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Hematological Oncology, Ahead of Print. (Source: Hematological Oncology)
Source: Hematological Oncology - February 14, 2018 Category: Hematology Source Type: research
Intestinal T ‐cell lymphoma with enteropathy‐associated T‐cell lymphoma‐like features arising in the setting of adult autoimmune enteropathy
Abstract
Enteropathy‐associated T‐cell lymphoma is regarded as a dismal, late complication of coeliac disease, though a single case of T‐cell lymphoma with such features arising in the setting of autoimmune enteropathy of the adult has been reported to date. We aim to describe the case of a 41‐year‐old woman complaining of severe malabsorption syndrome, who was diagnosed with autoimmune enteropathy based on the presence of flat intestinal mucosa unresponsive to any dietary restriction and positivity for enterocyte autoantibodies. Steroid therapy led to a complete recovery of both mucosal and clinical findings ove...
Source: Hematological Oncology - February 14, 2018 Category: Hematology Authors: Rachele Ciccocioppo, Giorgio A. Croci, Federico Biagi, Alessandro Vanoli, Costanza Alvisi, Giorgio Cavenaghi, Roberta Riboni, Mariarosa Arra, Paolo G. Gobbi, Marco Paulli, Gino R. Corazza Tags: CASE REPORT Source Type: research
Monocyte subsets and their phenotypes during treatment with BCR ‐ABL1 tyrosine kinase inhibitors for Philadelphia chromosome‐positive leukemia
Hematological Oncology, EarlyView. (Source: Hematological Oncology)
Source: Hematological Oncology - February 12, 2018 Category: Hematology Source Type: research
Continuously infused amphotericin B deoxycholate for primary treatment of invasive fungal disease in acute myeloid leukaemia
Hematological Oncology, EarlyView. (Source: Hematological Oncology)
Source: Hematological Oncology - February 12, 2018 Category: Hematology Source Type: research
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Hematological Oncology, Ahead of Print. (Source: Hematological Oncology)
Source: Hematological Oncology - February 12, 2018 Category: Hematology Source Type: research
Continuously infused amphotericin B deoxycholate for primary treatment of invasive fungal disease in acute myeloid leukaemia
Abstract
Continuous administration of amphotericin B deoxycholate over 24 hours (24 h‐D‐AmB) is better tolerated than rapid infusions. However, toxicity and outcome have not been assessed in a homogenous patient population with acute myeloid leukaemia (AML). We retrospectively analysed renal function and outcome in all adult patients with AML undergoing intensive chemotherapy between 2007 and 2012 at our institution. We compared a patient group with exposure to 24 h‐D‐AmB to a patient group without exposure to 24 h‐D‐AmB. One hundred and eighty‐one consecutive patients were analysed, 133 (73.5%) received ...
Source: Hematological Oncology - February 12, 2018 Category: Hematology Authors: Christoph Rothenb ühler, Ulrike Held, Markus G. Manz, Urs Schanz, Bernhard Gerber Tags: ORIGINAL RESEARCH ARTICLE Source Type: research
Comments on “Clinical characteristics of chronic lymphocytic leukemia occurring in Chornobyl cleanup workers” by S.C. Finch, I. Dyagil et al., Vol. 35 (2), 2017, p. 215‐224
Hematological Oncology, EarlyView. (Source: Hematological Oncology)
Source: Hematological Oncology - February 2, 2018 Category: Hematology Source Type: research
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Hematological Oncology, Ahead of Print. (Source: Hematological Oncology)
Source: Hematological Oncology - February 2, 2018 Category: Hematology Source Type: research
Atypical chronic myeloid leukaemia: A case of an orphan disease —A multicenter report by the Polish Adult Leukemia Group
Abstract
Atypical chronic myeloid leukaemia (aCML) belongs to myelodysplastic/myeloproliferative neoplasms. Because of its rarity and changing diagnostic criteria throughout subsequent classifications, data on aCML are very scarce. Therefore, we at the Polish Adult Leukemia Group performed a nationwide survey on aCML. Eleven biggest Polish centres participated in the study. Altogether, 45 patients were reported, among whom only 18 patients (40%) fulfilled diagnostic criteria. Among misdiagnosed patients, myelodysplastic/myeloproliferative syndrome unclassifiable and chronic myelomonocytic leukaemia were the most frequent d...
Source: Hematological Oncology - February 1, 2018 Category: Hematology Authors: Joanna Drozd ‐Sokołowska, Krzysztof Mądry, Anna Waszczuk‐Gajda, Przemysław Biecek, Paweł Szwedyk, Katarzyna Budziszewska, Magdalena Raźny, Magdalena Dutka, Agata Obara, Ewa Wasilewska, Krzysztof Lewandowski, Agnieszka Piekarska, Grażyna Bober, H Tags: ORIGINAL RESEARCH ARTICLE Source Type: research
Clinical, pathological, and biological characterization of Richter syndrome developing after ibrutinib treatment for relapsed chronic lymphocytic leukemia
Abstract
Richter syndrome, a transformation of chronic lymphocytic leukemia (CLL) into a diffuse large B‐cell lymphoma, is a rare complication of patients treated with chemo‐immunotherapy. Richter syndrome might be both clonally related or unrelated to the underlying CLL and often showed mutations of the TP53 and NOTCH1 genes. Recently, ibrutinib was approved for patients with relapsed/refractory CLL or for untreated CLL patients with del 17p or TP53 mutation. The clinical picture, pathology, and genetics of Richter transformation after IBR treatment are largely unknown. Here, we report 2 cases of Richter transformatio...
Source: Hematological Oncology - February 1, 2018 Category: Hematology Authors: Idanna Innocenti, Davide Rossi, Giulio Trap è, Francesco Autore, Luigi Maria Larocca, Vincenzo Gomes, Michaela Cerri, Paolo Falcucci, Simona Sica, Gianluca Gaidano, Luca Laurenti Tags: CASE REPORT Source Type: research
Presence of autoimmune disease affects not only risk but also survival in patients with B ‐cell non‐Hodgkin lymphoma
We examined associations between autoimmunity and B‐cell NHL onset by comparing AID history (determined by self‐report and medication review and supplemented by chart review where possible) among 435 adult B‐NHL patients in Hadassah‐Hebrew University Medical Center, diagnosed 2009‐2014, and 414 age‐and‐sex frequency‐matched controls. We examined AIDs as a whole, B‐ and T‐cell–mediated AIDs, and autoimmune thyroid diseases. Among cases, we used Kaplan‐Meier and Cox regression models to assess the association of AID with overall survival and relapse‐free survival, adjusting for prognostically import...
Source: Hematological Oncology - February 1, 2018 Category: Hematology Authors: Geffen Kleinstern, Mor Averbuch, Rania Abu Seir, Riki Perlman, Dina Ben Yehuda, Ora Paltiel Tags: ORIGINAL RESEARCH ARTICLE Source Type: research
Chemical and thyroid hormone profile of the bone marrow interstitial fluid in hematologic disorders and patients without primary hematologic disorders
Hematological Oncology, EarlyView. (Source: Hematological Oncology)
Source: Hematological Oncology - January 30, 2018 Category: Hematology Source Type: research
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Hematological Oncology, Ahead of Print. (Source: Hematological Oncology)
Source: Hematological Oncology - January 30, 2018 Category: Hematology Source Type: research
Prolonged survival after second autologous transplantation and lenalidomide maintenance for salvage treatment of myeloma patients at first relapse after prior autograft
Hematological Oncology, EarlyView. (Source: Hematological Oncology)
Source: Hematological Oncology - January 24, 2018 Category: Hematology Source Type: research
