Quadratus lumborum block provides significant pain relief after abdominal transplant
We present contrasting experiences with a gentleman who underwent transplantation for Crohn's disease and his retransplantation with the addition of post-operative anterior Quadratus Lumborum (QL) block. After the index procedure, he had significant pain and discomfort. The addition of the QL block lead to substantial improvement in both subjective and objective endpoints. While each case is different, a QL block can be a useful adjunct to achieve pain control, decrease opioid requirements, and potentially facilitate early extubation. (Source: Journal of Anaesthesiology Clinical Pharmacology)
Source: Journal of Anaesthesiology Clinical Pharmacology - February 17, 2020 Category: Anesthesiology Authors: Christopher Adam Godlewski Source Type: research

The use of extended release bupivacaine with transversus abdominis plane and subcostal anterior quadratus lumborum catheters: A retrospective analysis of a novel technique
Conclusion: LB can be injected through a peripheral nerve catheter to prolong analgesia after catheter removal. (Source: Journal of Anaesthesiology Clinical Pharmacology)
Source: Journal of Anaesthesiology Clinical Pharmacology - February 17, 2020 Category: Anesthesiology Authors: Hesham Elsharkawy Wael Saasouh Yoon Jeong Cho Loran Mounir Soliman Jean-Louis Horn Source Type: research

Erenumab: A novel calcitonin gene-related peptide receptor antagonist developed specifically for migraine prevention
Shuchita Garg, Malti Vij, Neeraj Edward, Brinder VijJournal of Anaesthesiology Clinical Pharmacology 2020 36(1):104-109 Headaches and migraines continue to be a leading cause of suffering and disability. As per the Global Burden of Disease Survey conducted in 2010, the exact magnitude of the disease still is underestimated. Migraine alone continues to rank seventh as a cause of disability. Various therapeutic modalities exist and newer classes of medications are currently being trialed to provide effective treatment to this population of patients. Erenumab, a calcitonin gene-related peptide receptor inhibitor, is a recent...
Source: Journal of Anaesthesiology Clinical Pharmacology - February 17, 2020 Category: Anesthesiology Authors: Shuchita Garg Malti Vij Neeraj Edward Brinder Vij Source Type: research

Hydroxyethyl starch should not be used for cesarean section to prevent maternal hypotension following spinal anesthesia
Günther Putz, Christian J WiedermannJournal of Anaesthesiology Clinical Pharmacology 2020 36(1):102-103 (Source: Journal of Anaesthesiology Clinical Pharmacology)
Source: Journal of Anaesthesiology Clinical Pharmacology - February 17, 2020 Category: Anesthesiology Authors: G & #252;nther Putz Christian J Wiedermann Source Type: research

To sniff or not to sniff: The eternal debate
Riniki Sarma, Nishkarsh Gupta, Anju GuptaJournal of Anaesthesiology Clinical Pharmacology 2020 36(1):100-101 (Source: Journal of Anaesthesiology Clinical Pharmacology)
Source: Journal of Anaesthesiology Clinical Pharmacology - February 17, 2020 Category: Anesthesiology Authors: Riniki Sarma Nishkarsh Gupta Anju Gupta Source Type: research

Postoperative urinary retention: A controlled trial of fixed-dose spinal anesthesia using bupivacaine versus ropivacaine
Conclusions: Time to void urine and recovery of motor functions were found comparable statistically when bupivacaine and ropivacaine were used in the doses of 12.5 and 18.75 mg, respectively, for SA. However, group ropivacaine required lesser time to void and no patient developed POUR. Time to void urine was more than the time for ambulation. This may indicate a need for “selective spinal anesthesia” or adjuvant combination technique to accelerate the resolution of a block for ambulatory surgery. (Source: Journal of Anaesthesiology Clinical Pharmacology)
Source: Journal of Anaesthesiology Clinical Pharmacology - February 17, 2020 Category: Anesthesiology Authors: Shahla Haleem Ahmad Ozair Abhishek Singh Muazzam Hasan Manazir Athar Source Type: research

Perioperative risk factors for pulmonary complications after non-cardiac surgery
Conclusion: We found 5% incidence of PPC in our study. Recognition of the delineated risk factors and routine use of ARISCAT score for preoperative assessment may help identify patients at a higher risk of developing postoperative pulmonary complications. (Source: Journal of Anaesthesiology Clinical Pharmacology)
Source: Journal of Anaesthesiology Clinical Pharmacology - February 17, 2020 Category: Anesthesiology Authors: Surbhi Gupta Roshan Joseph Fernandes Joseph Sushil Rao Radhika Dhanpal Source Type: research

Comparison of the efficacy of two doses of dexmedetomidine in attenuating the hemodynamic response to intubation in patients undergoing elective cardiac surgery: A randomized double-blinded study
Conclusion: Dexmedetomidine in a dose of 1 μg/kg is more effective than 0.5 μg/kg for attenuation of hemodynamic stress response to intubation in cardiac surgery. A more graded increase in the dose of dexmedetomidine may lead to an optimum dose in attenuating the hemodynamic response to intubation. (Source: Journal of Anaesthesiology Clinical Pharmacology)
Source: Journal of Anaesthesiology Clinical Pharmacology - February 17, 2020 Category: Anesthesiology Authors: Annedath R Silpa KA Koshy Arun Subramanian Kizakke K Pradeep Source Type: research

Effects of intravenous dexmedetomidine on spinal anesthesia and sedation & #8211; A comparison of two different maintenance infusions
Conclusion: IV dexmedetomidine bolus of 0.5 mcg/kg prior to subarachnoid block followed by maintenance infusion of 0.5 mcg/kg/h significantly prolonged duration of motor block, time for two segment regression, along with stable hemodynamics and adequate sedation. (Source: Journal of Anaesthesiology Clinical Pharmacology)
Source: Journal of Anaesthesiology Clinical Pharmacology - February 17, 2020 Category: Anesthesiology Authors: Pritee H Bhirud Shrividya Chellam Mandar N Mote Pratibha V Toal Source Type: research

Evaluation of postoperative analgesic efficacy and perioperative hemodynamic changes with low dose intravenous dexmedetomidine infusion in patients undergoing laparoscopic cholecystectomy & #8211; A randomised, double-blinded, placebo-controlled trial
Conclusion: Dexmedetomidine IV in an infusion dose of 0.5 μg/kg/hr is effective in providing postoperative analgesia in terms of significant reduction in analgesic consumption in 24 hours and in addition to the effective obtundation of the pneumoperitoneum-induced hemodynamic changes. (Source: Journal of Anaesthesiology Clinical Pharmacology)
Source: Journal of Anaesthesiology Clinical Pharmacology - February 17, 2020 Category: Anesthesiology Authors: Geetanjali T Chilkoti Ganeshan Karthik Rajesh Rautela Source Type: research

Efficacy of multimodal analgesia with perineural buprenorphine or dexmedetomidine for surgeries performed under ultrasound-guided infraclavicular brachial plexus block
Conclusion: For surgeries under brachial plexus block, perineural dexmedetomidine when used as a part of MMA provided a prolonged duration of postoperative analgesia and improved block characteristics than perineural buprenorphine. (Source: Journal of Anaesthesiology Clinical Pharmacology)
Source: Journal of Anaesthesiology Clinical Pharmacology - February 17, 2020 Category: Anesthesiology Authors: Prashant A Lomate Manohar V Mane Source Type: research

Assessment of head and neck position for optimal ultrasonographic visualisation of the internal jugular vein and its relation to the common carotid artery: a prospective observational study
Conclusion: There is a wide variation in anatomical location of the IJV in relation to the CCA as seen by USG. Excessive head rotation causes overlap of IJV over CCA which may cause inadvertent arterial puncture, even under USG guidance. Thus, it is preferable to cannulate the IJV in neutral or near neutral head and neck position. (Source: Journal of Anaesthesiology Clinical Pharmacology)
Source: Journal of Anaesthesiology Clinical Pharmacology - February 17, 2020 Category: Anesthesiology Authors: Gaurav Purohit Rangraj Setlur Mridul Dhar Sidharth Bhasin Source Type: research

Comparative evaluation of success of ultrasound-guided internal jugular vein cannulation using needle with guard: A randomized, controlled study
Conclusions: The use of measured guided needle with guard significantly improved the accuracy, success and ease of USG guided IJV cannulation and decreased complications. (Source: Journal of Anaesthesiology Clinical Pharmacology)
Source: Journal of Anaesthesiology Clinical Pharmacology - February 17, 2020 Category: Anesthesiology Authors: Vikas Arya Devendra Gupta Anil Agarwal Mekhala Paul Prabhaker Mishra Source Type: research

Urapidil in the Preoperative treatment of pheochromocytoma: How safe is it ?
Abhishek Kumar, Nishkarsh Gupta, Anju GuptaJournal of Anaesthesiology Clinical Pharmacology 2020 36(1):55-56 (Source: Journal of Anaesthesiology Clinical Pharmacology)
Source: Journal of Anaesthesiology Clinical Pharmacology - February 17, 2020 Category: Anesthesiology Authors: Abhishek Kumar Nishkarsh Gupta Anju Gupta Source Type: research

Peri-operative management of pheochromocytoma with intravenous urapidil to prevent hemodynamic instability: A 17-year experience
Conclusion: IV urapidil limits hypertensive and hypotensive peaks during PCC surgery, and corresponds to surgical imperatives allowing a short hospital stay, due to its “on–off” effect. (Source: Journal of Anaesthesiology Clinical Pharmacology)
Source: Journal of Anaesthesiology Clinical Pharmacology - February 17, 2020 Category: Anesthesiology Authors: Patrick Tauzin-Fin K & #233;vin Barrucand Musa Sesay St & #233;phanie Roullet Philippe Gosse Jean-Christophe Bernhard Gregoire Robert Fran & #231;ois Sztark Source Type: research