CME Questions
(Source: Comprehensive Therapy)
Source: Comprehensive Therapy - December 1, 2007 Category: Primary Care Source Type: research

Pulmonary Arterial Hypertension
Abstract Better recognition of primary pulmonary hypertension can produce better treatment by comprehensive therapists. (Source: Comprehensive Therapy)
Source: Comprehensive Therapy - December 1, 2007 Category: Primary Care Source Type: research

Radiation Therapy for Prostate Cancer: The Role for Dose Escalation
Recent technological advances in radiation treatment delivery have allowed relatively higher doses of radiation to be delivered safely to the prostate. Emerging data suggest improvements in disease control with higher doses of radiation in subsets of patients with prostate cancer. (Source: Comprehensive Therapy)
Source: Comprehensive Therapy - December 1, 2007 Category: Primary Care Source Type: research

Treatment of Heart Failure with Normal Left Ventricular Ejection Fraction
Underlying causes and precipitating causes of heart failure (HF) should be treated when possible. Persons with HF and normal left ventricular ejection fraction (LVEF) should have maintenance of sinus rhythm, treatment of hypertension, myocardial ischemia, dyslipidemia, and anemia, slowing of the ventricular rate below 90 bpm, and reduction of salt overload. First-line drug treatment in the management of these persons is the use of loop diuretics combined with beta blockers and angiotensin-converting enzyme (ACE) inhibitors. If persons are unable to tolerate ACE inhibitors because of cough, angioneurotic edema, rash, or al...
Source: Comprehensive Therapy - December 1, 2007 Category: Primary Care Source Type: research

Diagnosis and Management of Pleural Effusions: A Practical Approach
Pleural effusion is defined as an abnormal amount of pleural fluid accumulation in the pleural space and is the result of an imbalance between excessive pleural fluid formation and pleural fluid absorption. Although the list of causes of pleural effusions is extensive, the great majority of the cases are caused by pneumonia, congestive heart failure, and malignancy. In this article, we provide an overview of the most common causes of pleural effusions likely to be encountered by the general practitioner, and a practical approach to the diagnosis and management of this common condition. (Source: Comprehensive Therapy)
Source: Comprehensive Therapy - December 1, 2007 Category: Primary Care Source Type: research

Posttraumatic Stress Disorder in Primary Care Patients
Posttraumatic stress disorder (PTSD) is a common psychiatric condition. PTSD patients can present with a wide variety of symptoms, and these patients are also at a higher risk of other physical, psychiatric, and substance abuse problems. Recent advances in the treatment of this condition can help the majority of patients with PTSD. Early detection, initiation of appropriate treatment, and timely referral are crucial in the proper management of PTSD. (Source: Comprehensive Therapy)
Source: Comprehensive Therapy - December 1, 2007 Category: Primary Care Source Type: research

Pulmonary Embolism—A State of the Clot Review
Abstract The assessment for pulmonary emboli is still Stone Age. History and physical findings are not sensitive or specific making it difficult to establish the diagnosis. PE is still potentially fatal. Death most often results from the severity of the clot, although delay in treatment may play a role. Clots, including deep venous thrombosis and pulmonary emboli, are the first disease that falls clearly under the Hospitalist specialty. An argument over what imaging is ideal continues to rage on, without any clear leader at this point. The CT scan and Ventilation/Perfusion scan are the two modalities be...
Source: Comprehensive Therapy - December 1, 2007 Category: Primary Care Source Type: research

Book Reviews
(Source: Comprehensive Therapy)
Source: Comprehensive Therapy - December 1, 2007 Category: Primary Care Source Type: research

Editorial
(Source: Comprehensive Therapy)
Source: Comprehensive Therapy - December 1, 2007 Category: Primary Care Source Type: research

Pulmonary Embolism —A State of the Clot Review
< h3 class= " a-plus-plus " > Abstract < /h3 > < p class= " a-plus-plus " > The assessment for pulmonary emboli is still Stone Age. History and physical findings are not sensitive or specific making it difficult to establish the diagnosis. PE is still potentially fatal. Death most often results from the severity of the clot, although delay in treatment may play a role. Clots, including deep venous thrombosis and pulmonary emboli, are the first disease that falls clearly under the Hospitalist specialty. An argument over what imaging is ideal continues to rage on, without any clear leader at this point. The CT scan and Venti...
Source: Comprehensive Therapy - November 30, 2007 Category: Primary Care Source Type: research

Cardiovascular Manifestations Seen in Obstructive Sleep Apnea
Patients with obstructive sleep apnea (OSA) have an increased prevalence of systemic and pulmonary hypertension, left ventricular (LV) hypertrophy, LV systolic and diastolic dysfunction, and congestive heart failure, increased platelet aggregability, and increased susceptibility to thrombotic and embolic cardiac and cerebrovascular events. Patients with OSA have an increased prevalence of coronary artery disease, myocardial infarction, nocturnal angina, and myocardial ischemia, arrhythmias, and sudden cardiac death. Patients with OSA also have an increased prevalence of stroke. Treatment of OSA with continuous positive air...
Source: Comprehensive Therapy - September 27, 2007 Category: Primary Care Source Type: research

Acute Retinal Necrosis Complicating Chickenpox in a Healthy Adult —A Case Report and Review of Literature
We report a case of unilateral ARN with marked vitritis and retinal necrosis leading to retinal breaks following chickenpox in a 32-year-old healthy lady. This patient was successfully treated with intravenous acyclovir followed by oral acyclovir and orbital floor triamcinolone injections to contain the inflammation with barrier laser therapy to secure the retinal breaks with good visual outcome. This case is unusual in its severity, and to our knowledge, orbital floor triamcinolone therapy was not used earlier to contain ARN inflammation. (Source: Comprehensive Therapy)
Source: Comprehensive Therapy - September 1, 2007 Category: Primary Care Source Type: research

A Man with Tropical Travel History, Fever, and Pulmonary Infiltrates
Acute Respiratory Distress Syndrome (ARDS) are one of the most serious complications of falciparum malaria. Pathogenesis of ARDS along with factors contributing towards the development and treatment of ARDS is discussed. (Source: Comprehensive Therapy)
Source: Comprehensive Therapy - September 1, 2007 Category: Primary Care Source Type: research

Treatment of Postmenopausal Osteoporosis
AbstractOsteoporosis is a skeletal disease characterized by low bone mass and microarchitectural deterioration with a resulting increase in bone fragility and hence susceptibility to fracture. Calcium and vitamin D are the most commonly used therapies for osteoporosis, although their efficacy in osteoporotic fracture prevention remains uncertain. Biphosphonates are the most frequently prescribed medication for treatment of osteoporosis and are often considered as first-line therapy for the treatment of osteoporosis. Currently, hormone replacement therapy is only approved by the Food and Drug Administration (FDA) for short-...
Source: Comprehensive Therapy - September 1, 2007 Category: Primary Care Source Type: research