Acute and Chronic Leukemias
Slideset - Elias Jabbour, MD, and Farhad Ravandi, MD, review key studies and data presented at the 2015 American Society of Hematology Annual Meeting relevant to the management of patients with acute leukemias and chronic leukemias. (Source: Clinical Care Options Leukemia)
Source: Clinical Care Options Leukemia - January 11, 2016 Category: Hematology Source Type: research

Evaluating Efficacy and Safety of Allo-SCT and Prognostic Value of MRD-Negative CR After 19-28z CAR T-Cell Infusion in Patients With R/R B-Cell ALL
Slideset - MRD-negative CR following 19-28z CAR T-cell infusion associated with superior OS. (Source: Clinical Care Options Leukemia)
Source: Clinical Care Options Leukemia - December 18, 2015 Category: Hematology Source Type: research

Pracinostat + Azacitidine in Elderly Patients With Newly Diagnosed AML
Slideset - Early data suggest potential clinical benefit from this combination. (Source: Clinical Care Options Leukemia)
Source: Clinical Care Options Leukemia - December 15, 2015 Category: Hematology Source Type: research

Venetoclax Monotherapy in R/R CLL With del(17p)
Slideset - Single-agent venetoclax is active and achieved deep responses in relapsed/refractory CLL with del(17p). (Source: Clinical Care Options Leukemia)
Source: Clinical Care Options Leukemia - December 14, 2015 Category: Hematology Source Type: research

Blinatumomab After AlloHSCT in Patients With R/R B-Precursor ALL
Slideset - In a subanalysis of a phase II trial, patients with R/R B-precursor ALL after alloHSCT achieved a 45% CR/CRh rate with blinatumomab treatment. (Source: Clinical Care Options Leukemia)
Source: Clinical Care Options Leukemia - December 14, 2015 Category: Hematology Source Type: research

Rigosertib + Azacitidine in Patients With Higher-Risk MDS
Slideset - Data from this small study suggest rigosertib plus azacitidine therapy may be effective and safe in this setting. (Source: Clinical Care Options Leukemia)
Source: Clinical Care Options Leukemia - December 14, 2015 Category: Hematology Source Type: research

Blinatumomab for MRD-Positive B-Cell Precursor ALL: An 18-Month Follow-up
Slideset - Patients with complete MRD response after blinatumomab treatment had prolonged OS, RFS, and DoR vs those with an incomplete MRD response. (Source: Clinical Care Options Leukemia)
Source: Clinical Care Options Leukemia - December 14, 2015 Category: Hematology Source Type: research

Long-term Follow-up of CD19-Targeted CAR-T Cells (CTL019) in Pediatric Patients With Relapsed/Refractory ALL
Slideset - Potent and durable antitumor activity seen in pediatric patients with relapsed/refractory ALL. (Source: Clinical Care Options Leukemia)
Source: Clinical Care Options Leukemia - December 13, 2015 Category: Hematology Source Type: research

Phase III RESONATE-2: Frontline Ibrutinib vs Chlorambucil in Elderly Patients With CLL
Slideset - In this phase III trial that enrolled elderly treatment-naive patients with CLL, ibrutinib was associated with significant reductions in risk of progression and death vs chlorambucil. (Source: Clinical Care Options Leukemia)
Source: Clinical Care Options Leukemia - December 12, 2015 Category: Hematology Source Type: research

Understanding the Needs of Younger Patients With Acute Lymphoblastic Leukemia
CCO Slideset - In this downloadable slideset, Lauri A. Linder, PhD, APRN, CPON, provides a case-based overview of current nursing considerations in the management of adolescent and young adult patients with acute lymphoblastic leukemia. (Source: Clinical Care Options Oncology - Leukemia)
Source: Clinical Care Options Oncology - Leukemia - May 2, 2013 Category: Hematology Source Type: research

Acute Leukemias and Myelodysplastic Syndromes
CCO Slideset - Farhad Ravandi, MD, and Rami S. Komrokji, MD, provide their expert perspective on results presented at the annual Hematology meeting in the settings of acute leukemias, MDS, ALL, and myeloproliferative neoplasms. (Source: Clinical Care Options Oncology - Leukemia)
Source: Clinical Care Options Oncology - Leukemia - January 18, 2013 Category: Hematology Source Type: research

Current Treatment Options for Acute Promyelocytic Leukemia
Learning Module - Farhad Ravandi, MD, discusses the current and emerging therapy options for patients with APL in several clinical scenarios. (Source: Clinical Care Options Oncology - Leukemia)
Source: Clinical Care Options Oncology - Leukemia - January 18, 2013 Category: Hematology Source Type: research

Current Treatment Options for Acute Promyelocytic Leukemia
CCO Slideset - Farhad Ravandi, MD, discusses the current and emerging therapy options for patients with APL in several clinical scenarios. (Source: Clinical Care Options Oncology - Leukemia)
Source: Clinical Care Options Oncology - Leukemia - January 18, 2013 Category: Hematology Source Type: research

Chronic Lymphocytic Leukemia
CCO Slideset - In this downloadable slideset, Susan M. O’Brien, MD, and Kanti Rai, MD, present key data on the treatment of chronic lymphocytic leukemia presented at the 2012 American Society of Hematology Annual Meeting. (Source: Clinical Care Options Oncology - Leukemia)
Source: Clinical Care Options Oncology - Leukemia - January 15, 2013 Category: Hematology Source Type: research