Biochimica et Biophysica Acta (BBA) Proteins and Proteomics This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Corrigendum to “Capreomycin inhibits the initiation of amyloid fibrillation and suppresses amyloid induced cell toxicity” [Biochim. Biophy. Acta 1866 (2018) 549–557]
Publication date: Available online 6 March 2020Source: Biochimica et Biophysica Acta (BBA) - Proteins and ProteomicsAuthor(s): M.K. Siddiqi, P. Alam, S.K. Chaturvedi, M.V. Khan, S. Nusrat, S. Malik, R.H. Khan (Source: Biochimica et Biophysica Acta (BBA) Proteins and Proteomics)
Source: Biochimica et Biophysica Acta (BBA) Proteins and Proteomics - March 7, 2020 Category: Biochemistry Source Type: research

Corrigendum to “Structural and biochemical characterization of two heme binding sites on α1-microglobulin using site directed mutagenesis and molecular simulation” [BBAPAP 1864/1 (2016) Page 29 to 41]
Publication date: Available online 5 March 2020Source: Biochimica et Biophysica Acta (BBA) - Proteins and ProteomicsAuthor(s): Sigurbjörg Rutardottir, Elena Karnaukhova, Chanin Nantasenamat, Napat Songtawee, Virapong Prachayasittikul, Mohsen Rajabi, Lena Wester Rosenlöf, Abdu I. Alayash, Bo Åkerström (Source: Biochimica et Biophysica Acta (BBA) Proteins and Proteomics)
Source: Biochimica et Biophysica Acta (BBA) Proteins and Proteomics - March 7, 2020 Category: Biochemistry Source Type: research

Review and comparative analysis of machine learning-based phage virion protein identification methods
Publication date: Available online 2 March 2020Source: Biochimica et Biophysica Acta (BBA) - Proteins and ProteomicsAuthor(s): Chaolu Meng, Jun Zhang, Xiucai Ye, Fei Guo, Quan Zou (Source: Biochimica et Biophysica Acta (BBA) Proteins and Proteomics)
Source: Biochimica et Biophysica Acta (BBA) Proteins and Proteomics - March 3, 2020 Category: Biochemistry Source Type: research

Thermodynamics, cooperativity and stability of the tetracycline repressor (TetR) upon tetracycline binding
Publication date: Available online 27 February 2020Source: Biochimica et Biophysica Acta (BBA) - Proteins and ProteomicsAuthor(s): Gottfried Julius Palm, Ina Buchholz, Sebastiaan Werten, Britta Girbardt, Leona Berndt, Mihaela Delcea, Winfried Hinrichs (Source: Biochimica et Biophysica Acta (BBA) Proteins and Proteomics)
Source: Biochimica et Biophysica Acta (BBA) Proteins and Proteomics - February 29, 2020 Category: Biochemistry Source Type: research

Structural and mechanistic insights into the Keap1-Nrf2 system as a route to drug discovery
Publication date: Available online 28 February 2020Source: Biochimica et Biophysica Acta (BBA) - Proteins and ProteomicsAuthor(s): Sarah K. Madden, Laura S. Itzhaki (Source: Biochimica et Biophysica Acta (BBA) Proteins and Proteomics)
Source: Biochimica et Biophysica Acta (BBA) Proteins and Proteomics - February 29, 2020 Category: Biochemistry Source Type: research

Editorial Board
Publication date: May 2020Source: Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, Volume 1868, Issue 5Author(s): (Source: Biochimica et Biophysica Acta (BBA) Proteins and Proteomics)
Source: Biochimica et Biophysica Acta (BBA) Proteins and Proteomics - February 22, 2020 Category: Biochemistry Source Type: research

Conformational analysis of the riboflavin-responsive ETF:QO-p.Pro456Leu variant associated with mild multiple acyl-CoA dehydrogenase deficiency
Publication date: Available online 19 February 2020Source: Biochimica et Biophysica Acta (BBA) - Proteins and ProteomicsAuthor(s): Tânia G. Lucas, Bárbara J. Henriques, Cláudio M. GomesAbstractMultiple-CoA dehydrogenase deficiency (MADD) is an inborn disorder of fatty acid and amino acid metabolism caused by mutations in the genes encoding for human electron transfer flavoprotein (ETF) and its partner electron transfer flavoprotein:ubiquinone oxidoreductase (ETF:QO). Albeit a rare disease, extensive newborn screening programs contributed to a wider coverage of MADD genotypes. However, the impact of non-lethal mutations ...
Source: Biochimica et Biophysica Acta (BBA) Proteins and Proteomics - February 20, 2020 Category: Biochemistry Source Type: research

Combinatorial degradomics: Precision tools to unveil proteolytic processes in biological systems
Publication date: Available online 20 February 2020Source: Biochimica et Biophysica Acta (BBA) - Proteins and ProteomicsAuthor(s): Simonas Savickas, Philipp Kastl, Ulrich auf dem KellerAbstractThe biological activity of a protein is regulated at many levels ranging from control of transcription and translation to post-translational modifications (PTM). Proteolytic processing is an irreversible PTM generating novel isoforms of a mature protein termed proteoforms. Proteoform dynamics is a major focus of current proteome research, since it has been associated with many pathological conditions. Mass-spectrometry (MS)-based pro...
Source: Biochimica et Biophysica Acta (BBA) Proteins and Proteomics - February 20, 2020 Category: Biochemistry Source Type: research

Cone snail analogs of the pituitary hormones oxytocin/vasopressin and their carrier protein neurophysin. Proteomic and transcriptomic identification of conopressins and conophysins
Publication date: Available online 10 February 2020Source: Biochimica et Biophysica Acta (BBA) - Proteins and ProteomicsAuthor(s): Sanjeev Kumar, M. Vijayasarathy, M.A. Venkatesha, P. Sunita, P. BalaramAbstractTranscriptomic analysis of cone snail venom duct tissue has permitted the identification of diverse conopressin/conophysin precursor sequences from seven distinct conus species. Multiple precursor isoforms are present in C.monile, C.lividus and C.loroisii. Aqueous extracts of the venom duct tissue from C.monile yield a band, at ~ 15-20 kDa on SDS-PAGE. In-gel trypsin digestion, followed by mass spectrometry establi...
Source: Biochimica et Biophysica Acta (BBA) Proteins and Proteomics - February 11, 2020 Category: Biochemistry Source Type: research

Editorial Board
Publication date: April 2020Source: Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, Volume 1868, Issue 4Author(s): (Source: Biochimica et Biophysica Acta (BBA) Proteins and Proteomics)
Source: Biochimica et Biophysica Acta (BBA) Proteins and Proteomics - February 6, 2020 Category: Biochemistry Source Type: research

Production, thermodynamic characterization, and fruit juice quality improvement characteristics of an Exo-polygalacturonase from Penicillium janczewskii
In conclusion, the catalytic activity, thermal steadiness, and fruit juices clarification performance of Exo-PG manifests a great prospect for bio-industrial exploitation. (Source: Biochimica et Biophysica Acta (BBA) Proteins and Proteomics)
Source: Biochimica et Biophysica Acta (BBA) Proteins and Proteomics - February 5, 2020 Category: Biochemistry Source Type: research

Targeted inhibition of Amyloidogenesis using a non-toxic, serum stable strategically designed cyclic peptide with therapeutic implications
Publication date: Available online 4 February 2020Source: Biochimica et Biophysica Acta (BBA) - Proteins and ProteomicsAuthor(s): Ranit Pariary, Baijayanti Ghosh, Zuzana Bednarikova, Kyriakos Gabriel Varnava, Bhisma N. Ratha, Sreyan Raha, Dipita Bhattacharyya, Zuzana Gazova, Vijayalekshmi Sarojini, Atin K. Mandal, Anirban BhuniaAbstractAmyloidogenic disorders are currently rising as a global health issue, prompting more and more studies dedicated to the development of effective targeted therapeutics. The innate affinity of these amyloidogenic proteins towards the biomembranes adds further complexities to the systems. Our p...
Source: Biochimica et Biophysica Acta (BBA) Proteins and Proteomics - February 5, 2020 Category: Biochemistry Source Type: research

N-succinylamino acid racemases: Enzymatic properties and biotechnological applications
Publication date: Available online 23 January 2020Source: Biochimica et Biophysica Acta (BBA) - Proteins and ProteomicsAuthor(s): Sergio Martínez-Rodríguez, Pablo Soriano-Maldonado, Jose Antonio GaviraAbstractThe N-succinylamino acid racemase/o-succinylbenzoate synthase (NSAR/OSBS) subfamily from the enolase superfamily contains different enzymes showing promiscuous N-substituted-amino acid racemase (NxAR) activity. These enzymes were originally named as N-acylamino acid racemases because of their industrial application. Nonetheless, they are pivotal in several enzymatic cascades due to their versatility to catalyze a wi...
Source: Biochimica et Biophysica Acta (BBA) Proteins and Proteomics - January 24, 2020 Category: Biochemistry Source Type: research

Kinetics aspects of Gamma-hydroxybutyrate dehydrogenase
Publication date: Available online 22 January 2020Source: Biochimica et Biophysica Acta (BBA) - Proteins and ProteomicsAuthor(s): Esther S. Taxon, Lila P. Halbers, Stanley M. ParsonsAbstractTwo groups of metabolically related enzymes, the Group III family of Fe2+-dependent alcohol dehydrogenases (ADHs) and the separate subfamily of nucleoside diphosphates linked to x (nudix) hydrolases that activate Group III ADHs are under-characterized. Here we report the steady-state initial-velocity forward direction (alcohol → aldehyde) reaction of a Group III ADH, namely gamma-hydroxybutyrate dehydrogenase (GHBDH, UniProt: Q59104),...
Source: Biochimica et Biophysica Acta (BBA) Proteins and Proteomics - January 23, 2020 Category: Biochemistry Source Type: research

Standard Gibbs energy of metabolic reactions: V. enolase reaction
Publication date: Available online 18 January 2020Source: Biochimica et Biophysica Acta (BBA) - Proteins and ProteomicsAuthor(s): Thorsten Greinert, Kristina Vogel, Astrid-Ina Seifert, Riko Siewert, Irina V. Andreeva, Sergey P. Verevkin, Thomas Maskow, Gabriele Sadowski, Christoph HeldAbstractThe glycolytic pathway is one of the most important pathways for living organisms, due to its role in energy production and as supplier of precursors for biosynthesis in living cells. This work focuses on determination of the standard Gibbs energy of reaction ΔRg′0 of the enolase reaction, the ninth reaction in the glycolysis pathw...
Source: Biochimica et Biophysica Acta (BBA) Proteins and Proteomics - January 18, 2020 Category: Biochemistry Source Type: research