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Basic Considerations for the Use of Monoclonal Antibodies in Migraine
ConclusionsThe CGRP mAbs are an innovative new therapy for migraine and address the need for effective and tolerable preventive options. MAbs, including those that target CGRP or its receptor, bind to a target with high specificity and affinity and lead to few off ‐target adverse effects, although mechanism‐based adverse reactions may occur. Unlike other therapeutic antibodies used to treat neurologic disease, CGRP mAbs do not have a target within the immune system and have been designed to avoid altering the immune system. The safety and efficacy of mAbs against CGRP or its receptors are being investigated in clinical...
Source: Headache: The Journal of Head and Face Pain - November 13, 2018 Category: Neurology Authors: Morris Levin, Stephen D. Silberstein, Robert Gilbert, Sylvia Lucas, Leanne Munsie, Alyssa Garrelts, Kate Kennedy, Nicole Everman, Eric Pearlman Tags: Headache Currents Source Type: research

Incidence of Persistent Headache at 18 Months Following Accidental Dural Puncture in the Obstetric Population: A Prospective Service Evaluation in 45 Patients
ConclusionPost dural puncture headache from an accidental dural puncture can no longer be considered a self ‐limiting condition. Current evidence probably mandates the addition of persistent headache as one of the potential complications of an epidural insertion during informed consent process. (Source: Headache: The Journal of Head and Face Pain)
Source: Headache: The Journal of Head and Face Pain - November 13, 2018 Category: Neurology Authors: Priya Gauthama, Aditi Kelkar, Siti M.A. Basar, G. Niraj Tags: Brief Communications Source Type: research

Migraine Treatment in Pregnant Women Presenting to Acute Care: A Retrospective Observational Study
ConclusionsWhile the majority of pregnant women with acute migraine received medications considered relatively safe in pregnancy, there was variation in treatment choice and sequence. Some acute medications considered potentially hazardous for fetal health and less effective for migraine (opioids and butalbital) were used frequently, whereas other treatments that may have low teratogenic risk (nerve blocks, IV fluid boluses, and triptans) were used less or not at all. These results indicate a need for developing guidelines and protocols to standardize acute treatment of migraine in pregnancy. (Source: Headache: The Journal...
Source: Headache: The Journal of Head and Face Pain - November 7, 2018 Category: Neurology Authors: Katherine T. Hamilton, Matthew S. Robbins Tags: Research Submission Source Type: research

Anti ‐Calcitonin Gene‐Related Peptide (CGRP) Therapies: Update on a Previous Review After the American Headache Society 60th Scientific Meeting, San Francisco, June 2018
ConclusionsThe development of anti ‐CGRP therapies opens a new era in the acute and preventive treatment of primary headache disorders. (Source: Headache: The Journal of Head and Face Pain)
Source: Headache: The Journal of Head and Face Pain - November 7, 2018 Category: Neurology Authors: Stewart J. Tepper Tags: Review Article Source Type: research

Issue Information
Headache: The Journal of Head and Face Pain, Volume 58, Issue S3, November 2018. (Source: Headache: The Journal of Head and Face Pain)
Source: Headache: The Journal of Head and Face Pain - November 7, 2018 Category: Neurology Tags: Issue Information Source Type: research

The Headache Cooperative of New England (HCNE) Symposium on Calcitonin Gene ‐Related Peptide
Headache: The Journal of Head and Face Pain, Volume 58, Issue S3, Page 217-217, November 2018. (Source: Headache: The Journal of Head and Face Pain)
Source: Headache: The Journal of Head and Face Pain - November 7, 2018 Category: Neurology Authors: Alan M. Rapoport Tags: Editorial Source Type: research

Erratum
Headache: The Journal of Head and Face Pain, EarlyView. (Source: Headache: The Journal of Head and Face Pain)
Source: Headache: The Journal of Head and Face Pain - November 7, 2018 Category: Neurology Tags: Erratum Source Type: research

CGRP, Amylin, Immunology, and Headache Medicine
Headache: The Journal of Head and Face Pain, EarlyView. (Source: Headache: The Journal of Head and Face Pain)
Source: Headache: The Journal of Head and Face Pain - November 3, 2018 Category: Neurology Authors: Frederick R. Taylor Source Type: research

Sleep Disorders Among People With Migraine: Results From the Chronic Migraine Epidemiology and Outcomes (CaMEO) Study
Headache: The Journal of Head and Face Pain, EarlyView. (Source: Headache: The Journal of Head and Face Pain)
Source: Headache: The Journal of Head and Face Pain - November 1, 2018 Category: Neurology Authors: Dawn C. Buse, Jeanetta C. Rains, Jelena M. Pavlovic, Kristina M. Fanning, Michael L. Reed, Aubrey Manack Adams, Richard B. Lipton Source Type: research

When Mom Has Migraine: An Observational Study of the Impact of Parental Migraine on Adolescent Children
Headache: The Journal of Head and Face Pain, EarlyView. (Source: Headache: The Journal of Head and Face Pain)
Source: Headache: The Journal of Head and Face Pain - October 31, 2018 Category: Neurology Authors: Elizabeth K. Seng, Emily D. Mauser, Maya Marzouk, Zarine S. Patel, Noah Rosen, Dawn C. Buse Source Type: research

Recurrent Painful Cranial Neuropathy in a Child Involving Multiple Cranial Nerves
Headache: The Journal of Head and Face Pain, EarlyView. (Source: Headache: The Journal of Head and Face Pain)
Source: Headache: The Journal of Head and Face Pain - October 31, 2018 Category: Neurology Authors: Dinesh Lulla, Deniz Altinok, Lalitha Sivaswamy Source Type: research

Health care Resource Utilization and Migraine Disability Along the Migraine Continuum Among Patients Treated for Migraine
Headache: The Journal of Head and Face Pain, EarlyView. (Source: Headache: The Journal of Head and Face Pain)
Source: Headache: The Journal of Head and Face Pain - October 30, 2018 Category: Neurology Authors: Stephen D. Silberstein, Lulu Lee, Kavita Gandhi, Timothy Fitzgerald, Jvawnna Bell, Joshua M. Cohen Source Type: research

Development of a New Tool for Evaluating the Benefit of Preventive Treatments for Migraine on Functional Outcomes – The Migraine Functional Impact Questionnaire (MFIQ)
Headache: The Journal of Head and Face Pain, EarlyView. (Source: Headache: The Journal of Head and Face Pain)
Source: Headache: The Journal of Head and Face Pain - October 30, 2018 Category: Neurology Authors: Asha Hareendran, Anne Skalicky, Sally Mannix, Sara Lavoie, Pooja Desai, Martha Bayliss, Andrew V. Thach, Daniel D. Mikol, Dawn C. Buse Source Type: research

Barriers to Behavioral Treatment Adherence for Headache: An Examination of Attitudes, Beliefs, and Psychiatric Factors
Headache: The Journal of Head and Face Pain, EarlyView. (Source: Headache: The Journal of Head and Face Pain)
Source: Headache: The Journal of Head and Face Pain - October 27, 2018 Category: Neurology Authors: Yuka Matsuzawa, Yuen Shan Christine Lee, Felicia Fraser, Donna Langenbahn, Amanda Shallcross, Scott Powers, Richard Lipton, Naomi Simon, Mia Minen Source Type: research

High Achievement Motivation is Not Related to Increased Use of Acute Headache Medication in Migraine: A Cross ‐sectional Observational Cohort Study
Headache: The Journal of Head and Face Pain, EarlyView. (Source: Headache: The Journal of Head and Face Pain)
Source: Headache: The Journal of Head and Face Pain - October 27, 2018 Category: Neurology Authors: Verena Sorgenfrei, Peter Kropp, Andreas Straube, Ruth Ruscheweyh Source Type: research