Docs to CMS: MACRA is too complex and should be delayed
The proposed federal regulations to implement the MACRA health care reforms are too complex, too onerous on small and solo practices, lack opportunities for many to participate in alternative payment models, and should be delayed for a full year, at least.
That was the message that emerged from... (Source: Skin and Allergy News)
Source: Skin and Allergy News - July 9, 2016 Category: Dermatology Source Type: news
Mechanism proposed for microvascular thrombosis in thrombotic thrombocytopenic purpura
In patients with acquired autoimmune thrombotic thrombocytopenic purpura, elevated plasma levels of human neutrophil proteins 1-3 inhibit proteolytic cleavage of von Willebrand factor by ADAMTS13, Vikram G. Pillai, PhD, of the University of Alabama at Birmingham, and colleagues reported.
The... (Source: Skin and Allergy News)
Source: Skin and Allergy News - July 8, 2016 Category: Dermatology Source Type: news
Study tracks distant metastatic patterns of Merkel cell carcinoma
SCOTTSDALE, ARIZ. – Distant metastatic sites of Merkel cell carcinoma most often involved the supraclavicular, retroperitoneal, and iliac lymph nodes, in a single center retrospective study of 305 patients.
Merkel cell carcinoma metastases “clearly favored distant nodes, but the distribution of... (Source: Skin and Allergy News)
Source: Skin and Allergy News - July 7, 2016 Category: Dermatology Source Type: news
Nonwhite race, lower socioeconomic status predicts persistently active AD
SCOTTSDALE, ARIZ. – Among patients with atopic dermatitis, persistently active disease was significantly more common among females of nonwhite race with a history of atopy than among patients without these characteristics, in an analysis of survey data from the Pediatric Elective Eczema... (Source: Skin and Allergy News)
Source: Skin and Allergy News - July 7, 2016 Category: Dermatology Source Type: news
Dual immune checkpoint blockade found durable in melanoma
CHICAGO – Immune checkpoint blockade, especially with a combination of agents having complementary mechanisms of action, has durable efficacy when used as initial therapy for advanced melanoma, according to an update of the CheckMate 067 trial.
The trial randomized 945 treatment-naive patients... (Source: Skin and Allergy News)
Source: Skin and Allergy News - July 7, 2016 Category: Dermatology Source Type: news
Severe psoriasis upped lymphoma risk in large cohort study
SCOTTSDALE, ARIZ. – Psoriasis of all severities was linked to a 3.5-fold increase in risk of cutaneous T-cell lymphoma, and severe psoriasis upped the associated risk of Hodgkin lymphoma by about 2.5 times, in a large, longitudinal, population-based cohort study.
Psoriasis also was tied to a... (Source: Skin and Allergy News)
Source: Skin and Allergy News - July 6, 2016 Category: Dermatology Source Type: news
Decision Support in Medicine: Herpes Zoster
1. Are you confident of the diagnosis?What you should be alert for in the historyA history of prodrome with acute stinging, itching, burning, paresthesias, and hyperesthesia in a single dermatome is characteristic of herpes zoster. Patients may also complain of... (Source: Skin and Allergy News)
Source: Skin and Allergy News - July 5, 2016 Category: Dermatology Source Type: news
Case series describes melanoma-associated leukoderma presenting as atypical vitiligo
Consider melanoma-associated leukoderma (MAL) as a possible diagnosis in patients presenting with atypical vitiligo-like skin depigmentation that is refractory to standard treatment, advised the authors of a series of seven such cases.
In a research letter published online in the British Journal... (Source: Skin and Allergy News)
Source: Skin and Allergy News - July 5, 2016 Category: Dermatology Source Type: news
Supreme Court will not hear pharmacy religious liberty case
The U.S. Supreme Court has refused to decide whether pharmacists with strongly held religious beliefs can be forced to dispense emergency contraception to patients.
Justices did not explain their June 28 denial of <a... (Source: Skin and Allergy News)
Source: Skin and Allergy News - July 1, 2016 Category: Dermatology Source Type: news
Multisite NIH-sponsored research can now use single IRB
In an effort to streamline multisite clinical research, the National Institutes of Health announced a new policy related to the use of institutional review boards (IRBs).
(Source: Skin and Allergy News)
Source: Skin and Allergy News - July 1, 2016 Category: Dermatology Source Type: news
Analysis supports daily folate for children with psoriasis on methotrexate
SCOTTSDALE, ARIZ. – Children and adolescents receiving methotrexate for psoriasis were significantly less likely to experience gastrointestinal side effects when they took a folate supplement every day instead of once weekly or 6 days a week, in a retrospective study of more than 400 pediatric... (Source: Skin and Allergy News)
Source: Skin and Allergy News - July 1, 2016 Category: Dermatology Source Type: news
Significant race and health care disparities exist among hospitalized psoriasis patients
Significant racial and health care disparities exist among hospitalized psoriasis patients, according to a recent study by Derek Y. Hsu of the Department of Dermatology at Northwestern University, Chicago, and his coauthors.
Researchers looked at a sample representative of 20% of all U.S.... (Source: Skin and Allergy News)
Source: Skin and Allergy News - June 30, 2016 Category: Dermatology Source Type: news
T-VEC plus ipilimumab safe, effective in advanced melanoma
Talimogene laherparepvec (T-VEC) combined with ipilimumab was more effective in treating advanced melanoma than either treatment alone, report Igor Puzanov, MD, of Vanderbilt University Medical Center in Nashville, Tenn., and coauthors.
In a phase Ib trial of 19 patients with advanced melanoma,... (Source: Skin and Allergy News)
Source: Skin and Allergy News - June 30, 2016 Category: Dermatology Source Type: news
Ustekinumab misses primary endpoint in atopic dermatitis
SCOTTSDALE, ARIZ. – Treatment with ustekinumab did not result in significant improvements in atopic dermatitis after 16 weeks, compared with placebo in a phase II study of adults with moderate to severe atopic dermatitis, Dr. Patrick Brunner reported at the annual meeting of the Society for... (Source: Skin and Allergy News)
Source: Skin and Allergy News - June 30, 2016 Category: Dermatology Source Type: news
Rash, microcephaly not always present with congenital Zika syndrome
The largest study so far of congenital Zika virus syndrome suggests that microcephaly and maternal rash are not sufficient to detect affected babies.
Writing in the June 29 online edition of The Lancet, researchers report on a case series of 1,501 liveborn infants with suspected congenital Zika... (Source: Skin and Allergy News)
Source: Skin and Allergy News - June 29, 2016 Category: Dermatology Source Type: news
