An unusual polynodular liver disease: Multiple biliary hamartoma
This report describes an unusual case of multiple biliary hamartomas and reviews the literature regarding the incidence, pathogenesis, and diagnosis of this disease. (Source: Advances in Digestive Medicine)
Source: Advances in Digestive Medicine - December 16, 2014 Category: Gastroenterology Source Type: research

Impact of interleukin-28B polymorphism on HCV-1 infected patients treated with response-guided therapy
Conclusion For HCV-1 infected patients who were treated with RGT, the IL28B unfavorable genotype predicted a higher relapse rate; RVR and IL28B favorable genotype were independent factors associated with SVR in patients treated with RGT. (Source: Advances in Digestive Medicine)
Source: Advances in Digestive Medicine - December 13, 2014 Category: Gastroenterology Source Type: research

Risk factors of incomplete response to proton pump inhibitor therapy in patients with mild erosive esophagitis
Conclusion Of the patients with Los Angeles Grade A/B erosive esophagitis, 21.6% failed to have complete symptom resolution following 8-week PPI therapy. Globus and insomnia are two independent factors predicting incomplete symptom response in patients with mild erosive esophagitis. (Source: Advances in Digestive Medicine)
Source: Advances in Digestive Medicine - December 13, 2014 Category: Gastroenterology Source Type: research

Primary duodenal Burkitt lymphoma presenting as sessile, button-like bleeding polyps
We report the case of a 70-year-old woman admitted to our ward with upper GI bleeding due to duodenal polyps. An upper GI endoscopic examination showed button-like polyps with central depression, and an immunohistochemical study of the polyps revealed a high-grade B cell malignancy (BL). Consequently, the patient was treated with aggressive chemotherapy. The tumors regressed after chemotherapy. Although primary duodenal Burkitt lymphoma is very rare, the possibility of malignancy should be considered if a patient presents with duodenal button-like polyps with a central depressed surface. (Source: Advances in Digestive Medicine)
Source: Advances in Digestive Medicine - December 10, 2014 Category: Gastroenterology Source Type: research

Different schedules of bowel preparation with sodium phosphate lead to different bowel cleansing effects and adenoma detection rates at colonoscopy
Conclusion Modifying the time schedule of bowel preparation could improve bowel cleansing quality and increase the colonic ADR in a health management center. (Source: Advances in Digestive Medicine)
Source: Advances in Digestive Medicine - December 1, 2014 Category: Gastroenterology Source Type: research

Reviewer Acknowledgments
Publication date: December 2014 Source:Advances in Digestive Medicine, Volume 1, Issue 4 (Source: Advances in Digestive Medicine)
Source: Advances in Digestive Medicine - November 27, 2014 Category: Gastroenterology Source Type: research

Single-balloon enteroscopy-assisted nasojejunal tube placement
Publication date: March 2014 Source:Advances in Digestive Medicine, Volume 1, Issue 1 Author(s): Hsuan-Wei Chen , Peng-Jen Chen , Wei-Kuo Chang , Tsai-Yuan Hsieh , Tien-Yu Huang Expertise in enteral nutrition is an important aspect of the skill set of clinical gastroenterologists. Feeding tubes can be placed by bedside, endoscopic, fluoroscopic, and surgical methods. Nasojejunal tube placement in patients with variations in anatomy or with a history of abdominal surgery was previously a difficult problem. Today, however, as a result of developments in enteroscopy, gastroenterologists can obtain a better understand...
Source: Advances in Digestive Medicine - October 23, 2014 Category: Gastroenterology Source Type: research

Advanced hepatocellular carcinoma treated by a combination of sorafenib and radiotherapy
We report here the case of a patient with advanced hepatocellular carcinoma who had an impressive response to a combination of sorafenib and radiotherapy. The treatment was well tolerated with no unexpected toxicities. Post-treatment imaging showed a satisfactory partial response with regression of the tumor by more than 50%. (Source: Advances in Digestive Medicine)
Source: Advances in Digestive Medicine - October 23, 2014 Category: Gastroenterology Source Type: research

Modified endoscopic mucosal resection of gastric heterotopic pancreas: Report of two cases
Publication date: March 2014 Source:Advances in Digestive Medicine, Volume 1, Issue 1 Author(s): Po-Hao Liao , Horng-Yuan Wang , Shou-Chuan Shih , Ming-Jen Chen Heterotopic pancreas is a congenital anomaly characterized by the presence of ectopic pancreatic tissue far from the pancreas. The treatment of heterotopic pancreas may include expectant observation, endoscopic resection, or surgery. The aim of this study was to describe the technique of cap-assisted endoscopic mucosal resection for the management of heterotopic pancreas of the stomach. Two patients, a 41-year-old woman and a 31-year-old man, were referred ...
Source: Advances in Digestive Medicine - October 23, 2014 Category: Gastroenterology Source Type: research

High pre-operative serum aminotransferase levels predict local recurrence after curative resection of hepatocellular carcinoma
Conclusion Although this is a small-scale study, our findings could be easily applied clinically and used as readily available indicators to help the follow-up algorithm. We also suggest antiviral management as soon as possible for patients with hepatocellular carcinoma undergoing curative resection, especially those with a high preoperative aspartate aminotransferase level. (Source: Advances in Digestive Medicine)
Source: Advances in Digestive Medicine - October 23, 2014 Category: Gastroenterology Source Type: research

Analgesic effect of premedication with meperidine in patients undergoing colonoscopy without sedation
Conclusion In our study, premedication with meperidine or no premedication was not associated with a reduction in abdominal pain during colonoscopy without sedation. The insertion time and cecal intubation rate showed no difference between patients with or without additional analgesic drugs prior to the procedure. However, as self-selection bias could not be ruled out, further randomized, placebo-controlled trials are needed to confirm our findings. (Source: Advances in Digestive Medicine)
Source: Advances in Digestive Medicine - October 23, 2014 Category: Gastroenterology Source Type: research

Outcome for self-expandable metal stents in patients with malignant gastroduodenal obstruction: A single center experience
Conclusion Metallic stent placement is an effective and relatively safe treatment for patients with malignant gastric outlet obstruction. (Source: Advances in Digestive Medicine)
Source: Advances in Digestive Medicine - October 23, 2014 Category: Gastroenterology Source Type: research

Thalidomide induces complete remission of advanced hepatocellular carcinoma
We report a 65-year-old male patient with alcoholic liver cirrhosis that was diagnosed having multiple HCCs during surveillance. The patient was assessed as inoperable and unsuited for transhepatic arterial chemoembolization or systemic chemotherapy. After discussing the therapeutic alternatives, he decided to receive low-dose thalidomide (100 mg daily) therapy. Fortunately, follow-up liver biochemical tests, serum α-fetoprotein level, and dynamic computed tomography showed complete remission of the HCCs 4.5 months after thalidomide treatment and this was documented for more than 22 months without evidence of tumor recur...
Source: Advances in Digestive Medicine - October 23, 2014 Category: Gastroenterology Source Type: research

Immunoglobulin G4-related disease presenting with obstructive jaundice
Publication date: June 2014 Source:Advances in Digestive Medicine, Volume 1, Issue 2 Author(s): Yuan-Rung Li , Chan-Feng Pan , Hoi-Hung Chan , Kowk-Hung Lai , Ping-I Hsu A 48-year-old male presented with diffuse abdominal fullness for 1 month and tea-colored urine for 10 days. Abdominal computed tomography/magnetic resonance cholangiopancreatography revealed diffuse enlargement of the pancreas and unusual soft tissue density around the left ureter. Endoscopic retrograde cholangiopancreatography demonstrated lumen narrowing of the distal common bile duct and irregularity of the pancreatic duct. Markedly elevated se...
Source: Advances in Digestive Medicine - October 23, 2014 Category: Gastroenterology Source Type: research

Empiric antibiotic choices for community-acquired biliary tract infections
Conclusion The combination of ceftriaxone plus metronidazole appears to be the most appropriate empiric antibiotics for the treatment of CA-BTI at this hospital. Because different hospitals may encounter microorganisms of different antimicrobial susceptibilities, similar approaches may be followed by other hospitals where appropriate empiric therapy has not yet been established for the treatment of CA-BTI. (Source: Advances in Digestive Medicine)
Source: Advances in Digestive Medicine - October 23, 2014 Category: Gastroenterology Source Type: research