A real-time and modular approach for quick detection and mechanism exploration of DPIs with different carrier particle sizes
Publication date: Available online 21 June 2021Source: Acta Pharmaceutica Sinica BAuthor(s): Yingtong Cui, Ying Huang, Xuejuan Zhang, Xiangyun Lu, Jun Xue, Guanlin Wang, Ping Hu, Xiao Yue, Ziyu Zhao, Xin Pan, Chuanbin Wu (Source: Acta Pharmaceutica Sinica B)
Source: Acta Pharmaceutica Sinica B - June 22, 2021 Category: Cancer & Oncology Source Type: research
The osteogenic niche-targeted arsenic nanoparticles prevent colonization of disseminated breast tumor cells in the bone
Publication date: Available online 21 June 2021Source: Acta Pharmaceutica Sinica BAuthor(s): Cong Liu, Anzhi Hu, Huijuan Chen, Jing Liang, Mancang Gu, Yang Xiong, Chao-Feng Mu (Source: Acta Pharmaceutica Sinica B)
Source: Acta Pharmaceutica Sinica B - June 22, 2021 Category: Cancer & Oncology Source Type: research
Design of ultrahigh-affinity and dual-specificity peptide antagonists of MDM2 and MDMX for P53 activation and tumor suppression
Publication date: Available online 18 June 2021Source: Acta Pharmaceutica Sinica BAuthor(s): Xiang Li, Neelakshi Gohain, Si Chen, Yinghua Li, Xiaoyuan Zhao, Bo Li, William D. Tolbert, Wangxiao He, Marzena Pazgier, Honggang Hu, Wuyuan Lu (Source: Acta Pharmaceutica Sinica B)
Source: Acta Pharmaceutica Sinica B - June 19, 2021 Category: Cancer & Oncology Source Type: research
A review of existing strategies for designing long-acting parenteral formulations: Focus on underlying mechanisms, and future perspectives
Publication date: Available online 17 June 2021Source: Acta Pharmaceutica Sinica BAuthor(s): Yujie Shi, An Lu, Xiangyu Wang, Zakia Belhadj, Jiancheng Wang, Qiang Zhang (Source: Acta Pharmaceutica Sinica B)
Source: Acta Pharmaceutica Sinica B - June 18, 2021 Category: Cancer & Oncology Source Type: research
A cyclodextrin-based nanoformulation achieves co-delivery of ginsenoside Rg3 and quercetin for chemo-immunotherapy in colorectal cancer
Publication date: Available online 18 June 2021Source: Acta Pharmaceutica Sinica BAuthor(s): Dandan Sun, Yifang Zou, Liu Song, Shulan Han, Hao Yang, Di Chu, Yun Dai, Jie Ma, Caitriona M. O’Driscoll, Zhuo Yu, Jianfeng Guo (Source: Acta Pharmaceutica Sinica B)
Source: Acta Pharmaceutica Sinica B - June 18, 2021 Category: Cancer & Oncology Source Type: research
Synergistic effects of autophagy/mitophagy inhibitors and magnolol promote apoptosis and antitumor efficacy
Publication date: Available online 16 June 2021Source: Acta Pharmaceutica Sinica BAuthor(s): Yancheng Tang, Liming Wang, Tao Yi, Jun Xu, Jigang Wang, Jiang-Jiang Qin, Qilei Chen, Ka-Man Yip, Yi-Hang Pan, Peng Hong, Ying-Ying Lu, Han-Ming Shen, Hu-Biao Chen (Source: Acta Pharmaceutica Sinica B)
Source: Acta Pharmaceutica Sinica B - June 18, 2021 Category: Cancer & Oncology Source Type: research
MiR-7/TGF-beta2 axis sustains acidic tumor microenvironment-induced lung cancer metastasis
Publication date: Available online 17 June 2021Source: Acta Pharmaceutica Sinica BAuthor(s): Tao Su, Suchao Huang, Yanmin Zhang, Yajuan Guo, Shuwei Zhang, Jiaji Guan, Mingjing Meng, Linxin Liu, Caiyan Wang, Dihua Yu, Hiu-Yee Kwan, Zhiying Huang, Qiuju Huang, Elaine Lai-Han Leung, Ming Hu, Ying Wang, Zhongqiu Liu, Linlin Lu (Source: Acta Pharmaceutica Sinica B)
Source: Acta Pharmaceutica Sinica B - June 18, 2021 Category: Cancer & Oncology Source Type: research
Light-controllable charge-reversal nanoparticles with polyinosinic-polycytidylic acid for enhancing immunotherapy of triple negative breast cancer
Publication date: Available online 15 June 2021Source: Acta Pharmaceutica Sinica BAuthor(s): Lei Fang, Zitong Zhao, Jue Wang, Ping Xiao, Xiangshi Sun, Yaping Ding, Pengcheng Zhang, Dangge Wang, Yaping Li (Source: Acta Pharmaceutica Sinica B)
Source: Acta Pharmaceutica Sinica B - June 16, 2021 Category: Cancer & Oncology Source Type: research
A small molecule UPR modulator for diabetes identified by high throughput screening
Publication date: Available online 16 June 2021Source: Acta Pharmaceutica Sinica BAuthor(s): Valeria Marrocco, Tuan Tran, Siying Zhu, Seung Hyuk Choi, Ana M. Gamo, Sijia Li, Qiangwei Fu, Marta Diez Cunado, Jason Roland, Mitch Hull, Van Nguyen-Tran, Sean Joseph, Arnab K. Chatterjee, Nikki Rogers, Matthew S. Tremblay, Weijun Shen (Source: Acta Pharmaceutica Sinica B)
Source: Acta Pharmaceutica Sinica B - June 16, 2021 Category: Cancer & Oncology Source Type: research
Fucoidan-functionalized activated platelet-hitchhiking micelles simultaneously track tumor cells and remodel the immunosuppressive microenvironment for efficient metastatic cancer treatment
Publication date: Available online 16 June 2021Source: Acta Pharmaceutica Sinica BAuthor(s): Rong Guo, Miao Deng, Xuan He, Mengmeng Li, Jiaxin Li, Penghui He, Houqin Liu, Man Li, Zhirong Zhang, Qin He (Source: Acta Pharmaceutica Sinica B)
Source: Acta Pharmaceutica Sinica B - June 16, 2021 Category: Cancer & Oncology Source Type: research
Identification of a novel PHGDH covalent inhibitor by chemical proteomics and phenotypic profiling
Publication date: Available online 16 June 2021Source: Acta Pharmaceutica Sinica BAuthor(s): Chen Chen, Tianyu Zhu, Xiaoqin Liu, Dongrong Zhu, Yi Zhang, Sifang Wu, Chao Han, Hao Zhang, Jianguang Luo, Lingyi Kong (Source: Acta Pharmaceutica Sinica B)
Source: Acta Pharmaceutica Sinica B - June 16, 2021 Category: Cancer & Oncology Source Type: research
A NIR fluorescent probe for Vanin-1 and its applications in imaging, kidney injury diagnosis, and the development of inhibitor
Publication date: Available online 8 June 2021Source: Acta Pharmaceutica Sinica BAuthor(s): Zhenhao Tian, Fei Yan, Xiangge Tian, Lei Feng, Jingnan Cui, Sa Deng, Baojing Zhang, Tian Xie, Shanshan Huang, Xiaochi Ma (Source: Acta Pharmaceutica Sinica B)
Source: Acta Pharmaceutica Sinica B - June 9, 2021 Category: Cancer & Oncology Source Type: research
Hepatotoxicity reports in the FDA adverse event reporting system database: A comparison of drugs that cause injury via mitochondrial or other mechanisms
Publication date: Available online 7 June 2021Source: Acta Pharmaceutica Sinica BAuthor(s): Payal Rana, Michael D. Aleo, Xuerong Wen, Stephen Kogut (Source: Acta Pharmaceutica Sinica B)
Source: Acta Pharmaceutica Sinica B - June 8, 2021 Category: Cancer & Oncology Source Type: research
Genetically-engineered “all-in-one” vaccine platform for cancer immunotherapy
Publication date: Available online 8 June 2021Source: Acta Pharmaceutica Sinica BAuthor(s): Aihua Wu, Yingzhi Chen, Hairui Wang, Ya Chang, Meng Zhang, Pengfei Zhao, Yisi Tang, Qin Xu, Zhuangzhi Zhu, Yang Cao, Yongzhuo Huang (Source: Acta Pharmaceutica Sinica B)
Source: Acta Pharmaceutica Sinica B - June 8, 2021 Category: Cancer & Oncology Source Type: research
Combination therapy with miR34a and doxorubicin synergistically inhibits Dox-resistant breast cancer progression via down-regulation of SNAIL through suppressing NOTCH/NF-κB and RAS/RAF/MEK/ERK signaling pathway
Publication date: Available online 8 June 2021Source: Acta Pharmaceutica Sinica BAuthor(s): Xiaoxia Yang, Pengfei Shang, Bingfang Yu, Qiuyang Jin, Jing Liao, Lei Wang, Jianbo Ji, Xiuli Guo (Source: Acta Pharmaceutica Sinica B)
Source: Acta Pharmaceutica Sinica B - June 8, 2021 Category: Cancer & Oncology Source Type: research
