Design, synthesis, and biological activity evaluation of campthothecin ‐HAA‐Norcantharidin conjugates as antitumor agents in vitro
Chemical Biology&Drug Design, EarlyView. (Source: Chemical Biology and Drug Design)
Source: Chemical Biology and Drug Design - October 31, 2018 Category: Biology Authors: Xian H. Wang,
Mei Huang,
Chang K. Zhao,
Chan Li,
Lang Xu Source Type: research
Dual functions of ARP101 in targeting membrane type ‐1 matrix metalloproteinase: Impact on U87 glioblastoma cell invasion and autophagy signaling
Chemical Biology&Drug Design, EarlyView. (Source: Chemical Biology and Drug Design)
Source: Chemical Biology and Drug Design - October 31, 2018 Category: Biology Authors: Michel Desjarlais,
Borhane Annabi Source Type: research
Retraction
“si‐RNA‐Mediated Knockdown of PDLIM5 Suppresses Gastric Cancer Cell Proliferationin Vitro” by Yanliang Li, Yongsheng Gao, Yue Xu, Xianjun Sun, Xilin Song, Heng Ma& Mingshan Yang.[1]The above article fromChemical Biology& Drug Design, published online on September 12, 2014 in Wiley Online Library (http://onlinelibrary.wiley.com), and in Volume 85, pp. 447 ‐453, has been retracted by agreement between the journal Editor in Chief David Selwood, and John Wiley and Sons Ltd. The retraction has been agreed upon following the realisation that there are several serious errors with this paper with incorrect shRNA sequence...
Source: Chemical Biology and Drug Design - October 30, 2018 Category: Biology Tags: RETRACTION Source Type: research
Dual functions of ARP101 in targeting membrane type ‐1 matrix metalloproteinase: Impact on U87 glioblastoma cell invasion and autophagy signaling
Membrane type ‐1 matrix (MT1‐MMP) metalloproteinase is highly expressed in glioblastoma. Inducing cancer cell autophagy may contribute to cancer therapy. We found that ARP101 exploits MT1‐MMP's signal transducing functions to trigger autophagy in a highly invasive glioblastoma cell line model. ARP101 may be envisioned in future therapy modalities against brain cancer. AbstractMembrane type ‐1 matrix metalloproteinase (MT1‐MMP) possesses both extracellular proteolytic and intracellular signal‐transducing functions in tumorigenesis. An imbalance in MT1‐MMP expression and/or function triggers a metastatic, invas...
Source: Chemical Biology and Drug Design - October 30, 2018 Category: Biology Authors: Michel Desjarlais,
Borhane Annabi Tags: RESEARCH ARTICLE Source Type: research
Retraction
Chemical Biology&Drug Design, EarlyView. (Source: Chemical Biology and Drug Design)
Source: Chemical Biology and Drug Design - October 30, 2018 Category: Biology Source Type: research
Synthesis of 99mTc ‐roxithromycin: A novel diagnostic agent to discriminate between septic and aseptic inflammation
Roxithromycin (second ‐generation macrolide antibiotic) was labeled with gamma‐emitting radionuclide (i.e.,99mTc) to diagnose the early stage bacterial action by accumulation of the radiopharmaceutical at targeted site (infected byStaphylococcus aureus). In vivo studies of newly synthesized radiopharmaceutical illustrated that99mTc ‐roxithromycin can be used as potential infection imaging agent. AbstractRoxithromycin is a second ‐generation macrolide antibiotic derived from erythromycin. In the current study, roxithromycin (ROX) was successfully labeled with technetium‐99m for early diagnosis of bacterial infecti...
Source: Chemical Biology and Drug Design - October 29, 2018 Category: Biology Authors: Syed Faheem Askari Rizvi,
Saleha Tariq,
Muhammad Mehdi,
Ahmad Junaid Hassan Tags: SPECIAL ISSUE Source Type: research
Synthesis of 99mTc ‐roxithromycin: A novel diagnostic agent to discriminate between septic and aseptic inflammation
Chemical Biology&Drug Design, EarlyView. (Source: Chemical Biology and Drug Design)
Source: Chemical Biology and Drug Design - October 29, 2018 Category: Biology Authors: Syed Faheem Askari Rizvi,
Saleha Tariq,
Muhammad Mehdi,
Ahmad Junaid Hassan Source Type: research
N ‐Pyridin‐2‐yl Benzamide Analogues as Allosteric Activators of Glucokinase: Design, Synthesis, In Vitro, In Silico and In Vivo Evaluation
Chemical Biology&Drug Design,Volume 0, Issue ja, -Not available-. (Source: Chemical Biology and Drug Design)
Source: Chemical Biology and Drug Design - October 28, 2018 Category: Biology Authors: Ajmer Singh Grewal,
Rajeev Kharb,
Deo Nandan Prasad,
Jagdeep Singh Dua,
Viney Lather Source Type: research
Design, synthesis, and biological evaluation of quinazoline derivatives as dual HDAC1 and HDAC6 inhibitors for the treatment of cancer
Chemical Biology&Drug Design, EarlyView. (Source: Chemical Biology and Drug Design)
Source: Chemical Biology and Drug Design - October 28, 2018 Category: Biology Authors: Jinying Chen,
Zitai Sang,
Youjun Jiang,
Chao Yang,
Linhong He Source Type: research
N ‐Pyridin‐2‐yl Benzamide Analogues as Allosteric Activators of Glucokinase: Design, Synthesis, In Vitro, In Silico and In Vivo Evaluation
Chemical Biology&Drug Design,Volume 0, Issue ja, -Not available-. (Source: Chemical Biology and Drug Design)
Source: Chemical Biology and Drug Design - October 28, 2018 Category: Biology Authors: Ajmer Singh Grewal,
Rajeev Kharb,
Deo Nandan Prasad,
Jagdeep Singh Dua,
Viney Lather Source Type: research
Design, synthesis, and biological evaluation of quinazoline derivatives as dual HDAC1 and HDAC6 inhibitors for the treatment of cancer
Chemical Biology&Drug Design, EarlyView. (Source: Chemical Biology and Drug Design)
Source: Chemical Biology and Drug Design - October 28, 2018 Category: Biology Authors: Jinying Chen,
Zitai Sang,
Youjun Jiang,
Chao Yang,
Linhong He Source Type: research
Evidence of human ‐like Ca2+ Channels and Effects of Ca2+ Channel blockers in Acanthamoeba castellanii
Chemical Biology&Drug Design,Volume 0, Issue ja, -Not available-. (Source: Chemical Biology and Drug Design)
Source: Chemical Biology and Drug Design - October 26, 2018 Category: Biology Authors: Abdul Mannan Baig,
R Zohaib,
W Nuzair,
K Saiqa,
N. Mehdia Source Type: research
Design, Synthesis, Molecular Modelling and In Vitro Evaluation of Tricyclic Coumarins Against Trypanosoma Cruzi
Chemical Biology&Drug Design,Volume 0, Issue ja, -Not available-. (Source: Chemical Biology and Drug Design)
Source: Chemical Biology and Drug Design - October 26, 2018 Category: Biology Authors: Gleicekelly Silva Coelho,
Josimara Souza Andrade,
Viviane Flores Xavier,
Policarpo Ademar Sales,
Barbara Caroline Rodrigues de Araujo,
K átia da Silva Fonseca,
Melissa Soares Caetano,
Silvane Maria Fonseca Murta,
Paula Melo de Abreu Vieira,
Clau Source Type: research
Cover Image
Chemical Biology&Drug Design,Volume 92, Issue 5, Page i-i, November 2018. (Source: Chemical Biology and Drug Design)
Source: Chemical Biology and Drug Design - October 26, 2018 Category: Biology Authors: Run ‐Ze Li,
Xing‐Xing Fan,
Dan‐Feng Shi,
Guo‐Yuan Zhu,
Yu‐Wei Wang,
Lian‐Xiang Luo,
Hu‐Dan Pan,
Xiao‐Jun Yao,
Elaine Lai‐Han Leung,
Liang Liu Source Type: research
Issue Information
Chemical Biology&Drug Design,Volume 92, Issue 5, Page 1819-1821, November 2018. (Source: Chemical Biology and Drug Design)
Source: Chemical Biology and Drug Design - October 26, 2018 Category: Biology Source Type: research
