Association of ultrasonographic parameters with subclinical white-matter hyperintensities in hypertensive patients.
Conclusions. Our study showed that in hypertensive individuals with brain SVD the extent of structural changes in cerebral microcirculation as reflected by WMHs burden is associated with the following ultrasound parameters of cerebral macrocirculation: CCA diameter and MCA-PI. PMID: 23056917 [PubMed] (Source: Cardiovascular Psychiatry and Neurology)
Source: Cardiovascular Psychiatry and Neurology - November 25, 2014 Category: Psychiatry Tags: Cardiovasc Psychiatry Neurol Source Type: research

Takotsubo or stress cardiomyopathy.
Authors: Bounhoure JP Abstract Many case reports have been published of reversible left ventricular dysfunction precipitated by sudden emotional stress. We have evaluated 10 women hospitalized for acute chest pain and dyspnea, mimicking an acute coronary syndrome, after a severe emotional trigger. Those patients, postmenopausal women, presented ST segment alterations on the EKG, minor elevations of cardiac enzymes, and biomarkers levels. At the coronarography there was not coronary thrombosis or severe stenosis, but the ventriculography showed wall motion abnormalities involving the left ventricular apex a...
Source: Cardiovascular Psychiatry and Neurology - November 25, 2014 Category: Psychiatry Tags: Cardiovasc Psychiatry Neurol Source Type: research

Smoking cessation intervention in a cardiovascular hospital based clinical setting.
Conclusions. A hospital-based smoking cessation clinic is a beneficial intervention to bring about smoking reduction in approximately half of the patients. PMID: 23097692 [PubMed] (Source: Cardiovascular Psychiatry and Neurology)
Source: Cardiovascular Psychiatry and Neurology - November 25, 2014 Category: Psychiatry Tags: Cardiovasc Psychiatry Neurol Source Type: research

Cardiac Responses during Picture Viewing in Young Male Patients with Schizophrenia.
Authors: Hempel RJ, Thayer JF, Röder CH, van Steenis HG, van Beveren NJ, Tulen JH Abstract Previous research investigating the emotion recognition ability in patients with schizophrenia has mainly focused on the recognition of facial expressions. To broaden our understanding of emotional processes in patients with schizophrenia, this study aimed to investigate whether these patients experience and process other emotionally evocative stimuli differently from healthy participants. To investigate this, we measured the cardiac and subjective responses of 33 male patients (9 with and 24 without antipsychotic m...
Source: Cardiovascular Psychiatry and Neurology - November 25, 2014 Category: Psychiatry Tags: Cardiovasc Psychiatry Neurol Source Type: research

Are cardiovascular risk factors associated with verbal learning and memory impairment in patients with schizophrenia? A cross-sectional study.
Conclusion. Our findings suggest that MetS and alcohol use may be linked with memory impairment in schizophrenia. These findings provide important insights into the interdependencies of cardiovascular risk factors and cognitive disorders and support novel strategies for treating and preventing cognitive disorders in patients with schizophrenia. PMID: 23227310 [PubMed] (Source: Cardiovascular Psychiatry and Neurology)
Source: Cardiovascular Psychiatry and Neurology - November 25, 2014 Category: Psychiatry Tags: Cardiovasc Psychiatry Neurol Source Type: research

Cardiovascular risk factors promote brain hypoperfusion leading to cognitive decline and dementia.
Authors: de la Torre JC Abstract Heart disease is the major leading cause of death and disability in the world. Mainly affecting the elderly population, heart disease and its main outcome, cardiovascular disease, have become an important risk factor in the development of cognitive decline and Alzheimer's disease (AD). This paper examines the evidence linking chronic brain hypoperfusion induced by a variety of cardiovascular deficits in the development of cognitive impairment preceding AD. The evidence indicates a strong association between AD and cardiovascular risk factors, including ApoE(4), atrial fibri...
Source: Cardiovascular Psychiatry and Neurology - November 25, 2014 Category: Psychiatry Tags: Cardiovasc Psychiatry Neurol Source Type: research

Higher cortisol predicts less improvement in verbal memory performance after cardiac rehabilitation in patients with coronary artery disease.
Conclusion. Prolonged hypothalamic pituitary adrenal axis activation may interfere with exercise-related improvements in memory in CAD. PMID: 23401745 [PubMed] (Source: Cardiovascular Psychiatry and Neurology)
Source: Cardiovascular Psychiatry and Neurology - November 25, 2014 Category: Psychiatry Tags: Cardiovasc Psychiatry Neurol Source Type: research

Multiple sclerosis and the blood-central nervous system barrier.
Authors: Palmer AM Abstract The central nervous system (CNS) is isolated from the blood system by a physical barrier that contains efflux transporters and catabolic enzymes. This blood-CNS barrier (BCNSB) plays a pivotal role in the pathophysiology of multiple sclerosis (MS). It binds and anchors activated leukocytes to permit their movement across the BCNSB and into the CNS. Once there, these immune cells target particular self-epitopes and initiate a cascade of neuroinflammation, which leads to the breakdown of the BCNSB and the formation of perivascular plaques, one of the hallmarks of MS. Immunomodulat...
Source: Cardiovascular Psychiatry and Neurology - November 25, 2014 Category: Psychiatry Tags: Cardiovasc Psychiatry Neurol Source Type: research

Apathy and cognitive test performance in patients undergoing cardiac testing.
Conclusion. Findings revealed that apathy was not prevalent in this sample though associated with medical variables. Apathy was largely unrelated to cognitive function. This pattern may be a result of the mild levels of cardiovascular disease and cognitive dysfunction in the current sample. Future studies in samples with severe cardiovascular disease or neuropsychological impairment may provide insight into these associations. PMID: 23401747 [PubMed] (Source: Cardiovascular Psychiatry and Neurology)
Source: Cardiovascular Psychiatry and Neurology - November 25, 2014 Category: Psychiatry Tags: Cardiovasc Psychiatry Neurol Source Type: research

Adult medication-free schizophrenic patients exhibit long-chain omega-3 Fatty Acid deficiency: implications for cardiovascular disease risk.
Authors: McNamara RK, Jandacek R, Rider T, Tso P, Dwivedi Y, Pandey GN Abstract Deficiency in long-chain omega-3 (LCn - 3) fatty acids, eicosapentaenoic acid (EPA, 20:5n - 3) and docosahexaenoic acid (DHA, 22:6n - 3), has been implicated in the pathoetiology of cardiovascular disease, a primary cause of excess premature mortality in patients with schizophrenia (SZ). In the present study, we determined erythrocyte EPA + DHA levels in adult medication-free patients SZ (n = 20) and age-matched healthy controls (n = 24). Erythrocyte EPA + DHA composition exhibited by SZ patients (3.5%) was significantly lower ...
Source: Cardiovascular Psychiatry and Neurology - November 25, 2014 Category: Psychiatry Tags: Cardiovasc Psychiatry Neurol Source Type: research

Depression and cardiac disease: epidemiology, mechanisms, and diagnosis.
Authors: Huffman JC, Celano CM, Beach SR, Motiwala SR, Januzzi JL Abstract In patients with cardiovascular disease (CVD), depression is common, persistent, and associated with worse health-related quality of life, recurrent cardiac events, and mortality. Both physiological and behavioral factors-including endothelial dysfunction, platelet abnormalities, inflammation, autonomic nervous system dysfunction, and reduced engagement in health-promoting activities-may link depression with adverse cardiac outcomes. Because of the potential impact of depression on quality of life and cardiac outcomes, the American ...
Source: Cardiovascular Psychiatry and Neurology - November 25, 2014 Category: Psychiatry Tags: Cardiovasc Psychiatry Neurol Source Type: research

A systematic review of depression and anxiety in patients with atrial fibrillation: the mind-heart link.
Authors: Patel D, Mc Conkey ND, Sohaney R, Mc Neil A, Jedrzejczyk A, Armaganijan L Abstract Atrial fibrillation (AF) is the most commonly seen arrhythmia in clinical practice. At present, few studies have been conducted centering on depression and anxiety in AF patients. Our aim in this systematic review is to use the relevant literature to (1) describe the prevalence of depression and anxiety in AF patients, (2) assess the impact that depression and anxiety have on illness perception in patients with AF, (3) provide evidence to support a hypothetical connection between the pathophysiology of AF and depres...
Source: Cardiovascular Psychiatry and Neurology - November 25, 2014 Category: Psychiatry Tags: Cardiovasc Psychiatry Neurol Source Type: research

Elevated troponin level with negative outcome was found in ischemic stroke.
Conclusion. cTnI is a highly specific and sensitive marker of myocardial damage, and its elevation was associated with more severe neurological deficits in acute ischemic stroke. PMID: 23840941 [PubMed] (Source: Cardiovascular Psychiatry and Neurology)
Source: Cardiovascular Psychiatry and Neurology - November 25, 2014 Category: Psychiatry Tags: Cardiovasc Psychiatry Neurol Source Type: research

Obesity in american Indian and mexican american men and women: associations with blood pressure and cardiovascular autonomic control.
Authors: Criado JR, Gilder DA, Kalafut MA, Ehlers CL Abstract Obesity is a serious public health problem, especially in some minority communities, and it has been associated with an increased risk of cardiovascular diseases. While obesity is a serious health concern in both American Indian and Mexican American populations, the relationship between obesity and cardiac autonomic control in these two populations is not well understood. The present study in a selected sample of American Indians and Mexican Americans assessed associations between obesity, blood pressure (BP), and cardiovascular autonomic contro...
Source: Cardiovascular Psychiatry and Neurology - November 25, 2014 Category: Psychiatry Tags: Cardiovasc Psychiatry Neurol Source Type: research

Sex Differences in Associations of Depressive Symptoms with Cardiovascular Risk Factors and Metabolic Syndrome among African Americans.
Authors: Cooper DC, Trivedi RB, Nelson KM, Reiber GE, Zonderman AB, Evans MK, Waldstein SR Abstract Young to middle-aged women usually have notably lower rates of cardiovascular disease (CVD) than their male counterparts, but African American women lack this advantage. Their elevated CVD may be influenced by sex differences in associations between depressed mood and CVD risk factors. This cross-sectional study examined whether relations between scores on the Center for Epidemiologic Studies-Depression (CES-D) scale and a spectrum of CVD risk factors varied by sex among African Americans (n = 1076; ages 30-...
Source: Cardiovascular Psychiatry and Neurology - November 25, 2014 Category: Psychiatry Tags: Cardiovasc Psychiatry Neurol Source Type: research