Relationship between nuclear DNA fragmentation, mitochondrial DNA damage and standard sperm parameters in spermatozoa of fertile and sub ‐fertile men before and after freeze‐thawing procedure
In conclusion, freeze‐thawing process affects not only semen parameters but also n‐DNA and mt‐DNA. Therefore, n‐DNA and mt‐DNA could be used as sensitive parameters for assessment of the cryodamage of human spermatozoa. (Source: Andrologia)
Source: Andrologia - March 12, 2018 Category: Urology & Nephrology Authors: H. Amor, A. Zeyad, Y. Alkhaled, M. Laqqan, A. Saad, H. Ben Ali, M. E. Hammadeh Tags: ORIGINAL ARTICLE Source Type: research
Efficacy and safety of daily use of tadalafil in treatment of patients with premature ejaculation: A randomised placebo‐controlled clinical trial
This study showed that there were no statistically significant differences between patients in the placebo and tadalafil groups regarding the mean values of the seven questions and total scores of the AIPE questionnaire before treatment (p value >.05). The mean values of the seven questions and total scores of AIPE questionnaire in the tadalafil group were significantly higher than the placebo group after treatment (p value = .001). This study concluded that once‐daily use of 5 mg tadalafil for 6 weeks was effective and well tolerated in the treatment of patients with PE. (Source: Andrologia)
Source: Andrologia - March 12, 2018 Category: Urology & Nephrology Authors: M. Abu El ‐Hamd Tags: ORIGINAL ARTICLE Source Type: research
Is there any correlation between sperm parameters and chromatin quality with embryo morphokinetics in patients with male infertility?
Summary
The main goal was to evaluate the correlation between sperm parameters and chromatin quality with embryo kinetics via time‐lapse monitoring system (TLM). A total of 40 couples involved in the ICSI program as a result of male infertility. For assessment of sperm chromatin and DNA quality, we used aniline blue, toluidine blue, chromomycin A3, acridine orange and terminal transferase‐mediated deoxyuridine triphosphate biotin end labelling assays. All mature oocytes were injected, and the generated zygotes (2PNs) were cultured in TLM. In day 3 after injection, single embryo transfer (SET) was carried out according ...
Source: Andrologia - March 12, 2018 Category: Urology & Nephrology Authors: E. Mangoli, M. A. Khalili, A. R. Talebi, S. Ghasemi ‐Esmailabad, A. Hosseini Tags: ORIGINAL ARTICLE Source Type: research
Grape seed extract attenuates dexamethasone ‐induced testicular and thyroid dysfunction in male albino rats
This study scrutinised the ameliorative properties of grape seed extract (GSE) in dexamethasone (DEX)‐induced testicular and thyroid dysfunction associated with oxidative stress in male albino rats. Thirty‐two healthy adult male albino rats were divided into four groups of eight animals each: normal, DEX control, DEX + GSE (200 mg/kg body weight) group and DEX + GSE (400 mg/kg body weight) group. The body weight gain and testes weight were assessed. Plasma testosterone and thyroid profile were determined. Testicular glucose‐6‐phosphate dehydrogenase (G‐6‐PDH), acid phosphatase (ACP), total protein and glu...
Source: Andrologia - March 12, 2018 Category: Urology & Nephrology Authors: N. A. Hasona Tags: ORIGINAL ARTICLE Source Type: research
Clinical aspects of 49 infertile males with 45,X/46,XY mosaicism karyotype: A case series
Summary
Disorders of sex development (DSD) are congenital abnormalities as an atypical development process in either gonadal or chromosomal structure. It is the cause of the abnormality in phenotype and characteristics. Chromosomal analysis plays an important role in the DSD determination. 45,X/46,XY mosaicism is a rare karyotype, and its prevalence is about 1.5 in 10,000 newborns. It affects the growth, hormonal balance, gonad development and histology. All data such as height, male general appearance, testis size and volume, external genitalia, spermogram and hormonal levels, testis pathology, Y chromosome microdeletion ...
Source: Andrologia - March 12, 2018 Category: Urology & Nephrology Authors: F. Mohammadpour Lashkari, M. A. Sadighi Gilani, A. Ghaheri, M. R. Zamanian, P. Borjian Boroujeni, A. Mohseni Meybodi, M. Sabbaghian Tags: CASE REPORT Source Type: research
Protective potential of royal jelly against cadmium ‐induced infertility in male rats
This study aimed to investigate the protective potential of Royal jelly (RJ) against cadmium (Cd)‐induced testicular dysfunction in rats. Thirty‐five adult male Wistar rats were assigned into five groups. G I; (control) injected intraperitoneally with saline, G II injected intraperitoneally with a single dose of CdCl2 (1 mg/kg BW), G III received RJ (100 mg/kg BW/day) orally, G IV was pre‐treated with RJ for 1 week then, treated with CdCl2, and G V was co‐treated with RJ and CdCl2. After day 56, serum and tissue samples were collected and analysed. The results showed decreased serum testosterone, luteinising hor...
Source: Andrologia - March 12, 2018 Category: Urology & Nephrology Authors: Mohamed M. Ahmed, Samir A. El ‐Shazly, Mohamed E. Alkafafy, Alaa A. Mohamed, Ahmed A. Mousa Tags: ORIGINAL ARTICLE Source Type: research
Quercetin and rutin ameliorates sulphasalazine ‐induced spermiotoxicity, alterations in reproductive hormones and steroidogenic enzyme imbalance in rats
Summary
Certain dietary flavonoids exhibit protective potentials against drug‐induced male reproductive toxicities. We investigated the protective effects of quercetin and rutin on sulphasalazine‐induced alterations in steroidogenic enzyme activity, hormone profile and spermiotoxicity in rats. Sulphasalazine (SASP, 600 mg/kg bw) was administered alone or in combination with quercetin (20 mg/kg bw) or rutin (10 mg/kg bw) for 14 days. SASP treatment significantly increased relative weights of the epididymis and seminal vesicles. Also, testicular and epididymal sperm numbers (TSN, ESN), motility, daily sperm productio...
Source: Andrologia - March 7, 2018 Category: Urology & Nephrology Authors: S. O. Osawe, E. O. Farombi Tags: ORIGINAL ARTICLE Source Type: research
Quercetin and rutin ameliorates sulphasalazine ‐induced spermiotoxicity, alterations in reproductive hormones and steroidogenic enzyme imbalance in rats
Andrologia,Volume 50, Issue 5, June 2018. (Source: Andrologia)
Source: Andrologia - March 7, 2018 Category: Urology & Nephrology Authors: S. O.
Osawe
,
E. O.
Farombi Source Type: research
Semen parameters are unaffected by statin use in men evaluated for infertility
Andrologia,Volume 50, Issue 5, June 2018. (Source: Andrologia)
Source: Andrologia - March 7, 2018 Category: Urology & Nephrology Authors: S.
Keihani
,
C.
Martin
,
J. R.
Craig
,
C.
Zhang
,
A. P.
Presson
,
J. B.
Myers
,
K. I.
Aston
,
B. R.
Emery
,
D. T.
Carrell
,
J. M.
Hotaling Source Type: research
Klinefelter syndrome and fertility —Impact of X‐chromosomal inheritance on spermatogenesis
Andrologia,Volume 50, Issue 5, June 2018. (Source: Andrologia)
Source: Andrologia - March 7, 2018 Category: Urology & Nephrology Authors: S.
Franik
,
D.
Smeets
,
G.
van de
Zande
,
I.
Gomes
,
K.
D'Hauwers
,
D. D. M.
Braat
,
K.
Fleischer
,
L.
Ramos Source Type: research
Improvement in sperm functional competence through modified low ‐dose packaging in French mini straws of bull semen
Andrologia,Volume 50, Issue 5, June 2018. (Source: Andrologia)
Source: Andrologia - March 7, 2018 Category: Urology & Nephrology Authors: P.
Karan
,
T. K.
Mohanty
,
A.
Kumaresan
,
M.
Bhakat
,
R. K.
Baithalu
,
K.
Verma
,
S.
Kumar
,
M.
Das Gupta
,
K. K.
Saraf
,
S. C.
Gahlot Source Type: research
Quercetin and rutin ameliorates sulphasalazine ‐induced spermiotoxicity, alterations in reproductive hormones and steroidogenic enzyme imbalance in rats
Andrologia, EarlyView. (Source: Andrologia)
Source: Andrologia - March 7, 2018 Category: Urology & Nephrology Source Type: research
