Simulation of Mental Disorders: II. Computer Models, Purposes and Future Directions.
Authors: Gold A, Dudai Y Abstract The complexity of the human brain and the difficulties in identifying and dissecting the biological, social and contextual underpinnings of mental functions confound the study of the etiology and pathophysiology of mental disorders. Simulating mental disorders in animal models or in computer programs may contribute to the understanding of such disorders. In the companion paper (30), we discussed selected concepts and pragmatics pertaining to mental illness simulation in general, and then focused on issues pertaining to animal models of mental disease. In this paper, we foc...
Source: Israel Journal of Psychiatry and Related Sciences - January 14, 2017 Category: Psychiatry Tags: Isr J Psychiatry Relat Sci Source Type: research

Academic-Industry Partnerships in Alcohol and Gambling: a Continuum of Benefits and Harms.
Authors: Stein DJ Abstract There are many reasons why collaboration between academic institutions and private industry should be encouraged. At the same time, such collaborations raise the potential for profound conflicts of interest. Furthermore, there may be different kinds of issues in different kinds of industry, as is reflected in the metaphors we employ to think about them. The pharmaceutical industry is at times viewed as a "good" industry that can go wrong, while the tobacco industry is analogously viewed as a "bad" industry that can do little right. The alcohol and gambling industries may be parti...
Source: Israel Journal of Psychiatry and Related Sciences - October 4, 2015 Category: Psychiatry Tags: Isr J Psychiatry Relat Sci Source Type: research

Differential Associations Between Depression, Risk Factors for Insulin Resistance and Diabetes Incidence in a Large U.S. Sample.
CONCLUSIONS: Lack of physical activity, hypertension, and inadequate sleep were the risk factors for insulin resistance with the highest associations with both depression and diabetes incidence. PMID: 26431411 [PubMed - in process] (Source: Israel Journal of Psychiatry and Related Sciences)
Source: Israel Journal of Psychiatry and Related Sciences - October 4, 2015 Category: Psychiatry Tags: Isr J Psychiatry Relat Sci Source Type: research

Psychopathology and its Early Impact on Parenting Behaviors in Mothers: The Interface between Adult and Infant Psychiatry.
Authors: Keren M, Tyano S Abstract Parenting is, in its essence, the domain where adult mental health and infant's mental and physical health meet in a complex and dynamic interplay. Becoming a parent is a developmental challenge in itself, and often exacerbates an existing mental illness, and in turn, maladaptive parenting impinges on the early parent-infant relationship, and on the infant's socio-emotional development and later functioning. The capacity for mentalization is brought as a bridging concept between adult and infant psychiatry. A few clinical vignettes illustrate the dynamic interplay between...
Source: Israel Journal of Psychiatry and Related Sciences - October 4, 2015 Category: Psychiatry Tags: Isr J Psychiatry Relat Sci Source Type: research

The Outcome of Severe Internalizing and Disruptive Disorders from Preschool into Adolescence:A Follow-up Study.
CONCLUSION: The trajectories of severe psychiatric disorders at preschool years are similar to those reported in community samples and differ according to the baseline diagnosis. Children with internalizing disorders show a much better recovery rate than those with comorbid disruptive and internalizing disorders. PMID: 26431413 [PubMed - in process] (Source: Israel Journal of Psychiatry and Related Sciences)
Source: Israel Journal of Psychiatry and Related Sciences - October 4, 2015 Category: Psychiatry Tags: Isr J Psychiatry Relat Sci Source Type: research

Feasibility of a Dual Evaluation/Intervention Program for Morbidly Obese Adolescents.
CONCLUSIONS: The findings support the feasibility of our dual screening/intervention protocol. Measures to improve parental participation are warranted. PMID: 26431414 [PubMed - in process] (Source: Israel Journal of Psychiatry and Related Sciences)
Source: Israel Journal of Psychiatry and Related Sciences - October 4, 2015 Category: Psychiatry Tags: Isr J Psychiatry Relat Sci Source Type: research

Dental Health and the Type of Antipsychotic Treatment in Inpatients with Schizophrenia.
CONCLUSIONS: The results suggest that patients with schizophrenia maintained on atypicals have better dental health than patients treated with typicals or with a combination of both. From an oral health perspective, monotherapy with atypicals is superior to both typical and atypical/typical treatments. Although the choice between typical and atypical antipsychotic agents is based mainly on clinical psychiatric efficacy, the benefit of atypicals with regard to dental health should be taken into consideration in clinician's decision making. PMID: 26431415 [PubMed - in process] (Source: Israel Journal of Psychiatry and Related Sciences)
Source: Israel Journal of Psychiatry and Related Sciences - October 4, 2015 Category: Psychiatry Tags: Isr J Psychiatry Relat Sci Source Type: research

Severity of Psychiatric Disorders and Dental Health Among Psychiatric Outpatients in Jerusalem, Israel.
Authors: Cooper-Kazaz R, Levy DH, Zini A, Sgan-Cohen HD Abstract The association between severity of psychiatric disorder and dental disease has not been adequately studied. The aim of the present study was to examine the level of dental caries morbidity and the association with Severe Mental Illness (SMI) and mild/moderate psychiatric disorders. The population sample included patients aged 30 to 50, treated at the Hadassah psychiatric outpatient clinic, after giving written informed consent. Exclusion criteria included eating disorders which are recognized as being associated with several dental pathologi...
Source: Israel Journal of Psychiatry and Related Sciences - October 4, 2015 Category: Psychiatry Tags: Isr J Psychiatry Relat Sci Source Type: research

Validation of the HCR-20 Scale for Assessing Risk of Violent Behavior in Israeli Psychiatric Inpatients.
CONCLUSIONS: Appropriate psychometric properties of the HCR-20 suggest that it can serve as a useful measure of the risk of violent behavior in psychiatric settings in Israel. Further research is necessary to confirm norms and cut-off scores, using a larger representative sample. PMID: 26431417 [PubMed - in process] (Source: Israel Journal of Psychiatry and Related Sciences)
Source: Israel Journal of Psychiatry and Related Sciences - October 4, 2015 Category: Psychiatry Tags: Isr J Psychiatry Relat Sci Source Type: research

Negative and Positive Automatic thoughts in Social Anxiety Disorder.
CONCLUSIONS: Automatic thoughts may be an important area of research with larger samples. Further studies should be carried out in order to examine if strengthening positive thinking and ablation of negative thinking can reduce SAD symptoms during cognitive behavioral treatment. PMID: 26431418 [PubMed - in process] (Source: Israel Journal of Psychiatry and Related Sciences)
Source: Israel Journal of Psychiatry and Related Sciences - October 4, 2015 Category: Psychiatry Tags: Isr J Psychiatry Relat Sci Source Type: research

Voluntary Departure of Family Physicians from their Workplace: A Reflective Outlook.
CONCLUSION: Qualitative analysis revealed that the voluntary departure of the family physician has complex personal and systemic implications. PRACTICAL IMPLICATIONS: The combination of Balint group discussions and written reflections can help the physician better cope with the departure and also help patients and staff deal with the separation process. PMID: 26431419 [PubMed - in process] (Source: Israel Journal of Psychiatry and Related Sciences)
Source: Israel Journal of Psychiatry and Related Sciences - October 4, 2015 Category: Psychiatry Tags: Isr J Psychiatry Relat Sci Source Type: research

A pilot open study of long term high dose creatine augmentation in patients with treatment resistant negative symptoms schizophrenia.
CONCLUSION: This small, open design study of high dose creatine add-on for 6 months in chronic inpatients with schizophrenia demonstrated only mild positive effects on the patients' symptomatology and behavior and might have beneficial effect on tardive parkinsonism. PMID: 25841104 [PubMed - in process] (Source: Israel Journal of Psychiatry and Related Sciences)
Source: Israel Journal of Psychiatry and Related Sciences - June 4, 2015 Category: Psychiatry Tags: Isr J Psychiatry Relat Sci Source Type: research

Safety, tolerability and pharmacokinetics of open label sarcosine added on to anti-psychotic treatment in schizophrenia - preliminary study.
CONCLUSIONS: Sarcosine is a safe compound and might be efficacious in the treatment of schizophrenia. PMID: 25841105 [PubMed - in process] (Source: Israel Journal of Psychiatry and Related Sciences)
Source: Israel Journal of Psychiatry and Related Sciences - June 4, 2015 Category: Psychiatry Tags: Isr J Psychiatry Relat Sci Source Type: research

Long-term Follow-up of MDD Patients Who Respond to Deep rTMS: A Brief Report.
CONCLUSION: Relapse rates after dTMS are comparable to pharmacotherapy and ECT. PMID: 25841106 [PubMed - in process] (Source: Israel Journal of Psychiatry and Related Sciences)
Source: Israel Journal of Psychiatry and Related Sciences - June 4, 2015 Category: Psychiatry Tags: Isr J Psychiatry Relat Sci Source Type: research

Suicides among persons with psychiatric hospitalizations.
CONCLUSION: This study highlights the importance of suicide prevention interventions for persons both during their inpatient stay and who were expected to be followed up in community-based facilities. PMID: 25841107 [PubMed - in process] (Source: Israel Journal of Psychiatry and Related Sciences)
Source: Israel Journal of Psychiatry and Related Sciences - June 4, 2015 Category: Psychiatry Tags: Isr J Psychiatry Relat Sci Source Type: research