Management of HPV ‐Positive Women in Cervical Screening Using Results from Two Consecutive Screening Rounds
We studied whether triage of human papillomavirus (HPV) ‐positive women participating in an HPV‐based screening programme can be improved by including the HPV result at the previous screen in the triage algorithm.We analyzed data of a subgroup of 366 women from the POBASCAM trial, screened by cytology and HPV co ‐testing. Women were included if they tested HPV‐positive in the second HPV‐based screening round. We evaluated the clinical performance of sixteen strategies, consisting of cytology, HPV genotyping, and/or previous screen HPV result. The clinical endpoint was cervical precancer or cancer (CIN 3+).The cur...
Source: International Journal of Cancer - November 22, 2018 Category: Cancer & Oncology Authors: Nicole J. Polman,
Nienke J. Veldhuijzen,
Dani ëlle. A.M. Heideman,
Peter J.F. Snijders,
Chris J.L.M. Meijer,
Johannes Berkhof Tags: Research Article Source Type: research
Overweight in midlife and risk of cancer in late life: a nationwide Swedish twin study
In conclusion, midlife overweight is associated with increased risk of late‐life colon, liver, and uterine cancer but reduced risk of late‐life non‐melanoma skin cancer. Further investigations are warranted t o explore the role of genetic and early‐life environmental factors in these associations.This article is protected by copyright. All rights reserved. (Source: International Journal of Cancer)
Source: International Journal of Cancer - November 22, 2018 Category: Cancer & Oncology Authors: Cuiping Bao,
Rongrong Yang,
Nancy L Pedersen,
Weige Xu,
Hui Xu,
Ruixue Song,
Xiuying Qi,
Weili Xu Tags: Research Article Source Type: research
Relationship of DNA methylation to mutational changes and transcriptional organization in fusion ‐positive and fusion‐negative rhabdomyosarcoma
In conclusion, these findings highlight the interaction of epigenetic changes with mutational alterations and transcriptional organizati on in RMS tumors, and contribute to improved molecular categorization of these tumors.This article is protected by copyright. All rights reserved. (Source: International Journal of Cancer)
Source: International Journal of Cancer - November 22, 2018 Category: Cancer & Oncology Authors: Wenyue Sun,
Bishwanath Chatterjee,
Jack F. Shern,
Rajesh Patidar,
Young Song,
Yonghong Wang,
Robert L. Walker,
Bruce R. Pawel,
Corinne M. Linardic,
Peter Houghton,
Stephen M. Hewitt,
Daniel C. Edelman,
Javed Khan,
Paul S. Meltzer,
Frederic G Tags: Research Article Source Type: research
Alterations in the Gut Microbiota and Metabolite Profiles of Thyroid Carcinoma Patients
In conclusion, this study presents a comprehensive landscape of the gut microbiota and metabolites in TC patients, and provides a research direction of the mechanism of interaction between gut microbiota alteration and TC pathogenesis.This article is protected by copyright. All rights reserved. (Source: International Journal of Cancer)
Source: International Journal of Cancer - November 22, 2018 Category: Cancer & Oncology Authors: Jing Feng,
Fuya Zhao,
Jiayu Sun,
Baiqiang Lin,
Lei Zhao,
Yang Liu,
Ye Jin,
Shengda Li,
Aidong Li,
Yunwei Wei Tags: Research Article Source Type: research
An effective dendritic cell ‐based vaccine containing glioma stem‐like cell lysate and CpG adjuvant for an orthotopic mouse model of glioma
This study aimed to assess the therapeutic efficacy of a glioma vaccine called STDENVANT. This vaccine, comprising glioma stem ‐like cell (GSC) lysate, dendritic cells (DCs), and Toll‐like receptor (TLR) 9 agonist CpG motif‐containing oligodeoxynucleotides (CpG ODNs), was assessed using a GL261‐C57BL/6 orthotopic mouse model of glioma. STDENVANT markedly improved survival and tumor regression by enhancing anti‐tum or immune function. Moreover, STDENVANT upregulated programmed death 1 (PD‐1) and its ligand PD‐L1 on effector T cells, DCs, and glioma tissues, resulting in the accumulation of regulatory T (Treg) ...
Source: International Journal of Cancer - November 22, 2018 Category: Cancer & Oncology Authors: Shan Zhu,
Xinping Lv,
Xuhao Zhang,
Tete Li,
Guoxia Zang,
Ning Yang,
Xue Wang,
Jing Wu,
Wei Chen,
Yong ‐Jun Liu,
Jingtao Chen Tags: Research Article Source Type: research
Fecal microbiota transplantation in cancer management: Current status and perspectives
This article would help to better understand this new therapeutic approach for cancer patients by targeting gut microbiota.This article is protected by copyright. All rights reserved. (Source: International Journal of Cancer)
Source: International Journal of Cancer - November 20, 2018 Category: Cancer & Oncology Authors: Danfeng Chen,
Jingyi Wu,
Duochen Jin,
Bangmao Wang,
Hailong Cao Tags: Mini Review Source Type: research
Molecular and cellular basis of mammary gland fibrosis and cancer risk
This article is protected by copyright. All rights reserved. (Source: International Journal of Cancer)
Source: International Journal of Cancer - November 19, 2018 Category: Cancer & Oncology Authors: Jianchun Wu,
David L. Crowe Tags: Research Article Source Type: research
CTCs ‐derived xenograft development in a Triple Negative breast cancer case
This article is protected by copyright. All rights reserved. (Source: International Journal of Cancer)
Source: International Journal of Cancer - November 19, 2018 Category: Cancer & Oncology Authors: Tais Pereira ‐Veiga,
Manuel Abreu,
Diego Robledo,
Xavier Matias‐Guiu,
María Santacana,
Laura Sánchez,
Juan Cueva,
Patricia Palacios,
Ihab Abdulkader,
Rafael López‐López,
Laura Muinelo‐Romay,
Clotilde Costa Tags: Research Article Source Type: research
Erratum
International Journal of Cancer, EarlyView. (Source: International Journal of Cancer)
Source: International Journal of Cancer - November 18, 2018 Category: Cancer & Oncology Tags: Erratum Source Type: research
Long non ‐coding RNA MIR31HG is a bona fide prognostic marker with colorectal cancer cell‐intrinsic properties
This article is protected by copyright. All rights reserved. (Source: International Journal of Cancer)
Source: International Journal of Cancer - November 17, 2018 Category: Cancer & Oncology Authors: Peter W. Eide,
Ina A. Eilertsen,
Anita Sveen,
Ragnhild A. Lothe Tags: Research Article Source Type: research
Measurement of Tumor Mutational Burden (TMB) in routine molecular diagnostics: in ‐silico and real‐life analysis of three larger gene panels
This article is protected by copyright. All rights reserved. (Source: International Journal of Cancer)
Source: International Journal of Cancer - November 17, 2018 Category: Cancer & Oncology Authors: Volker Endris,
Ivo Buchhalter,
Michael Allg äuer,
Eugen Rempel,
Amelie Lier,
Anna‐Lena Volckmar,
Martina Kirchner,
Moritz Winterfeld,
Jonas Leichsenring,
Olaf Neumann,
Roland Penzel,
Wilko Weichert,
Hanno Glimm,
Stefan Fröhling,
Hauke Wi Tags: Research Article Source Type: research
Integrated epigenomic and transcriptomic analysis reveals TP63 as a novel player in clinically aggressive chronic lymphocytic leukemia
In conclusion, we report that DNA methylation profiles may vary even among CLL patients with similar somatic hypermutation status, supporting a compartmentalized approach to dissecting CLL biology. Furthermore, we highlight p63 as a novel prosurvival factor in CLL, thus identifying ano ther piece of the complex puzzle of clinical aggressiveness.This article is protected by copyright. All rights reserved. (Source: International Journal of Cancer)
Source: International Journal of Cancer - November 16, 2018 Category: Cancer & Oncology Authors: Nikos Papakonstantinou,
Stavroula Ntoufa,
Maria Tsagiopoulou,
Theodoros Moysiadis,
Sujata Bhoi,
Andigoni Malousi,
Fotis Psomopoulos,
Larry Mansouri,
Stamatia Laidou,
Despoina Papazoglou,
Maria Gounari,
Konstantinos Pasentsis,
Karla Plevova,
V Tags: Research Article Source Type: research
Challenges in Assessing the Sunscreen ‐Melanoma Association
This article is protected by copyright. All rights reserved. (Source: International Journal of Cancer)
Source: International Journal of Cancer - November 16, 2018 Category: Cancer & Oncology Authors: Corina S Rueegg,
Jo S Stenehjem,
Matthias Egger,
Reza Ghiasvand,
Eunyoung Cho,
Eiliv Lund,
Elisabete Weiderpass,
Adele C Green,
Marit B Veier ød Tags: Research Article Source Type: research
Issue Information
International Journal of Cancer, Volume 143, Issue 11, Page 3041-3042, 1 December 2018. (Source: International Journal of Cancer)
Source: International Journal of Cancer - November 14, 2018 Category: Cancer & Oncology Tags: Issue Information Source Type: research
Issue Information
International Journal of Cancer, Volume 143, Issue 11, Page 2617-2627, 1 December 2018. (Source: International Journal of Cancer)
Source: International Journal of Cancer - November 14, 2018 Category: Cancer & Oncology Tags: Issue Information Source Type: research
