda and Integrative MedicineAuthor(s): I.V. Aiswarya, K. Parameswaran Namboothiri, P.V. AnandaramanAbstractVisphota kushta (blistering skin disease) is characterized by transparent blisters with thin skin covering. Management of Visphota Kushta in Ayurveda is rarely reported. The case reported here showed significant regression in the condition in short span of time and could completely stop the use of anti histamines and corticosteroids. A 32 year old female, presented with complaints of blisters over both upper and lower extremities associated with...
Source: Journal of Ayurveda and Integrative Medicine - January 17, 2019 Category: Complementary Medicine Source Type: research

Scientific validation of Anti-arthritic effect of Kashayams – a polyherbal formulation in collagen induced arthritic rats
ConclusionThis molecular mechanism of the investigation confirmed the clinical efficacy of Kashayams in preventing the progression of RA and gave an intuition of the scientific validation of Kashayams, an Ayurvedic classical medicine. (Source: Journal of Ayurveda and Integrative Medicine)
Source: Journal of Ayurveda and Integrative Medicine - January 17, 2019 Category: Complementary Medicine Source Type: research

A cross comparison between Ayurvedic etiology of Major Depressive Disorder and bidirectional effect of gut dysregulation
Publication date: Available online 15 January 2019Source: Journal of Ayurveda and Integrative MedicineAuthor(s): Eliot SteerAbstractAyurveda, an Indian medical science has been practiced for thousands of years. What makes Ayurveda relevant today is its subtle understanding of the environment and its focus on the generation of good health through one's own lifestyle choices. The digestive system has long been an area of critical importance within the Ayurvedic system and is only now being acknowledged by modern science as a key component in the regulation of physical and mental well-being. The gut microbiome and enteric ner...
Source: Journal of Ayurveda and Integrative Medicine - January 15, 2019 Category: Complementary Medicine Source Type: research

Modulation of proinflammatory cytokines and enzymes by polyherbal formulation Guggulutiktaka ghritam
ConclusionThe study revealed that GTG is a leukotriene and cytokine inhibitor. The inhibition in the production of cytokines may be due to the down-regulation of genes for TNF-α and IL-1β. The study provides a scientific validation on the possible anti-inflammatory mechanism of action of this traditionally used medicine. Identification of bioactive molecules would aid in developing newer therapeutics for control of chronic inflammation.Graphical abstract (Source: Journal of Ayurveda and Integrative Medicine)
Source: Journal of Ayurveda and Integrative Medicine - January 12, 2019 Category: Complementary Medicine Source Type: research

Shelf life evaluation of Laghu Sutashekhara Rasa – A preliminary assessment
ConclusionThe shelf life of LSR was found to be less than the given standards in official gazettes of Govt. of India. This decreased shelf life may be because of the predominantly (Approximately 70%) herbal component present in the formulation. (Source: Journal of Ayurveda and Integrative Medicine)
Source: Journal of Ayurveda and Integrative Medicine - January 11, 2019 Category: Complementary Medicine Source Type: research

RP-HPLC analysis of methanol extract of Viscum articulatum – A plant from Ayurveda
ConclusionThis RP-HPLC may be useful for quantitative estimation of the chemical constituents present in the plant extract as well as the quality assessment of the herbal product. (Source: Journal of Ayurveda and Integrative Medicine)
Source: Journal of Ayurveda and Integrative Medicine - January 11, 2019 Category: Complementary Medicine Source Type: research

Anticonvulsant effect of Sphaeranthus flower extracts in mice
In conclusion, the results of this study suggest that both the ME and AE possess promising anticonvulsant activity. It is further suggested that the flavonoids in the extract by the virtue of their effect on benzodiazepine site of GABA receptor, might be responsible for the effect, although no study is undertaken to prove this aspect. Nevertheless, the study provides pharmacological credibility to the anti-epileptic use of S. indicus suggested in Ayurveda. (Source: Journal of Ayurveda and Integrative Medicine)
Source: Journal of Ayurveda and Integrative Medicine - January 10, 2019 Category: Complementary Medicine Source Type: research

Unani concept of drug substitution (therapeutic interchange) and its validation on scientific parameters
ConclusionThe study, however, seemed to validate the concept on the basis of phytoconstituents, further pharmacological studies on the basis of properties and activities is required to strengthen the concept. (Source: Journal of Ayurveda and Integrative Medicine)
Source: Journal of Ayurveda and Integrative Medicine - January 10, 2019 Category: Complementary Medicine Source Type: research

Reinventing nano drug delivery systems for hydrophilic active ingredients in Ayurvedic lipid based formulations containing poly herbal decoction
ConclusionThe selected Ayurvedic formulation ‘anutailam’ found to contain novel nano drug delivery system to deliver water soluble ingredients across barriers. (Source: Journal of Ayurveda and Integrative Medicine)
Source: Journal of Ayurveda and Integrative Medicine - January 9, 2019 Category: Complementary Medicine Source Type: research

Effect of seeds of Entada phaseoloides on chronic restrain stress in mice
ConclusionMEEP altered endoplasmic reticulum stress in chronic restrain stressed mice; however, as an antidepressant it showed a weaker response.Graphical abstract (Source: Journal of Ayurveda and Integrative Medicine)
Source: Journal of Ayurveda and Integrative Medicine - January 9, 2019 Category: Complementary Medicine Source Type: research

Treatment of acute avulsion of posterior cruciate ligament of left knee with bony fragment by Siddha Varmam therapy and traditional bone setting method: A case report
Publication date: Available online 8 January 2019Source: Journal of Ayurveda and Integrative MedicineAuthor(s): S. Natarajan, C. Anbarasi, R. Meena, S.D. Muralidass, P. Sathiyarajeswaran, K. Gopakumar, R.S. RamaswamyAbstractA 42-year-old man with the complaints of left knee swelling, severe pain, difficult to stand was reported to Siddha Varmam division after a road accident. He was diagnosed as acute avulsion of Posterior cruciate ligament (PCL). It was diagnosed based on the history of trauma, knee pain and swelling after trauma, positive posterior drawer test and avulsion fracture shown by radiograph. He was treated wit...
Source: Journal of Ayurveda and Integrative Medicine - January 9, 2019 Category: Complementary Medicine Source Type: research

Ameliorative role of antioxidant supplementation on sodium-arsenite induced adverse effects on the developing rat cerebellum
ConclusionOur results support the potential of ALA and Cur in amelioration of iAs induced developmental neurotoxicity. ALA and Cur can be proposed as dietary adjuvants amongst populations inhabiting areas with high iAs contamination as a safe and cost effective antidotes. (Source: Journal of Ayurveda and Integrative Medicine)
Source: Journal of Ayurveda and Integrative Medicine - January 9, 2019 Category: Complementary Medicine Source Type: research

A review on the therapeutic effects of NetiKriya with special reference to JalaNeti
Publication date: Available online 5 January 2019Source: Journal of Ayurveda and Integrative MedicineAuthor(s): S. Meera, M. Vandana Rani, Cijith Sreedhar, Delvin T. RobinAbstractNeti kriya is an integral part of shatkarmas/the six cleansing techniques that form the most important aspect of hatha yoga. Neti helps in preventing and managing upper respiratory tract diseases. An attempt is being made to collate and review articles that highlight the therapeutic effects of neti kriya. Databases like PubMed (January 1980–April 2016), Scopus and Ayush Portal were searched. We used keywords like jala neti, neti kriya, neti comb...
Source: Journal of Ayurveda and Integrative Medicine - January 5, 2019 Category: Complementary Medicine Source Type: research