Andexanet controlled factor Xa inhibitor–related bleeding
The factor Xa antidote andexanet achieved effective hemostasis 12 hours after infusion in 79% of patients who had developed serious acute bleeding on factor Xa inhibitor therapy, according to a... (Source: Hospitalist News)
Source: Hospitalist News - August 30, 2016 Category: Hospital Management Source Type: research

NSTEMI mortality decline attributed to invasive therapies
Invasive coronary therapies deserve credit for the decade-long decline in mortality among patients hospitalized with NSTEMI in the United Kingdom, Marlous Hall, PhD, said at the annual meeting of the... (Source: Hospitalist News)
Source: Hospitalist News - August 30, 2016 Category: Hospital Management Source Type: research

VIDEO: Smell test reflects brain pathologies, risk of Alzheimer’s progression
TORONTO – A scratch-and-sniff test that asks subjects to identify 40 odors and ranks olfaction is almost as powerful a predictor of Alzheimer’s disease as is a positive test for amyloid. Low scores... (Source: Hospitalist News)
Source: Hospitalist News - August 29, 2016 Category: Hospital Management Source Type: research

VIDEO: Moderate LDL, SBP reductions slash cardiovascular events 90% over time
ROME – Combined exposure to low LDL cholesterol and systolic blood pressure is associated with multiplicative and cumulative effects over time, Brian A. Ference, MD, said in a video interview at the... (Source: Hospitalist News)
Source: Hospitalist News - August 29, 2016 Category: Hospital Management Source Type: research

VIDEO: ICDs cut mortality in younger, healthier heart failure patients
ROME – Implantable cardioverter-defibrillators failed to significantly cut total mortality in patients with nonischemic systolic heart failure in the first large, randomized trial designed... (Source: Hospitalist News)
Source: Hospitalist News - August 29, 2016 Category: Hospital Management Source Type: research

Novel treatment strategy to reduce infarct size in STEMI
ROME – Early administration of high-dose N-acetylcysteine and low-dose glyceryl trinitrate in ST-segment elevation acute myocardial infarction (STEMI) patients undergoing primary percutaneous... (Source: Hospitalist News)
Source: Hospitalist News - August 29, 2016 Category: Hospital Management Source Type: research

Antibiotics overprescribed during asthma-related hospitalizations
Antibiotics are overprescribed in asthma-related hospitalizations, even though guidelines recommend against prescribing antibiotics during exacerbations of asthma in the absence of concurrent... (Source: Hospitalist News)
Source: Hospitalist News - August 28, 2016 Category: Hospital Management Source Type: research

Host RNA biosignatures distinguish bacterial from viral fever
RNA-expression biosignatures derived from the patient’s peripheral blood distinguish bacterial from viral causes of fever in young children, according to two separate preliminary studies published... (Source: Hospitalist News)
Source: Hospitalist News - August 27, 2016 Category: Hospital Management Source Type: research

No VTE prophylaxis needed after joint surgery in patients with hemophilia
ORLANDO – In patients with hemophilia who have therapeutic factor levels at the time of joint replacement surgery, prophylaxis against venous thromboembolism (VTE) may be unnecessary. In a cohort... (Source: Hospitalist News)
Source: Hospitalist News - August 27, 2016 Category: Hospital Management Source Type: research

Flu vaccine prevented hospitalizations in patients 50 and older
The seasonal influenza vaccination reduced flu-related hospitalizations by 56.8% among people aged 50 and older during a recent flu season, according to a report published in Clinical Infectious... (Source: Hospitalist News)
Source: Hospitalist News - August 27, 2016 Category: Hospital Management Source Type: research

Hospital medicine
It is important to step back occasionally to survey where one has been and to plot a new heading. In an online Aug. 10, 2016, release, the New England Journal of Medicine posted two opinion pieces... (Source: Hospitalist News)
Source: Hospitalist News - August 24, 2016 Category: Hospital Management Source Type: research

Clinical decision tree pinpointed risk of extended-spectrum beta-lactamase bacteremia
A new classification tool helped guide the treatment of bacteremic patients while clinicians awaited antibiotic resistance results, investigators reported. The clinical decision tree had a positive... (Source: Hospitalist News)
Source: Hospitalist News - August 24, 2016 Category: Hospital Management Source Type: research

Rotavirus vaccine again linked to small increase in risk of intussusception hospitalization
The first dose of rotavirus vaccine was again linked to a small, short-term increase in the risk of hospitalization for intussusception, but the benefits of the vaccine exceed this risk, according to... (Source: Hospitalist News)
Source: Hospitalist News - August 24, 2016 Category: Hospital Management Source Type: research

Decision Support in Medicine: Septic Arthritis
1. Overview: What every practitioner needs to knowAre you sure your patient has infectious arthritis? What should you expect to find?The symptoms, signs and... (Source: Hospitalist News)
Source: Hospitalist News - August 24, 2016 Category: Hospital Management Source Type: research

Multifocal effort needed to rein in prescription prices
Enforcing more stringent requirements for exclusivity rights, ensuring timely generic drug availability, and providing greater opportunities for meaningful price negotiation by government payers... (Source: Hospitalist News)
Source: Hospitalist News - August 23, 2016 Category: Hospital Management Source Type: research