Insulin glargine/lixisenatide fixed ‐ratio combination improves glycaemic variability and control without increasing hypoglycaemia
This article is protected by copyright. All rights reserved. (Source: Diabetes, Obesity and Metabolism)
Source: Diabetes, Obesity and Metabolism - November 13, 2018 Category: Endocrinology Authors: Ronnie Aronson,
Guillermo Umpierrez,
William Stager,
Boris Kovatchev Tags: BRIEF REPORT Source Type: research
Diabetes, Obesity and Metabolism
, Volume 20, Issue 12, Page 2709-2710, December 2018. (Source: Diabetes, Obesity and Metabolism)
Source: Diabetes, Obesity and Metabolism - November 11, 2018 Category: Endocrinology Tags: ISSUE INFORMATION Source Type: research
GlucoTab ‐guided insulin therapy using insulin glargine U300 enables glycaemic control with low risk of hypoglycaemia in hospitalized patients with type 2 diabetes
ConclusionsTreatment with GlucoTab using insulin glargine U300 in hospitalized patients with T2D is effective and safe. (Source: Diabetes, Obesity and Metabolism)
Source: Diabetes, Obesity and Metabolism - November 11, 2018 Category: Endocrinology Authors: Felix Aberer,
Katharina M. Lichtenegger,
Edin Smajic,
Klaus Donsa,
Oliver Malle,
Judith Samonigg,
Bernhard H öll,
Peter Beck,
Thomas R. Pieber,
Johannes Plank,
Julia K. Mader Tags: ORIGINAL ARTICLE Source Type: research
The relationships between markers of tubular injury and intrarenal haemodynamic function in adults with and without type 1 diabetes: Results from the Canadian Study of Longevity in Type 1 Diabetes
ConclusionsElevated NGAL relates to intrarenal haemodynamic dysfunction in T1D, whereas elevated NGAL and B2M relate to intrarenal haemodynamic dysfunction in adults without T1D. These data may define a diabetes ‐specific interplay between tubular injury and intrarenal haemodynamic dysfunction. (Source: Diabetes, Obesity and Metabolism)
Source: Diabetes, Obesity and Metabolism - November 11, 2018 Category: Endocrinology Authors: Petter Bjornstad,
Sunita K. Singh,
Janet K. Snell ‐Bergeon,
Julie A. Lovshin,
Yuliya Lytvyn,
Leif E. Lovblom,
Marian J. Rewers,
Genevieve Boulet,
Vesta Lai,
Josephine Tse,
Leslie Cham,
Andrej Orszag,
Alanna Weisman,
Hillary A. Keenan,
Mich Tags: ORIGINAL ARTICLE Source Type: research
Reduction in Albuminuria With Dapagliflozin Cannot Be Predicted by Baseline Clinical Characteristics or Changes in Most Other Risk Markers
This article is protected by copyright. All rights reserved. (Source: Diabetes, Obesity and Metabolism)
Source: Diabetes, Obesity and Metabolism - November 9, 2018 Category: Endocrinology Authors: Hiddo J.L. Heerspink,
C. David Sj öström,
Silvio E. Inzucchi,
Melissa K. Hallow,
Valerie A. Cain,
Peter Rossing,
Bergur V. Stefansson,
Peter Sartipy Tags: BRIEF REPORT Source Type: research
Hypoglycaemia as a function of HbA1c in type 2 diabetes: Insulin glargine 300 U/mL in a patient ‐level pooled analysis of EDITION 1, 2 and 3
This article is protected by copyright. All rights reserved. (Source: Diabetes, Obesity and Metabolism)
Source: Diabetes, Obesity and Metabolism - November 9, 2018 Category: Endocrinology Authors: Riccardo C. Bonadonna,
Jean ‐François Yale,
Claire Brulle‐Wohlhueter,
Emmanuelle Boëlle‐Le Corfec,
Pratik Choudhary,
Timothy S. Bailey Tags: BRIEF REPORT Source Type: research
What the diabetes data in FOURIER trial fail to show
This article is protected by copyright. All rights reserved. (Source: Diabetes, Obesity and Metabolism)
Source: Diabetes, Obesity and Metabolism - November 8, 2018 Category: Endocrinology Authors: F.H. van Bruggen,
H. J. Luijendijk Tags: LETTER TO THE EDITOR Source Type: research
SGLT2 inhibitor regulates ketone body metabolism via inter ‐organ crosstalk
ConclusionsSGLT2i increased systemic and tissue BHB levels by upregulating ketogenic enzymes and transporters in the liver, kidney, and intestine, suggesting the integrated physiological consequences in ketone body metabolism by SGLT2i administration.This article is protected by copyright. All rights reserved. (Source: Diabetes, Obesity and Metabolism)
Source: Diabetes, Obesity and Metabolism - November 8, 2018 Category: Endocrinology Authors: Jin Hee Kim,
Minyoung Lee,
Soo Hyun Kim,
So Ra Kim,
Byung ‐Wan Lee,
Eun Seok Kang,
Bong‐Soo Cha,
Jin Won Cho,
Yong‐ho Lee Tags: ORIGINAL ARTICLE Source Type: research
Effect of switching from pioglitazone to the sodium glucose co ‐transporter‐2 inhibitor dapagliflozin on body weight and metabolism‐related factors in patients with type 2 diabetes mellitus: An open‐label, prospective, randomized, parallel‐group comparison trial
The effects of dapagliflozin (DAP) and pioglitazone (PIO) on body weight and glycaemic control were compared in patients with type 2 diabetes mellitus. Seventy ‐one patients on PIO were either switched to DAP (n = 36) at 5 mg per day or continued on PIO (n = 35). Primary endpoints were superiority of body weight loss and non‐inferiority of HbA1c level after 24 weeks with DAP. Body weight decrease was greater with DAP than with PIO (75.3 ± 14.9 to 71.3 ± 15.1 kg vs. 74.7 ± 13.8 to 75.2 ± 13.9 kg;P < 0.01). Change in the HbA1c level was comparable (P = 0.64). The level of N‐te...
Source: Diabetes, Obesity and Metabolism - November 8, 2018 Category: Endocrinology Authors: Kyu Yong Cho,
Akinobu Nakamura,
Kazuno Omori,
Takahiro Takase,
Aika Miya,
Naoki Manda,
Yoshio Kurihara,
Shin Aoki,
Tatsuya Atsumi,
Hideaki Miyoshi Tags: BRIEF REPORT Source Type: research
Corrigendum
Diabetes, Obesity and Metabolism, EarlyView. (Source: Diabetes, Obesity and Metabolism)
Source: Diabetes, Obesity and Metabolism - November 8, 2018 Category: Endocrinology Tags: CORRIGENDUM Source Type: research
Prevalence and progression of diabetic nephropathy in South Asians, White Europeans and Afro ‐Caribbeans with Type 2 diabetes; a systematic review and meta‐analysis
ConclusionThis review did not find a significant link between ethnicity (South Asians, White Europeans and Afro ‐Caribbeans) and the prevalence of microalbuminuria. However, the incident rate ratio of end stage renal disease in African Caribbeans compared to White Europeans was significantly higher. Further research is needed to explore the potential non‐albuminuric pathways of progression to end stage re nal failure.This article is protected by copyright. All rights reserved. (Source: Diabetes, Obesity and Metabolism)
Source: Diabetes, Obesity and Metabolism - November 8, 2018 Category: Endocrinology Authors: Chandni Jadawji,
Winston Crasto,
Clare Gillies,
Debasish Kar,
Melanie J Davies,
Kamlesh Khunti,
Samuel Seidu Tags: ORIGINAL ARTICLE Source Type: research
Achieving LDL ‐C target levels less than 70 mg/dL may provide extra cardiovascular protection in high‐risk patients: exploratory analysis of the Standard Versus Intensive Statin Therapy for Patients With Hypercholesterolemia and Diabetic Retinopathy Study
Diabetes, Obesity and Metabolism,Volume 0, Issue ja, -Not available-. (Source: Diabetes, Obesity and Metabolism)
Source: Diabetes, Obesity and Metabolism - November 5, 2018 Category: Endocrinology Authors: Hiroshi Itoh,
Issei Komuro,
Masahiro Takeuchi,
Takashi Akasaka,
Hiroyuki Daida,
Yoshiki Egashira,
Hideo Fujita,
Jitsuo Higaki,
Ken ‐ichi Hirata,
Shun Ishibashi,
Takaaki Isshiki,
Sadayoshi Ito,
Atsunori Kashiwagi,
Satoshi Kato,
Kazuo Kitaga Source Type: research
Double ‐blind, randomized clinical trial comparing the efficacy and safety of continuing or discontinuing the dipeptidyl peptidase‐4 inhibitor sitagliptin when initiating insulin glargine therapy in patients with type 2 diabetes: The CompoSIT‐I Study
Diabetes, Obesity and Metabolism,Volume 0, Issue ja, -Not available-. (Source: Diabetes, Obesity and Metabolism)
Source: Diabetes, Obesity and Metabolism - November 5, 2018 Category: Endocrinology Authors: Ronan Roussel,
Santiago Dur án García,
Yilong Zhang,
Suneri Shah,
Carolyn Darmiento,
R. Ravi Shankar,
Gregory T. Golm,
Raymond L.H. Lam,
Edward A. O'Neill,
Ira Gantz,
Keith D. Kaufman,
Samuel S. Engel Source Type: research
CANadian CAnagliflozin Registry: Effectiveness and Safety of Canagliflozin in the treatment of Type 2 diabetes mellitus in Canadian Clinical Practice
Diabetes, Obesity and Metabolism,Volume 0, Issue ja, -Not available-. (Source: Diabetes, Obesity and Metabolism)
Source: Diabetes, Obesity and Metabolism - November 5, 2018 Category: Endocrinology Authors: Vincent Woo,
Alan Bell,
Maureen Clement,
Luis Noronha,
Michael A. Tsoukas,
Fernando Camacho,
Shana Traina,
Natasha Georgijev,
Matthew D. Culham,
Jennifer B. Rose,
Wally Rapattoni,
Harpreet S. Bajaj Source Type: research
Follistatins in glucose regulation of healthy and obese subjects
Diabetes, Obesity and Metabolism,Volume 0, Issue ja, -Not available-. (Source: Diabetes, Obesity and Metabolism)
Source: Diabetes, Obesity and Metabolism - November 5, 2018 Category: Endocrinology Authors: Nikolaos Perakakis,
Alexander Kokkinos,
Natia Peradze,
Nicholas Tentolouris,
Wael Ghaly,
Dimitrios Tsilingiris,
Andreas Alexandrou,
Christos S. Mantzoros Source Type: research
