Ruth M. Pfeiffer, Mitchell H. Gail. ABSOLUTE RISK – METHODS AND APPLICATIONS IN CLINICAL MANAGEMENT AND PUBLIC HEALTH.Boca Raton, FL: Chapman & Hall/CRC Press. 201 pages, ISBN 9781466561656
(Source: Biometrical Journal)
Source: Biometrical Journal - January 1, 2018 Category: Biotechnology Authors: Anika H üsing Tags: BOOK REVIEW Source Type: research

Small area estimation of proportions with different levels of auxiliary data
Abstract Binary data are often of interest in many small areas of applications. The use of standard small area estimation methods based on linear mixed models becomes problematic for such data. An empirical plug‐in predictor (EPP) under a unit‐level generalized linear mixed model with logit link function is often used for the estimation of a small area proportion. However, this EPP requires the availability of unit‐level population information for auxiliary data that may not be always accessible. As a consequence, in many practical situations, this EPP approach cannot be applied. Based on the level of auxiliary infor...
Source: Biometrical Journal - January 1, 2018 Category: Biotechnology Authors: Hukum Chandra, Sushil Kumar, Kaustav Aditya Tags: RESEARCH PAPER Source Type: research

Reconstruction of molecular network evolution from cross ‐sectional omics data
Abstract Cross‐sectional studies may shed light on the evolution of a disease like cancer through the comparison of patient traits among disease stages. This problem is especially challenging when a gene–gene interaction network needs to be reconstructed from omics data, and, in addition, the patients of each stage need not form a homogeneous group. Here, the problem is operationalized as the estimation of stage‐wise mixtures of Gaussian graphical models (GGMs) from high‐dimensional data. These mixtures are fitted by a (fused) ridge penalized EM algorithm. The fused ridge penalty shrinks GGMs of contiguous stages. ...
Source: Biometrical Journal - January 1, 2018 Category: Biotechnology Authors: Mehran Aflakparast, Mathisca C. M. de Gunst, Wessel N. van Wieringen Tags: Research Paper Source Type: research

Multiple ‐rater kappas for binary data: Models and interpretation
Biometrical Journal,Volume 60, Issue 2, Page 381-394, March 2018. (Source: Biometrical Journal)
Source: Biometrical Journal - December 27, 2017 Category: Biotechnology Source Type: research

Modeling time ‐varying exposure using inverse probability of treatment weights
Biometrical Journal,Volume 60, Issue 2, Page 323-332, March 2018. (Source: Biometrical Journal)
Source: Biometrical Journal - December 27, 2017 Category: Biotechnology Source Type: research

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Biometrical Journal,Volume 60, Issue 2, Page 381-394, March 2018. (Source: Biometrical Journal)
Source: Biometrical Journal - December 27, 2017 Category: Biotechnology Source Type: research

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Biometrical Journal,Volume 60, Issue 2, Page 323-332, March 2018. (Source: Biometrical Journal)
Source: Biometrical Journal - December 27, 2017 Category: Biotechnology Source Type: research

Modeling time ‐varying exposure using inverse probability of treatment weights
In this study, patients received one or multiple medications (thiopurines, methotrexate, and anti‐TNF) over time. We used a Cox marginal structural model to assess the effect of thiopurines exposure on the cause‐specific hazard for cancer incidence considering other treatments as confounding factors. To this end, we used our extended function which is available online in the Supporting Information. (Source: Biometrical Journal)
Source: Biometrical Journal - December 27, 2017 Category: Biotechnology Authors: Nathalie Graff éo, Aurélien Latouche, Ronald B. Geskus, Sylvie Chevret Tags: RESEARCH PAPER Source Type: research

Local influence diagnostics for hierarchical finite ‐mixture random‐effects models
Biometrical Journal,Volume 60, Issue 2, Page 369-380, March 2018. (Source: Biometrical Journal)
Source: Biometrical Journal - December 19, 2017 Category: Biotechnology Source Type: research

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Biometrical Journal,Volume 60, Issue 2, Page 369-380, March 2018. (Source: Biometrical Journal)
Source: Biometrical Journal - December 19, 2017 Category: Biotechnology Source Type: research

Ying Yuan, Hoang Q. Nguyen, and Peter F. Thall. BAYESIAN DESIGNS FOR PHASE I –II CLINICAL TRIALS. Boca Raton, FL: Chapman and Hall/CRC Biostatistics Series. 310 pages, ISBN 9781498709552
Biometrical Journal,Volume 60, Issue 2, Page 416-417, March 2018. (Source: Biometrical Journal)
Source: Biometrical Journal - December 13, 2017 Category: Biotechnology Source Type: research

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Biometrical Journal,Volume 60, Issue 2, Page 416-417, March 2018. (Source: Biometrical Journal)
Source: Biometrical Journal - December 13, 2017 Category: Biotechnology Source Type: research

Variance component analysis to assess protein quantification in biomarker discovery. Application to MALDI ‐TOF mass spectrometry
Biometrical Journal,Volume 60, Issue 2, Page 262-274, March 2018. (Source: Biometrical Journal)
Source: Biometrical Journal - December 12, 2017 Category: Biotechnology Source Type: research

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Biometrical Journal,Volume 60, Issue 2, Page 262-274, March 2018. (Source: Biometrical Journal)
Source: Biometrical Journal - December 12, 2017 Category: Biotechnology Source Type: research

Classification of early ‐stage non‐small cell lung cancer by weighing gene expression profiles with connectivity information
Biometrical Journal, EarlyView. (Source: Biometrical Journal)
Source: Biometrical Journal - December 5, 2017 Category: Biotechnology Source Type: research