Acute gonadotropin response to the gonadotropin releasing hormone agonist (decapeptyl) in girls with pubertal pathology
Abstract The aim of the study was to assess the effect of a single injection of the GnRH agonist decapeptyl on gonadotropin secretion in girls with different pubertal disorders. The test was performed in two groups of girls with premature thelarche (younger and older than 2 years of age), girls with premature adrenarche and postmenarcheal girls with policystic ovaries. The GnRH agonist decapeptyl stimulated gonadotropins secretion in pre- and postmenarcheal girls. The responsiveness of LH was increased significantly in puberty. FSH response was exaggerated in the girls with premature thelarche before th...
Source: Annals of Diagnostic Paediatric Pathology - March 1, 1998 Category: Pathology Source Type: research