Midostaurin cut organ damage in systemic mastocytosis
Midostaurin completely resolved at least one type of organ damage for 45% of patients with advanced systemic mastocytosis, based on a multicenter, open-label, phase II, industry-sponsored trial.
“Response rates were similar regardless of the subtype of advanced systemic mastocytosis, KIT mutation... (Source: Skin and Allergy News)
Source: Skin and Allergy News - June 29, 2016 Category: Dermatology Source Type: news
Poor outcome for PBC patient with bullous pemphigoid
A 45-year-old woman who was admitted with concurrent primary biliary cirrhosis or cholangitis (PBC) and bullous pemphigoid died 5 days after admittance, according to a case report from N.B. Guerra-Uribe, MD, and M.S. González-Huezo, MD.
The patient was admitted to the emergency department for... (Source: Skin and Allergy News)
Source: Skin and Allergy News - June 29, 2016 Category: Dermatology Source Type: news
VIDEO: TNF inhibitors improved refractory skin disease in juvenile dermatomyositis
LONDON – Tumor necrosis factor–inhibitor treatment improved refractory skin disease in juvenile dermatomyositis patients in the largest observational study of its kind from the United Kingdom and Ireland Juvenile Dermatomyositis Research Group.
Muscle disease in the juvenile dermatomyositis (JDM)... (Source: Skin and Allergy News)
Source: Skin and Allergy News - June 27, 2016 Category: Dermatology Source Type: news
Actemra may reduce scleroderma skin thickening
The interleukin-6 inhibitor tocilizumab (Actemra) substantially reduced skin thickening in patients with systemic sclerosis in the “proof-of concept” faSScinate trial, the results of which have now been published in the Lancet.
The mean change in the primary endpoint of a modified Rodnan skin... (Source: Skin and Allergy News)
Source: Skin and Allergy News - June 27, 2016 Category: Dermatology Source Type: news
Checkpoint-blocking antibodies appear safe, beneficial in elderly melanoma patients
CHICAGO – Programmed cell death protein 1 (PD-1) inhibitors and combination ipilimumab and nivolumab prolonged survival, compared with ipilimumab alone in patients aged 80 and older with advanced melanoma, and the patients experienced no more adverse events than did patients of all age groups in... (Source: Skin and Allergy News)
Source: Skin and Allergy News - June 26, 2016 Category: Dermatology Source Type: news
Obesity may attenuate anti-TNF response in psoriatic arthritis
LONDON – Patients with psoriatic arthritis appear less likely to achieve a good response to their first anti–tumor necrosis factor (anti-TNF) therapy if they are obese, according to data taken from two Nordic registries.
In a large observational cohort study, obese individuals with psoriatic... (Source: Skin and Allergy News)
Source: Skin and Allergy News - June 25, 2016 Category: Dermatology Source Type: news
There’s still a place for HA fillers in fine facial lines
NEWPORT BEACH, CALIF. – Despite all the technical advances in aesthetic medicine, there’s still a place for treating fine facial lines with thin hyaluronic acid fillers, according to Dr. Mark G. Rubin, a dermatologist at the Lasky Skin Center in Beverly Hills, Calif.
“In the last couple of years,... (Source: Skin and Allergy News)
Source: Skin and Allergy News - June 25, 2016 Category: Dermatology Source Type: news
SEER data underscore mortality associated with thin melanomas
SCOTTSDALE, ARIZ. – Thin melanomas account for most melanoma deaths, even though T4 lesions have the worst prognosis, according to an analysis of melanoma data from the National Cancer Institute’s Surveillance, Epidemiology, and End Results (SEER) program.
In 2015, a study from Queensland,... (Source: Skin and Allergy News)
Source: Skin and Allergy News - June 23, 2016 Category: Dermatology Source Type: news
Supreme Court deadlocks on immigration policy case
Supreme Court justices have deadlocked on whether protections for undocumented immigrants can be expanded under an executive order by the President.
In a June 23 decision, justices were equally divided on the constitutionality of two of President Obama’s immigration policies: the Deferred Action... (Source: Skin and Allergy News)
Source: Skin and Allergy News - June 23, 2016 Category: Dermatology Source Type: news
House Republicans unveil long-awaited plan to replace health law
Six years after promising a plan to “repeal and replace” the federal health law, House Republicans are finally ready to deliver.
The 37-page white paper, called “A Better Way,” includes virtually every... (Source: Skin and Allergy News)
Source: Skin and Allergy News - June 22, 2016 Category: Dermatology Source Type: news
Medicare Trust Fund projected to run dry in 2028
The Medicare Trust Fund is projected to become insolvent in 2028, 2 years earlier than projected this time last year.
The change is based on two key factors: an expected reduction in payroll taxes and a slowdown in declining rate of inpatient utilization, Andy Slavitt, acting administrator of the... (Source: Skin and Allergy News)
Source: Skin and Allergy News - June 22, 2016 Category: Dermatology Source Type: news
Dos and don’ts of dealing with disruptive behavior
CHICAGO – Dealing with disruptive behavior by staff and colleagues isn’t just about knowing what to do – it’s also about knowing what not to do.
Often, mishandling disruptive behavior can make matters worse and lead to further conflict among physicians and employees, health law experts warn. At a... (Source: Skin and Allergy News)
Source: Skin and Allergy News - June 22, 2016 Category: Dermatology Source Type: news
Updated Behçet’s disease recommendations expand biologic treatment
LONDON – A EULAR task force issued the first update to recommendations for managing Behçet’s disease since 2008, with revised recommendations that reflect expanded use of biologic agents, and increased evidence to guide management of gastrointestinal involvement, use of anticoagulants in patients... (Source: Skin and Allergy News)
Source: Skin and Allergy News - June 20, 2016 Category: Dermatology Source Type: news
Skin patch testing pinpoints dietary triggers of IBS
SAN DIEGO – About 90% of patients reported improvement in symptoms of irritable bowel syndrome after avoiding type 4 food allergens identified by skin patch testing, according to an uncontrolled study.
Furthermore, 69% of patients reported at least moderate improvement after eliminating foods to... (Source: Skin and Allergy News)
Source: Skin and Allergy News - June 18, 2016 Category: Dermatology Source Type: news
Donor blood testing highlights increasing Zika risk in Puerto Rico
An increasing prevalence of Zika virus infection detected among blood donors in Puerto Rico using a highly sensitive, investigational nucleic acid test likely reflects an overall increase in the incidence of infection in the population at large, according to the Centers for Disease Control and... (Source: Skin and Allergy News)
Source: Skin and Allergy News - June 17, 2016 Category: Dermatology Source Type: news
