Acta Neurologica Scandinavica. Supplementum 
This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.
This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.Reduced immunoglobulin levels in epilepsy patients treated with levetiracetam, lamotrigine, or carbamazepine.
CONCLUSIONS: Low levels of immunoglobulins were found in patients with epilepsy treated with LTG or CBZ. As our group of patients consisted of otherwise healthy young adults, one should be especially aware of a possible effect of AEDs on immunoglobulin levels when treating selected patient groups, for example immunocompromised patients. Immunoglobulin concentrations should be measured in patients treated with LTG or CBZ who experience recurrent infections, and a change in medication should be considered.
PMID: 23190286 [PubMed - in process] (Source: Acta Neurologica Scandinavica. Supplementum)
Source: Acta Neurologica Scandinavica. Supplementum - January 11, 2013 Category: Neurology Authors: Svalheim S, Mushtaq U, Mochol M, Luef G, Rauchenzauner M, Frøland SS, Taubøll E Tags: Acta Neurol Scand Suppl Source Type: research
Fat-soluble vitamins as disease modulators in multiple sclerosis.
CONCLUSION: Vitamin D is a promising candidate as modulator of disease activity in MS, and controlled studies are currently being conducted. All the fat-soluble vitamins have, however, been demonstrated to be effective in different animal models for the disease, and vitamin A and E have biological properties that could be relevant for MS pathogenesis. Thus, vitamin A and E seem to be promising candidates for future case-control and cohort studies.
PMID: 23190287 [PubMed - in process] (Source: Acta Neurologica Scandinavica. Supplementum)
Source: Acta Neurologica Scandinavica. Supplementum - January 11, 2013 Category: Neurology Authors: Torkildsen O, Løken-Amsrud KI, Wergeland S, Myhr KM, Holmøy T Tags: Acta Neurol Scand Suppl Source Type: research
Clinical assessment and management of sleep disorders in multiple sclerosis: a literature review.
Abstract
The major sleep disorders are common in multiple sclerosis (MS) and are associated with significant morbidity. Despite this, the rate of recognition and management of these conditions are low. All types of sleep disorders are seen in patients with MS: insomnia, circadian rhythm sleep disorders, sleep-related movement disorders, sleep-related breathing disorders, hypersomnia (narcolepsy), and parasomnia (REM sleep behavior disorder; RBD). This literature review covers the prevalence, clinical features, and treatment of sleep disorders in MS. Based on clinical experience, the spectrum of symptoms as...
Source: Acta Neurologica Scandinavica. Supplementum - January 11, 2013 Category: Neurology Authors: Lunde HM, Bjorvatn B, Myhr KM, Bø L Tags: Acta Neurol Scand Suppl Source Type: research
Pseudoprogression in high-grade glioma.
Abstract
Pseudoprogression is a treatment-related effect seen on imaging in high-grade glioma. Enhancement of gadolinium contrast on control MRI can be misinterpreted as tumor recurrence and is also difficult to distinguish from radiation necrosis. Pseudoprogression is seen in up to 30% after standard treatment for glioblastoma multiforme (GBM), which is radiotherapy concurrent with chemotherapy with temozolomide (TMZ) and adjuvant cycles of TMZ. In this article, the current literature on pseudoprogression in high-grade glioma is reviewed by searches in PubMed. We also present two clinical cases, one of wh...
Source: Acta Neurologica Scandinavica. Supplementum - January 11, 2013 Category: Neurology Authors: Knudsen-Baas KM, Moen G, Fluge O, Storstein A Tags: Acta Neurol Scand Suppl Source Type: research
Chronic Lyme; diagnostic and therapeutic challenges.
Abstract
In this review, we aim to discuss the definition, clinical and laboratory features, diagnostics, and management of chronic Lyme. Chronic Lyme is a rare condition caused by long-lasting and ongoing infection with the spirochete Borrelia burgdorferi (Bb). The most common manifestations are progressive encephalitis, myelitis, acrodermatitis chronica atrophicans with or without neuropathy, and arthritis. Chronic Lyme is not considered to present with isolated subjective symptoms. Direct detection of Bb has low yield in most manifestations of chronic Lyme, while almost 100% of the cases are seropositiv...
Source: Acta Neurologica Scandinavica. Supplementum - January 11, 2013 Category: Neurology Authors: Ljøstad U, Mygland A Tags: Acta Neurol Scand Suppl Source Type: research
Chronic inflammatory demyelinating polyneuropathy (CIDP).
CONCLUSIONS: It is important to recognize these immune-mediated neuropathies as they respond to treatment.
PMID: 23190291 [PubMed - in process] (Source: Acta Neurologica Scandinavica. Supplementum)
Source: Acta Neurologica Scandinavica. Supplementum - January 11, 2013 Category: Neurology Authors: Vedeler CA, Farbu E, Mellgren SI Tags: Acta Neurol Scand Suppl Source Type: research
Visual impairment in stroke patients - a review.
Abstract
Approximately 30% of all stroke patients suffer from post-stroke visual impairment. Hemianopia is the most common symptom, but also neglect, diplopia, reduced visual acuity, ptosis, anisocoria, and nystagmus are frequent. Partial or complete recovery of visual disorders can occur, but many patients suffer permanent disability. This disability is often less evident than impairment of motor and speech functions, but is negatively correlated with rehabilitation outcome and can lead to a significant reduction in day-to-day functioning. To be visually impaired after stroke reduces quality of life and c...
Source: Acta Neurologica Scandinavica. Supplementum - January 11, 2013 Category: Neurology Authors: Sand KM, Midelfart A, Thomassen L, Melms A, Wilhelm H, Hoff JM Tags: Acta Neurol Scand Suppl Source Type: research
Acute ischemic stroke - from symptom recognition to thrombolysis.
CONCLUSIONS: As neuronal death in stroke patients occurs in a time-dependent fashion, all effort should be made to decrease time from symptom onset to treatment start with rtPA: major challenges are stroke recognition in the public, transport times to hospital and an efficient stroke triage in the hospital.
PMID: 23190293 [PubMed - in process] (Source: Acta Neurologica Scandinavica. Supplementum)
Source: Acta Neurologica Scandinavica. Supplementum - January 11, 2013 Category: Neurology Authors: Kurz MW, Kurz KD, Farbu E Tags: Acta Neurol Scand Suppl Source Type: research
Patient selection for intra-arterial cerebral revascularization in acute ischemic stroke.
Abstract
In acute ischemic stroke, rapid revascularization of the cerebral 'penumbra volume' is the key to better patient outcome. The largest and most proximal cerebral thrombotic artery occlusions can in most cases only be opened by intra-arterial intervention. The use of intra-arterial revascularization is rapidly expanding throughout Europe and North America, despite the risk for serious complications and the fact that the benefit of this treatment has not yet been proven in large, randomized clinical trials. Oslo University Hospital has performed approximately 60 intra-arterial procedures annually in ...
Source: Acta Neurologica Scandinavica. Supplementum - January 11, 2013 Category: Neurology Authors: Lund CG, Aamodt AH, Russell D Tags: Acta Neurol Scand Suppl Source Type: research
Very long-term mortality after ischemic stroke: : predictors of cardiovascular death.
This study shows that age, male gender, stroke severity, hemorrhagic stroke, diabetes, ischemic heart disease, and right hemispheric stroke are predictors associated with increased risk of long-term cardiovascular mortality. Neither atrial fibrillation, antihypertensive treatment on admission, smoking, or living alone was risk factors for late cardiovascular deaths.
PMID: 23190295 [PubMed - in process] (Source: Acta Neurologica Scandinavica. Supplementum)
Source: Acta Neurologica Scandinavica. Supplementum - January 11, 2013 Category: Neurology Authors: Rønning OM Tags: Acta Neurol Scand Suppl Source Type: research
A vascular approach to mild amnestic cognitive impairment: a pilot study.
CONCLUSIONS: Pure amnestic MCI is probably less associated with cerebrovascular disease and may be more consistent with evolving Alzheimer's disease. However, vascular risk factors are common in these patients.
PMID: 23190296 [PubMed - in process] (Source: Acta Neurologica Scandinavica. Supplementum)
Source: Acta Neurologica Scandinavica. Supplementum - January 11, 2013 Category: Neurology Authors: Fromm A, Lundervold AJ, Moen G, Skulstad S, Thomassen L Tags: Acta Neurol Scand Suppl Source Type: research
