Human papilloma virus detection in oropharyngeal cancer with gargle samples.
CONCLUSIONS: use of the gargling method to determine HPV positivity in OPSCC patients appears feasible, except in patients with very small tumours. Real-time polymerase chain reaction using gargle samples may have greater clinical efficacy than the swabbing method.
PMID: 29709129 [PubMed - in process] (Source: B-ENT)
Source: B-ENT - May 3, 2018 Category: ENT & OMF Tags: B-ENT Source Type: research
Induction chemotherapy followed by supracricoid partial laryngectomy (SCPL) with cricohyoidoepiglottopexy (CHEP) in T3NO arytenoid fixation-related glottic cancer.
CONCLUSION: Neoadjuvant chemotherapy proved beneficial in patients waiting for surgery, helped maximize the oncologic benefit of the surgery provided (good local control using SCPL with CHEP), improved regional and distant control, minimized side effects by avoiding treatment with radiotherapy whenever possible, and proved feasible even in the presence of ipsilateral arytenoid fixation. Our results are encouraging, although a multi-centre randomized clinical trial should be performed in order to identify the true impact of this approach.
PMID: 29709130 [PubMed - in process] (Source: B-ENT)
Source: B-ENT - May 3, 2018 Category: ENT & OMF Tags: B-ENT Source Type: research
Airway intervention in cases of acute epiglottitis.
CONCLUSIONS: When considering whether airway intervention should be performed in cases of acute epiglottitis, the most important clinical factor is the laryngoscopic finding that "less than 50% of the glottis area being visible." Other important clinical factors to consider are odynophagia, drooling, hoarseness, muffled voice, dyspnoea, swelling of the posterior side of the epiglottis and a high WBC count.
PMID: 29709131 [PubMed - in process] (Source: B-ENT)
Source: B-ENT - May 3, 2018 Category: ENT & OMF Tags: B-ENT Source Type: research
Comparison of the cough reflex test and water swallowing test in healthy participants and neurological patients.
CONCLUSION: The CRT correlated significantly with the WST. Unlike the WST, the CRT could be easily administered to severely impaired patients. Our results indicate the use of the CRT as a screening test for silent aspirators.
PMID: 29709132 [PubMed - in process] (Source: B-ENT)
Source: B-ENT - May 3, 2018 Category: ENT & OMF Tags: B-ENT Source Type: research
Assessment and management of presumed branchial cleft cysts: our experience.
CONCLUSIONS: Patients >40 years with or without multiple lymph nod 'es on imaging should be treated as presumed meta- static cancer. Consideration should be given to concurrent panendoscopy and intra-operative frozen section +/- selective neck dissection after discussion at the Head & Neck MDT.
PMID: 29709133 [PubMed - in process] (Source: B-ENT)
Source: B-ENT - May 3, 2018 Category: ENT & OMF Tags: B-ENT Source Type: research
The microbiology of normal non-inflamed sinuses.
CONCLUSIONS: Healthy non-inflamed sinuses are colonized by rich and diverse populations of aerobic and anaerobic bacterial flora. These organisms may participate in sinus inflammation if the right circumstances arise. The host response or lack of response to the normal sinus flora may be central to the development of sinus inflammation. Corynebacterium tuberculostearicum seems to have a potential pathogenic role, while certain probiotics may have a protective effect. Modulation of the sinus flora by topical antimicrobial and/or probiotic organisms which may interfere with the growth of potential bacterial and fungal pathog...
Source: B-ENT - May 3, 2018 Category: ENT & OMF Tags: B-ENT Source Type: research
Periostin: a novel biomarker for chronic rhinosinusitis.
CONCLUSION: Periostin can be used as a novel biomarker for chronic rhinosinusitis, which provides a potential target for individualized therapy of chronic rhinosinusitis.
PMID: 29709135 [PubMed - in process] (Source: B-ENT)
Source: B-ENT - May 3, 2018 Category: ENT & OMF Tags: B-ENT Source Type: research
Corticosteroid hypersensitivity in allergic rhinitis.
CONCLUSION: our study is the largest to date investigating CH in patients with allergic rhinitis and patients with allergic rhinitis have been found to have a high incidence (14%) of corticosteroid hypersensitivity, which may affect the response of patients to intranasal corticosteroid treatment.
PMID: 29709136 [PubMed - in process] (Source: B-ENT)
Source: B-ENT - May 3, 2018 Category: ENT & OMF Tags: B-ENT Source Type: research
Smell functions in patients with multiple sclerosis: a prospective case-control study.
CONCLUSION: There is a deterioration in the smell functions of patients with MS. Therefore, we highly recommend that ENT specialists use the easily accessible and reliable BSIT for the diagnosis of smell disorders.
PMID: 29709137 [PubMed - in process] (Source: B-ENT)
Source: B-ENT - May 3, 2018 Category: ENT & OMF Tags: B-ENT Source Type: research
Isolated laryngeal leishmaniasis in an immunocompetent patient: a case report.
CONCLUSIONS: This clinical case highlights the need to consider isolated laryngeal Leishmaniasis in the differential diagnoses of laryngeal tumour lesions, even in immunocompetent subjects who live in endemic zones, in order to ensure an early and correct therapeutic approach.
PMID: 29709138 [PubMed - in process] (Source: B-ENT)
Source: B-ENT - May 3, 2018 Category: ENT & OMF Tags: B-ENT Source Type: research
Radiation-induced carcinosarcoma of the submandibular gland: case report and review of literature.
We present the case of a 60-year-old man diagnosed with a T2N2cM0 squamous cell carcinoma at the right base of the tongue (BOT). The patient was treated with neoadjuvant chemotherapy and 3D-conformal radiotherapy (3D-CRT) to the BOT and bilateral neck. He developed left submandibular firmness five years after treatment, initially diagnosed as radiation-induced fibrosis. The increasing size of the left submandibular mass two years later prompted further imaging, which showed a 2.2x1.8 cm mass in the left submandibular region in the previously irradiated field. This was diagnosed as a radiation-induced submandibular gland ma...
Source: B-ENT - May 3, 2018 Category: ENT & OMF Tags: B-ENT Source Type: research
Surgical treatments for snoring.
CONCLUSIONS: All surgical treatments effectively and persistently reduced snoring and sleepiness symptom scores. The highest rates of success were observed with osteotomies and UPPP/FEP procedures.
PMID: 29557556 [PubMed - in process] (Source: B-ENT)
Source: B-ENT - March 24, 2018 Category: ENT & OMF Tags: B-ENT Source Type: research
Effects of Smoking on healthy oral mucosa: a red-green-blue (photographic) evaluation.
CONCLUSION: The study revealed that the normal oral mucosae of the smokers were clearly darker than the non-smokers'. This finding is significant because dark mucosa is thought to be the precursor to any premalignant lesions.
PMID: 29557557 [PubMed - in process] (Source: B-ENT)
Source: B-ENT - March 24, 2018 Category: ENT & OMF Tags: B-ENT Source Type: research
Transnasal endoscopic management of anterior cerebrospinal fluid (CSF) leak: experience from a large case series.
CONCLUSIONS: The endoscopic transnasal approach is a reliable technique for treating CSF leaks. The intrathecal fluorescein test is safe and helpful in locating the defect. The fascia lata proved the best graft available in our experience.
PMID: 29557558 [PubMed - in process] (Source: B-ENT)
Source: B-ENT - March 24, 2018 Category: ENT & OMF Tags: B-ENT Source Type: research
Felix tympanoplasty: functional results of a single surgeon's technique in the scope of a literature review on influencing factors.
Authors: Castelli ML, Evangelista A
Abstract
Felix tympanoplasty: functional results of a single surgeon's technique in the scope of a literature review on influencing factors.
OBJECTIVE: The outcome of myringoplasties may be affected by local, general or epidemiologic factors. We reduced the variability of the surgical procedure to a minimum, in order to better evaluate the role of these factors on the functional results. To accomplish this, a single surgical procedure performed by a single surgeon was analysed in this retrospective study. The analysis was performed on a cohort study of patients w...
Source: B-ENT - March 24, 2018 Category: ENT & OMF Tags: B-ENT Source Type: research
