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Protein Adsorption: A Quest for a Universal Mechanism
Publication date: Available online 29 November 2018Source: Current Opinion in Colloid & Interface ScienceAuthor(s): Zbigniew AdamczykAbstractDespite extensive research effort, the understanding of protein adsorption phenomena still remains incomplete. Discrepancies persist concerning the nature of driving forces, reversibility of adsorption, extent of conformational changes, etc. However, this is not due to the lack of reliable experimental and theoretical results but rather to their inadequate interpretation. Accordingly, in this work, experimental results obtained for well-defined systems using direct experimental techni...
Source: Current Opinion in Colloid and Interface Science - November 29, 2018 Category: Chemistry Source Type: research

Protein - surface interactions at the Nanoscale: atomistic simulations with implicit solvent models
Publication date: Available online 24 November 2018Source: Current Opinion in Colloid & Interface ScienceAuthor(s): David C. Malaspina, Leonor Pérez-Fuentes, Carlos Drummond, Delfi Bastos-González, Jordi FaraudoAbstractA full molecular-level understanding of protein adsorption in important situations such as the formation of protein films at solid/liquid interfaces or the formation of a protein corona over inorganic nanoparticles is still lacking. All-atomic implicit solvent molecular dynamics (MD) simulations, which are successfully employed in many related protein studies (such as protein folding for example) are emerg...
Source: Current Opinion in Colloid and Interface Science - November 24, 2018 Category: Chemistry Source Type: research

Colloids and surfaces in biology
Publication date: Available online 22 November 2018Source: Current Opinion in Colloid & Interface ScienceAuthor(s): Martin Malmsten, Stefan Zauscher (Source: Current Opinion in Colloid and Interface Science)
Source: Current Opinion in Colloid and Interface Science - November 22, 2018 Category: Chemistry Source Type: research

Machine Learning Antimicrobial Peptide Sequences:Some Surprising Variations on the Theme of Amphiphilic Assembly
Publication date: Available online 16 November 2018Source: Current Opinion in Colloid & Interface ScienceAuthor(s): Michelle W. Lee, Ernest Y. Lee, Andrew L. Ferguson, Gerard C.L. WongAbstractAntimicrobial peptides (AMPs) collectively constitute a key component of the host innate immune system. They span a diverse space of sequences and can be α-helical, β-sheet, or unfolded in structure. Despite a wealth of knowledge about them from decades of experiments, it remains difficult to articulate general principles governing such peptides. How are they different from other molecules that are also cationic and amphiphilic? Wha...
Source: Current Opinion in Colloid and Interface Science - November 17, 2018 Category: Chemistry Source Type: research

Biosynthetic Transition Metal Chalcogenide Semiconductor Nanoparticles: Progress in Synthesis, Property Control and Applications
Publication date: Available online 16 November 2018Source: Current Opinion in Colloid & Interface ScienceAuthor(s): Yaying Feng, Katherine E. Marusak, Lingchong You, Stefan ZauscherAbstractTransition metal (TM) chalcogenides are a group of semiconductor materials with applications that range from antibacterial particles to thin films in energy conversion devices. Significant progress in synthetic biology combined with the benefits of low energy consumption and low toxic waste burden of “green synthesis,” have directed considerable research attention to the biosynthesis of these inorganic materials. TM chalcogenide nano...
Source: Current Opinion in Colloid and Interface Science - November 16, 2018 Category: Chemistry Source Type: research