mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events
Publication date: 15 April 2021Source: Cell, Volume 184, Issue 8Author(s): Marina K. Holz, Bryan A. Ballif, Steven P. Gygi, John Blenis (Source: Cell)
Source: Cell - April 16, 2021 Category: Cytology Source Type: research
The mTORC1 pathway stimulates glutamine metabolism and cell proliferation by repressing SIRT4
Publication date: 15 April 2021Source: Cell, Volume 184, Issue 8Author(s): Alfred Csibi, Sarah-Maria Fendt, Chenggang Li, George Poulogiannis, Andrew Y. Choo, Douglas J. Chapski, Seung Min Jeong, Jamie M. Dempsey, Andrey Parkhitko, Tasha Morrison, Elizabeth P. Henske, Marcia C. Haigis, Lewis C. Cantley, Gregory Stephanopoulos, Jane Yu, John Blenis (Source: Cell)
Source: Cell - April 16, 2021 Category: Cytology Source Type: research
Alzheimer’s-causing mutations shift Aβ length by destabilizing γ-secretase-Aβn interactions
Publication date: 15 April 2021Source: Cell, Volume 184, Issue 8Author(s): Maria Szaruga, Bogdan Munteanu, Sam Lismont, Sarah Veugelen, Katrien Horré, Marc Mercken, Takaomi C. Saido, Natalie S. Ryan, Tatjana De Vos, Savvas N. Savvides, Rodrigo Gallardo, Joost Schymkowitz, Frederic Rousseau, Nick C. Fox, Carsten Hopf, Bart De Strooper, Lucía Chávez-Gutiérrez (Source: Cell)
Source: Cell - April 16, 2021 Category: Cytology Source Type: research
Glioblastomas acquire myeloid-affiliated transcriptional programs via epigenetic immunoediting to elicit immune evasion
Publication date: Available online 14 April 2021Source: CellAuthor(s): Ester Gangoso, Benjamin Southgate, Leanne Bradley, Stefanie Rus, Felipe Galvez-Cancino, Niamh McGivern, Esra Güç, Chantriolnt-Andreas Kapourani, Adam Byron, Kirsty M. Ferguson, Neza Alfazema, Gillian Morrison, Vivien Grant, Carla Blin, IengFong Sou, Maria Angeles Marques-Torrejon, Lucia Conde, Simona Parrinello, Javier Herrero, Stephan Beck (Source: Cell)
Source: Cell - April 15, 2021 Category: Cytology Source Type: research
High-precision coding in visual cortex
Publication date: Available online 14 April 2021Source: CellAuthor(s): Carsen Stringer, Michalis Michaelos, Dmitri Tsyboulski, Sarah E. Lindo, Marius Pachitariu (Source: Cell)
Source: Cell - April 15, 2021 Category: Cytology Source Type: research
ER-to-Golgi protein delivery through an interwoven, tubular network extending from ER
Publication date: Available online 13 April 2021Source: CellAuthor(s): Aubrey V. Weigel, Chi-Lun Chang, Gleb Shtengel, C. Shan Xu, David P. Hoffman, Melanie Freeman, Nirmala Iyer, Jesse Aaron, Satya Khuon, John Bogovic, Wei Qiu, Harald F. Hess, Jennifer Lippincott-Schwartz (Source: Cell)
Source: Cell - April 14, 2021 Category: Cytology Source Type: research
Reducing acetylated tau is neuroprotective in brain injury
Publication date: Available online 13 April 2021Source: CellAuthor(s): Min-Kyoo Shin, Edwin Vázquez-Rosa, Yeojung Koh, Matasha Dhar, Kalyani Chaubey, Coral J. Cintrón-Pérez, Sarah Barker, Emiko Miller, Kathryn Franke, Maria F. Noterman, Divya Seth, Rachael S. Allen, Cara T. Motz, Sriganesh Ramachandra Rao, Lara A. Skelton, Machelle T. Pardue, Steven J. Fliesler, Chao Wang, Tara E. Tracy, Li Gan (Source: Cell)
Source: Cell - April 14, 2021 Category: Cytology Source Type: research
Synthetic lethality-mediated precision oncology via the tumor transcriptome
Publication date: Available online 14 April 2021Source: CellAuthor(s): Joo Sang Lee, Nishanth Ulhas Nair, Gal Dinstag, Lesley Chapman, Youngmin Chung, Kun Wang, Sanju Sinha, Hongui Cha, Dasol Kim, Alexander V. Schperberg, Ajay Srinivasan, Vladimir Lazar, Eitan Rubin, Sohyun Hwang, Raanan Berger, Tuvik Beker, Ze’ev Ronai, Sridhar Hannenhalli, Mark R. Gilbert, Razelle Kurzrock (Source: Cell)
Source: Cell - April 14, 2021 Category: Cytology Source Type: research
Programmable protein circuit design
Publication date: Available online 12 April 2021Source: CellAuthor(s): Zibo Chen, Michael B. Elowitz (Source: Cell)
Source: Cell - April 14, 2021 Category: Cytology Source Type: research
Kinase-mediated RAS signaling via membraneless cytoplasmic protein granules
Publication date: Available online 12 April 2021Source: CellAuthor(s): Asmin Tulpule, Juan Guan, Dana S. Neel, Hannah R. Allegakoen, Yone Phar Lin, David Brown, Yu-Ting Chou, Ann Heslin, Nilanjana Chatterjee, Shriya Perati, Shruti Menon, Tan A. Nguyen, Jayanta Debnath, Alejandro D. Ramirez, Xiaoyu Shi, Bin Yang, Siyu Feng, Suraj Makhija, Bo Huang, Trever G. Bivona (Source: Cell)
Source: Cell - April 14, 2021 Category: Cytology Source Type: research
The long-term genetic stability and individual specificity of the human gut microbiome
Publication date: Available online 9 April 2021Source: CellAuthor(s): Lianmin Chen, Daoming Wang, Sanzhima Garmaeva, Alexander Kurilshikov, Arnau Vich Vila, Ranko Gacesa, Trishla Sinha, Lifelines Cohort Study, Eran Segal, Rinse K. Weersma, Cisca Wijmenga, Alexandra Zhernakova, Jingyuan Fu (Source: Cell)
Source: Cell - April 10, 2021 Category: Cytology Source Type: research
Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing
Publication date: Available online 9 April 2021Source: CellAuthor(s): James K. Nuñez, Jin Chen, Greg C. Pommier, J. Zachery Cogan, Joseph M. Replogle, Carmen Adriaens, Gokul N. Ramadoss, Quanming Shi, King L. Hung, Avi J. Samelson, Angela N. Pogson, James Y.S. Kim, Amanda Chung, Manuel D. Leonetti, Howard Y. Chang, Martin Kampmann, Bradley E. Bernstein, Volker Hovestadt, Luke A. Gilbert, Jonathan S. Weissman (Source: Cell)
Source: Cell - April 10, 2021 Category: Cytology Source Type: research
TOP1 inhibition therapy protects against SARS-CoV-2-induced lethal inflammation
Publication date: Available online 30 March 2021Source: CellAuthor(s): Jessica Sook Yuin Ho, Bobo Wing-Yee Mok, Laura Campisi, Tristan Jordan, Soner Yildiz, Sreeja Parameswaran, Joseph A. Wayman, Natasha N. Gaudreault, David A. Meekins, Sabarish V. Indran, Igor Morozov, Jessie D. Trujillo, Yesai S. Fstkchyan, Raveen Rathnasinghe, Zeyu Zhu, Simin Zheng, Nan Zhao, Kris White, Helen Ray-Jones, Valeriya Malysheva (Source: Cell)
Source: Cell - April 10, 2021 Category: Cytology Source Type: research
Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes
Publication date: Available online 7 April 2021Source: CellAuthor(s): Stefan C. Dentro, Ignaty Leshchiner, Kerstin Haase, Maxime Tarabichi, Jeff Wintersinger, Amit G. Deshwar, Kaixian Yu, Yulia Rubanova, Geoff Macintyre, Jonas Demeulemeester, Ignacio Vázquez-García, Kortine Kleinheinz, Dimitri G. Livitz, Salem Malikic, Nilgun Donmez, Subhajit Sengupta, Pavana Anur, Clemency Jolly, Marek Cmero, Daniel Rosebrock (Source: Cell)
Source: Cell - April 8, 2021 Category: Cytology Source Type: research
Bioelectric signaling: Reprogrammable circuits underlying embryogenesis, regeneration, and cancer
Publication date: Available online 6 April 2021Source: CellAuthor(s): Michael Levin (Source: Cell)
Source: Cell - April 7, 2021 Category: Cytology Source Type: research
