The Promise and Potential Perils of Big Data for Advancing Symptom Management Research in Populations at Risk for Health Disparities.
Authors: Bakken S, Reame N Abstract Symptom management research is a core area of nursing science and one of the priorities for the National Institute of Nursing Research, which specifically focuses on understanding the biological and behavioral aspects of symptoms such as pain and fatigue, with the goal of developing new knowledge and new strategies for improving patient health and quality of life. The types and volume of data related to the symptom experience, symptom management strategies, and outcomes are increasingly accessible for research. Traditional data streams are now complemented by consumer-ge...
Source: Annual review of nursing research - December 19, 2015 Category: Nursing Tags: Annu Rev Nurs Res Source Type: research

Index.
Authors: PMID: 26673386 [PubMed - in process] (Source: Annual review of nursing research)
Source: Annual review of nursing research - December 19, 2015 Category: Nursing Tags: Annu Rev Nurs Res Source Type: research

Chapter 1 Common Data Elements and Federal Interagency Traumatic Brain Injury Research Informatics System for TBI Research.
Authors: Thompson HJ, Vavilala MS, Rivara FP Abstract Despite increased attention to traumatic brain injury (TBI), there remains no specific treatment and available interventions focus rather on the prevention of secondary injury. One of the reasons posited for the lack of a successful therapy is the amalgamation of various types of injuries under the same severity category in clinical trials. Informatics approaches have been suggested as a means to develop an improved classification system for TBI. As a result of federal interagency efforts, common data elements (CDEs) for TBI have now been developed. Fur...
Source: Annual review of nursing research - June 4, 2015 Category: Nursing Tags: Annu Rev Nurs Res Source Type: research

Chapter 2 traumatic brain injury research in military populations.
Authors: Kasper CE Abstract Traumatic brain injury (TBI) in all of its forms-blast, concussive, and penetrating-has been an unfortunate sequela of warfare since ancient times. The continued evolution of military munitions and armor on the battlefield, as well as the insurgent use of improvised explosive devices, has led to blast-related TBI whose long-term effects on behavior and cognition are not yet known. Advances in medical care have greatly increased survival from these types of injuries. Therefore, an understanding of the potential health effects of TBI is essential. This review focuses on specific a...
Source: Annual review of nursing research - June 4, 2015 Category: Nursing Tags: Annu Rev Nurs Res Source Type: research

Chapter 3 animal models of traumatic brain injury: is there an optimal model that parallels human brain injury?
Authors: Briones TL Abstract Traumatic brain injury (TBI) is the leading cause of mortality and morbidity in the younger population worldwide. Survivors of TBI often experience long-term disability in the form of cognitive, sensorimotor, and affective impairments. Despite the high prevalence in, and cost of TBI to, both individuals and society, some of its underlying pathophysiology is not completely understood. Animal models have been developed over the past few decades to closely replicate the different facets of TBI in humans to better understand the underlying pathophysiology and behavioral impairments...
Source: Annual review of nursing research - June 4, 2015 Category: Nursing Tags: Annu Rev Nurs Res Source Type: research

Chapter 4 genomics, transcriptomics, and epigenomics in traumatic brain injury research.
Authors: Puccio AM, Alexander S Abstract The long-term effects and significant impact of the full spectrum of traumatic brain injury (TBI) has received increased attention in recent years. Despite increased research efforts, there has been little movement toward improving outcomes for the survivors of TBI. TBI is a heterogeneous condition with a complex biological response, and significant variability in human recovery contributes to the difficulty in identifying therapeutics that improve outcomes. Personalized medicine, identifying the best course of treatment for a given individual based on individual ch...
Source: Annual review of nursing research - June 4, 2015 Category: Nursing Tags: Annu Rev Nurs Res Source Type: research

Chapter 5 cerebral perfusion pressure and intracranial pressure in traumatic brain injury.
Authors: Mitchell PH, Kirkness C, Blissitt PA Abstract Nearly 300,000 children and adults are hospitalized annually with traumatic brain injury (TBI) and monitored for many vital signs, including intracranial pressure (ICP) and cerebral perfusion pressure (CPP). Nurses use these monitored values to infer the risk of secondary brain injury. The purpose of this chapter is to review nursing research on the monitoring of ICP and CPP in TBI. In this context, nursing research is defined as the research conducted by nurse investigators or research about the variables ICP and CPP that pertains to the nursing care ...
Source: Annual review of nursing research - June 4, 2015 Category: Nursing Tags: Annu Rev Nurs Res Source Type: research

Chapter 6 state of the science of pediatric traumatic brain injury: biomarkers and gene association studies.
CONCLUSION: Biomarker and gene attributes are grossly understudied in pediatric TBI in comparison to adults. Although recent advances recognize the importance of biomarkers in the study of brain injury, the limited number of studies and genomic associations in the injured brain has shown the need for common data elements, larger sample sizes, heterogeneity, and common collection methods that allow for greater understanding of the injured pediatric brain. By building on to the consortium of interprofessional scientists, continued research priorities would lead to improved outcome prediction and treatment strategies for chil...
Source: Annual review of nursing research - June 4, 2015 Category: Nursing Tags: Annu Rev Nurs Res Source Type: research

Chapter 7 the relationship between coping and psychological adjustment in family caregivers of individuals with traumatic brain injury: a systematic review.
Authors: Anderson MI, Simpson GK, Daher M, Matheson L Abstract A systematic review was conducted to evaluate the association between coping (as measured by the Ways of Coping Questionnaire [WOCQ]) and psychological adjustment in caregivers of individuals with traumatic brain injury (TBI). A search conducted using the CINAHL, Medline, and PsycINFO databases yielded 201 citations between 1974 and 2014. A total of seven articles met the inclusion criteria; namely, the respondents who completed the WOCQ were family caregivers of individuals with TBI (including 66-item, 42-item, or 21-item versions). Reviews we...
Source: Annual review of nursing research - June 4, 2015 Category: Nursing Tags: Annu Rev Nurs Res Source Type: research

Chapter 8 Military Personnel With Traumatic Brain Injuries and Insomnia Have Reductions in PTSD and Improved Perceived Health Following Sleep Restoration: A Relationship Moderated by Inflammation.
CONCLUSIONS: Military personnel with TBIs who have a reduction in insomnia symptoms following a standard-of-care treatment report less severe symptoms of depression and PTSD and improved HRQOL, which relate to decreased plasma concentrations of CRP. These findings suggest that treatment for sleep disturbances in this TBI + military population is associated with improvements in health and decreases in inflammation. The contributions of inflammation-induced changes in PTSD and depression in sleep disturbances in TBI + military personnel require further study. PMID: 25946388 [PubMed - in process] (Source: Annual revie...
Source: Annual review of nursing research - June 4, 2015 Category: Nursing Tags: Annu Rev Nurs Res Source Type: research

Index.
Authors: PMID: 25946389 [PubMed - in process] (Source: Annual review of nursing research)
Source: Annual review of nursing research - June 4, 2015 Category: Nursing Tags: Annu Rev Nurs Res Source Type: research